University of California San Francisco
Helen Diller Family Comprehensive Cancer Center

Breast Oncology Program Seminar

January 23, 2019, 8:30 am – 10:00 am

Mount Zion
2340 Sutter Street
Lurie Seminar Room
San Francisco, CA 94143

Michael Campbell, PhD, UCSF   >view speaker profile

"Painting Immune Landscapes of Breast Cancer"

Abstract: The emergence of immune oncology has offered a new toolbox to researchers and clinicians in breast cancer treatment, especially for breast cancer subtypes that lack targeted therapy such as triple-negative breast cancer. Immunotherapy harnesses the power of the body’s natural immune system to fight cancer, however, not all tumors respond in the same way to immunotherapy. Since some types of immune cells attack cancer, while others protect tumor cells from harm, a deeper understanding of immune cell infiltrates and their interactions with each other and with malignant cells is needed in order to efficiently harness the immune system and to begin to develop immunotherapy that’s custom-built based on an individual’s tumor immune microenvironment. In this presentation we will discuss some of the tools and techniques being used to characterize immune infiltrates in breast cancer, the immune landscape of DCIS and how it can be manipulated, and immune landscapes of invasive breast cancer in the context of immune checkpoint therapy.

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