University of California San Francisco
Helen Diller Family Comprehensive Cancer Center

Conference 2011 Program

First Biannual international Evolution and Cancer Conference

June 3-5, 2011
University of California San Francisco, Mission Bay Campus

Register by May 25th

Center for Evolution and Cancer
Helen Diller Family Comprehensive Cancer Center


  • Evolution in neoplastic progression
  • Evolution in therapeutic resistance
  • Evolution of cancer suppression in multicellular organisms
  • Social evolution in cancer
  • Human evolution and cancer susceptibility


PDF version of agenda

9:00-10:00 Introduction to Evolution and Cancer
Carlo Maley Introduction to the Center for Evolution and Cancer, Overview of the Conference, and the Basics of Evolution and Cancer
Robert Austin Bacteria, Evolution, and Cancer
Craig McClain Opportunities from NESCent
10:00-11:00 break
11:00-12:00 Introduction to Evolution and Cancer II
Robert Gatenby Somatic Evolution of Cancer: Location, Location
David Haussler Cancer Genomics and the TCGA Project
Robert Getzenberg Micro-environmental Stress and the Development of Drug Resistance
12:00-1:00 lunch (provided)
1:00-2:00 Intragenomic Conflict Tutorial and Brainstorming Session
David Haig Are Cancer Rates Higher in Mammals than Other Vertebrates?
2:00-2:30 break
2:30-3:50 Cancer as a Disease of the Evolution of Multicellularity
Nicole King The Unicellular Ancestry of Animal Multicellularity
Aurora Nedelcu Evolutionary Vulnerabilities in Cancer: Insights from Unicellular Lineages
Andrei Seluanov Evolution of Anticancer Mechanisms in Rodents
Kathleen Sprouffske An Evolutionary Explanation for the Presence of Cancer Non-Stem Cells in Neoplasms
3:50-4:40 break
4:40-6:00 Measuring Evolution in Neoplastic Progression
Doug Brash Clonal Expansion of p53-Mutant Stochastic Stem Cells in the Skin
Henry Heng Punctuated Cancer Evolution: Tracing Genome Replacement and Dynamics
Rumen Kostadinov Clonal Expansion during Neoplastic Progression in Barrett’s Esophagus
Daniel Fisher What Can One Learn about Their Evolutionary Dynamics from Age Incidence of Cancers?
6:00 dinner on your own with potential collaborators
8:00 Keynote Public Lecture
Robert Gatenby - Evolutionary Strategies for Cancer Therapy


9:00-10:00 The Evolutionary Theory of Cancer I
Frank McCormick t.b.a.
Alexander Anderson How Do Interactions Modulate Heterogeneity in Cancer Progression and Drug Resistance?
David Basanta Tumor Cells Are Not Alone: How the Cancer Ecology Influences the Evolutionary Dynamics in Cancer
10:00-11:00 break
11:00-12:00 noon The Evolutionary Theory of Cancer II
Len Nunney The Evolution of Cancer Genes: When Do We Expect to See Positive Selection?
Jasmine Foo Stochastic Dynamics of Cancer Initiation
Ricard Sole Evolution towards Unstable Thresholds in Model Cancer Populations
12:00-1:00 lunch (provided)
1:00-3:00 Somatic Evolution in the Clinic
Darryl Shibata Reconstructing Human Tumor Histories by Comparing Genomes from Different Parts of the Same Cancer
Brian Reid Multilevel Evolution and Neoplastic Progression in Barrett’s Esophagus
Jose Costa The Evolutionary Theory of Cancer: An Heuristic and Practical Tool in the Clinic
Stephen Quake t.b.a.
James DeGregori Tumor Suppression by Modulating Stem Cell Fitness
3:00-4:00 break
4:00-6:00 Cooperation, Conflict, and Co-evolution
John Pepper Cooperationong Cancer Cells as a Target for Intervention
John Tooby Cancer as the Product of Two Host-Parasite Coevolutionary Races
AJ Figueredo Cancer and Life History Theory
Steve Neuberg Barbarian Horde, Competing Gangs, or…?  Alternative Social Group Metaphors and Their Implications
Paul Ewald t.b.a.
6:45 Speed Team Building - Steve Neuberg
8:00 speaker and sponsor dinner


9:00-9:40 Robert Hiatt - Life-Course Epidemiology of Breast Cancer
9:40-10:20 Reproductive Cancers and Human Evolution I
Beverly Strassman The Biology of Menstruation in the Absence of Contraception: Implications for Breast Cancer
Boyd Eaton Breast Cancer and Human Evolution
10:20-11:00 break
11:00-12:00 Reproductive Cancers and Human Evolution II
Athena Aktipis Breast Cancer from a Life History Perspective
Martie Haselton Ovulation and Human Social Behavior
Karen Weihs Social Relationship Predictors of Well-Being in Breast Cancer Patients: Is Oxytocin Involved?
12:00-1:30 lunch (provided)
1:30-2:30 Cancer in Evolutionary Medicine
Randolph Nesse How Evolution Inspires Good Questions about Cancer
Virginia Kwan Psychological Barriers to Evolutionary Thinking in Cancer
Ed Hagen Drugs are Bad…for Pathogens: Testing an Alternative to the Reward Model of Tobacco Use and Its Implications for Smoking Cessation
2:30-3:30 break
3:30-4:30 Panel on Grant Writing and Team Building for Cancer Research
4:30-5:30 Breakout Groups for Grant Development
5:30 conference ends