University of California San Francisco
Helen Diller Family Comprehensive Cancer Center

Pediatric Malignancies Program Meeting

December 11, 2019, 8:00 am – 12:00 pm

Mission Bay
1450 3rd Street, HD-160
Bakar Auditorium
San Francisco, CA 94143

Aberrant Ras Signaling in Developmental Disorders and Pediatric Cancer

8:20 - 8:30 am

Welcome and Overview (Kevin Shannon)

8:30 - 9:10 am

Clinical Management of NF1 and Rasopathy Disorders (Alyssa Reddy)

9:10 - 9:40 am

Using isogenic iPSC lines to identify new therapeutic targets for JMML (Anna Hecht de Gutierrez)

9:40 - 10:10 am

Cytoplasmic Protein Granules Organize Kinase-Mediated Ras signaling (Asmin Tulpule)

10:10 - 10:30 am

Coffee Break

10:30 - 11:00 am

Role of RIT1 and LZTR1 Mutations in RASopathies and Malignancies (Pau Castel)

11:00 - 11:30 am

Mouse Models of Developmental Disorders Caused by Germline KRAS Mutations (Jasmine Wong)

11:30 am - 12:00 pm 

Targeting the Palmitoylation Cycle in NRAS Mutant Cancers (Kevin Shannon)


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