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Gastrointestinal Oncology UCSF
Triplet Therapy Effective in BRAF-mutant mCRC

Triplet Therapy Effective in BRAF-mutant mCRC

June 8, 2015

The combination of dabrafenib (Tafinlar), trametinib (Mekinist), and panitumumab (Vectibix) demonstrated an objective response rate (ORR) of 26% and a median progression-free survival (PFS) of 4.1 months in pretreated patients with BRAFV600E-mutated metastatic colorectal cancer (mCRC), according to findings from a phase I/II study presented at the 2015 ASCO Annual Meeting.

 

Dr. Venook Discusses Implications of the 80405 Study

Dr. Venook Discusses Implications of the 80405 Study

June 28, 2014

Alan P. Venook, MD discusses implications from the CALGB/SWOG 80405 trial on the targeted therapies administered in colorectal cancer. - See more at: http://www.onclive.com/conference-coverage/world-GI-2014/Dr-Venook-Discusses-Implications-of-the-80405-Study.

 

 

Environmental Carcinogens Leave Distinctive Genetic Imprints in Tumors

Environmental Carcinogens Leave Distinctive Genetic Imprints in Tumors

November 4, 2014

Genetically engineering tumors in mice, a technique that has dominated cancer research for decades, may not replicate important features of cancers caused by exposure to environmental carcinogens, according to a new study led by UC San Francisco scientists.

 

Kelley Receives Leadership Award from the National Cancer Institute

Kelley Receives Leadership Award from the National Cancer Institute

September 4, 2014

Katie Kelley, MD, a gastrointestinal oncologist at UC San Francisco, has received the 2014 Cancer Clinical Investigator Team Leadership Award from the National Cancer Institute (NCI).

Notable Progress Against Colorectal Cancer Shown in 10-Year National Study

Notable Progress Against Colorectal Cancer Shown in 10-Year National Study

June 1, 2014

Research led by a UC San Francisco investigator establishes a new benchmark in the treatment of patients with metastatic colorectal cancer and sets a new expectation for how long patients can live with the particularly lethal disease.

Genetic Discovery Could Help Guide Doctors' Treatment of Bladder Cancers

Genetic Discovery Could Help Guide Doctors' Treatment of Bladder Cancers

October 16, 2013

A UC San Francisco-led team of scientists has discovered that a gene mutation found in some bladder cancers is indicative of low-risk tumors that are unlikely to recur or progress after surgery.

Study Sheds Light on How Pancreatic Cancer Begins

Study Sheds Light on How Pancreatic Cancer Begins

November 29, 2012

A diagnosis of pancreatic cancer is particularly devastating since the prognosis for recovery is usually poor, with the cancer most often not detected until late stages.

Research Offers New Hope for HIV/AIDS Patients with Cancer

Research Offers New Hope for HIV/AIDS Patients with Cancer

August 21, 2012

A proposed new treatment to help HIV/AIDS patients suffering from Kaposi’s sarcoma, the most common form of cancer in people with HIV, is now one step closer to becoming a reality.

Free Seminar Targets Patients with Colorectal Cancer

October 17, 2009

UCSF will host a free educational seminar on Saturday, Oct. 31 aimed at individuals with colorectal cancer -- a disease that kills nearly 50,000 Americans each year but is often curable if caught early. The seminar, "Conversations about Colorectal Cancer," will offer patients the opportunity ...

GI Oncology Group Honored for Outstanding Patient Care

July 1, 2009

Members of UCSF's Gastrointestinal (GI) Oncology group are the inaugural recipients of the Helen Diller Family Quality Award, an honor that recognizes exceptional commitment to providing superior patient care. The group, led by gastrointestinal cancer expert Alan Venook, MD, was named the top performer in ...