Conference 2011 Program

First Biannual international Evolution and Cancer Conference

June 3-5, 2011
University of California San Francisco, Mission Bay Campus

Register by May 25th

Hosts:
Center for Evolution and Cancer
Helen Diller Family Comprehensive Cancer Center

Topics:

• Evolution in neoplastic progression
• Evolution in therapeutic resistance
• Evolution of cancer suppression in multicellular organisms
• Social evolution in cancer
• Human evolution and cancer susceptibility

PDF version of agenda

9:00-10:00	Introduction to Evolution and Cancer
Carlo Maley	Introduction to the Center for Evolution and Cancer, Overview of the Conference, and the Basics of Evolution and Cancer
Robert Austin	Bacteria, Evolution, and Cancer
Craig McClain	Opportunities from NESCent
10:00-11:00	break
11:00-12:00	Introduction to Evolution and Cancer II
Robert Gatenby	Somatic Evolution of Cancer: Location, Location
David Haussler	Cancer Genomics and the TCGA Project
Robert Getzenberg	Micro-environmental Stress and the Development of Drug Resistance
12:00-1:00	lunch (provided)
1:00-2:00	Intragenomic Conflict Tutorial and Brainstorming Session
David Haig	Are Cancer Rates Higher in Mammals than Other Vertebrates?
2:00-2:30	break
2:30-3:50	Cancer as a Disease of the Evolution of Multicellularity
Nicole King	The Unicellular Ancestry of Animal Multicellularity
Aurora Nedelcu	Evolutionary Vulnerabilities in Cancer: Insights from Unicellular Lineages
Andrei Seluanov	Evolution of Anticancer Mechanisms in Rodents
Kathleen Sprouffske	An Evolutionary Explanation for the Presence of Cancer Non-Stem Cells in Neoplasms
3:50-4:40	break
4:40-6:00	Measuring Evolution in Neoplastic Progression
Doug Brash	Clonal Expansion of p53-Mutant Stochastic Stem Cells in the Skin
Henry Heng	Punctuated Cancer Evolution: Tracing Genome Replacement and Dynamics
Rumen Kostadinov	Clonal Expansion during Neoplastic Progression in Barrett’s Esophagus
Daniel Fisher	What Can One Learn about Their Evolutionary Dynamics from Age Incidence of Cancers?
6:00	dinner on your own with potential collaborators
8:00	Keynote Public Lecture Robert Gatenby - Evolutionary Strategies for Cancer Therapy

9:00-10:00	The Evolutionary Theory of Cancer I
Frank McCormick	t.b.a.
Alexander Anderson	How Do Interactions Modulate Heterogeneity in Cancer Progression and Drug Resistance?
David Basanta	Tumor Cells Are Not Alone: How the Cancer Ecology Influences the Evolutionary Dynamics in Cancer
10:00-11:00	break
11:00-12:00 noon	The Evolutionary Theory of Cancer II
Len Nunney	The Evolution of Cancer Genes: When Do We Expect to See Positive Selection?
Jasmine Foo	Stochastic Dynamics of Cancer Initiation
Ricard Sole	Evolution towards Unstable Thresholds in Model Cancer Populations
12:00-1:00	lunch (provided)
1:00-3:00	Somatic Evolution in the Clinic
Darryl Shibata	Reconstructing Human Tumor Histories by Comparing Genomes from Different Parts of the Same Cancer
Brian Reid	Multilevel Evolution and Neoplastic Progression in Barrett’s Esophagus
Jose Costa	The Evolutionary Theory of Cancer: An Heuristic and Practical Tool in the Clinic
Stephen Quake	t.b.a.
James DeGregori	Tumor Suppression by Modulating Stem Cell Fitness
3:00-4:00	break
4:00-6:00	Cooperation, Conflict, and Co-evolution
John Pepper	Cooperationong Cancer Cells as a Target for Intervention
John Tooby	Cancer as the Product of Two Host-Parasite Coevolutionary Races
AJ Figueredo	Cancer and Life History Theory
Steve Neuberg	Barbarian Horde, Competing Gangs, or…?  Alternative Social Group Metaphors and Their Implications
Paul Ewald	t.b.a.
6:45	Speed Team Building - Steve Neuberg
8:00	speaker and sponsor dinner

9:00-9:40	Robert Hiatt - Life-Course Epidemiology of Breast Cancer
9:40-10:20	Reproductive Cancers and Human Evolution I
Beverly Strassman	The Biology of Menstruation in the Absence of Contraception: Implications for Breast Cancer
Boyd Eaton	Breast Cancer and Human Evolution
10:20-11:00	break
11:00-12:00	Reproductive Cancers and Human Evolution II
Athena Aktipis	Breast Cancer from a Life History Perspective
Martie Haselton	Ovulation and Human Social Behavior
Karen Weihs	Social Relationship Predictors of Well-Being in Breast Cancer Patients: Is Oxytocin Involved?
12:00-1:30	lunch (provided)
1:30-2:30	Cancer in Evolutionary Medicine
Randolph Nesse	How Evolution Inspires Good Questions about Cancer
Virginia Kwan	Psychological Barriers to Evolutionary Thinking in Cancer
Ed Hagen	Drugs are Bad…for Pathogens: Testing an Alternative to the Reward Model of Tobacco Use and Its Implications for Smoking Cessation
2:30-3:30	break
3:30-4:30	Panel on Grant Writing and Team Building for Cancer Research
4:30-5:30	Breakout Groups for Grant Development
5:30	conference ends