University of California San Francisco
Helen Diller Family Comprehensive Cancer Center

Inaugural Chemical Biology Consortium Symposium: Bridging the Gaps of Drug Discovery

November 16, 2018, 8:00 am – 6:30 pm

Mission Bay Conference Center
1675 Owens Street, Fisher Banquet Room
San Francisco, CA 94158


8:00 am

Registration & Coffee

8:30 am

Welcome and Introduction to the Chemical Biology Consortium and UCSF

Barbara Mroczkowski, PhD, Michelle Arkin, PhD, Pamela Munster, MD, Charles Craik, PhD

8:45 am

Discovery and Characterization of Picomolar Inhibitors of WDR5

Taekyu Lee, PhD (Vanderbilt), William Tansey PhD (Vanderbilt)

9:30 am

Scaffold-based Discovery of Anti-Tumor Compounds

Gideon Bollag, PhD (Plexxikon)

10:00 am

Fingerprints for Immuno-Oncology Response

Adil Daud, MD (UCSF)

10:30 am

Coffee Break

11:00 am

Histone Deacetylase Inhibitors in the Clinic

Pamela Munster, MD (UCSF)

11:30 am

Attacking the Cell Surfaceome in Cancer

Jim Wells, PhD (UCSF)

12:00 pm


1:00 pm

Atypical Protein Kinases - From Mechanisms to Therapy

Natalia Jura, PhD (UCSF)

1:30 pm

Oncology Diagnostic Development in the Era of Genomics and Immunooncology

Mark Lackner, PhD, (IDEAYA Biosciences)

2:00 pm

STAT3 Decoys

Jennifer Grandis, MD (UCSF)

2:30 pm

Coffee Break

3:00 pm

Inducing Androgen Receptor Degradation By Targeting Molecular Chaperones

Jason Gestwicki, PhD (UCSF)

3:30 pm

Co-opting the Ubiquitin System for Therapeutic Benefit

Ingrid Wertz, PhD (Genentech)

4:00 pm

Poster Flash Talks

5:00 pm

Cocktails and Posters

6:30 pm

Meeting Adjourned


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