University of California San Francisco
Helen Diller Family Comprehensive Cancer Center

Center for Evolution and Cancer

The Center for Evolution and Cancer within the UCSF Helen Diller Family Comprehensive Cancer Center focused on the fundamental evolutionary dynamics that drive carcinogenesis, therapeutic resistance, and cancer susceptibility. From 2011 to 2016 the CEC brought together researchers from across the world to accelerate progress in cancer research, with the goal of employing evolutionarily informed approaches to advance cancer research, cancer prevention, and patient management.


Third International Biannual Evolution and Cancer Conference (IBECC)

December 10 - 13, 2015
Mission Bay Conference Center, UCSF

Theme: Evolutionary Tradeoffs and Clinical Consequences

Tradeoffs are pervasive in biological systems, and the evolutionary dynamics underlying cancer are no exception. The Third International Biannual Evolution and Cancer Conference (IBECC) explores the ways in which tradeoffs have shaped the evolution of cancer suppression systems and the role of tradeoffs in the progression of tumors from benign to malignant. A consideration of evolutionary tradeoffs can also help us to identify challenges and opportunities in cancer therapy and new horizons for cancer prevention.

We welcome scientists coming from different disciplines, including but not limited to oncology, cell biology, evolutionary biology and mathematics. Abstract submissions relating to the theme of evolutionary tradeoffs and clinical consequences are encouraged but submission on all evolution and ecology of cancer topics are welcome.


June 2015:

Special theme issue of The Royal Society's Philosophical Transactions: Cancer across life: Peto's paradox and the promise of comparative oncology
Compiled and edited by Joshua Schiffman, Carlo C. Maley, Leonard Nunney, Michael Hochberg and Matthew Breen.
June 2013:
View video highlights from the From Unicellularity to Multicellularity and Back Again: 2nd International Biannual Evolution and Cancer Conference
Feb 1, 2012:
Special issue of the journal Evolutionary Applications on Evolution and Cancer. >click here
The guest editors were Carlo Maley, Athena Aktipis, Michael Hochberg, Frederic Thomas and Ula Hibner. Articles were contributed by many of the CEC faculty. All papers are open access.