University of California San Francisco
Helen Diller Family Comprehensive Cancer Center
Year in Review: 2018

Year in Review: 2018

December 12, 2018

Precision medicine, immunotherapy, and population health led the news at the UCSF Helen Diller Family Comprehensive Cancer Center in 2018.  Whether through expediting drug discovery, tailoring genomic sequencing, or expanding palliative care, our UCSF cancer community remained committed to improving outcomes for every cancer ...
Cancer Researchers ID 'Achilles Heel' of Drug-Resistant Tumors

Cancer Researchers ID 'Achilles Heel' of Drug-Resistant Tumors

November 26, 2018

UC San Francisco scientists have figured out why some lung cancers become drug-resistant after initially responding to targeted therapies. In the process, they devised a new two-pronged approach that yields an effective treatment for these cancers in the laboratory and holds tremendous promise for the ...
New Method Of Breast Reconstruction May Reduce Pain For Some Cancer Survivors

New Method Of Breast Reconstruction May Reduce Pain For Some Cancer Survivors

November 20, 2018

For nearly four decades, the main option for breast reconstruction for women who had to undergo a mastectomy was to place implants under the main chest muscle – a procedure that often results in chronic pain and muscle weakness in the chest and arms. Hani ...
Small Molecule Discovery Core combines high-throughput biology and medicinal chemistry to accelerate drug discovery

Small Molecule Discovery Core combines high-throughput biology and medicinal chemistry to accelerate drug discovery

November 15, 2018

The goal of the Small Molecule Discovery Core (SMD) is to help the Cancer Center and other investigators initiate drug discovery and chemical biology projects for their most innovative and exciting new targets. Faculty co-directors Adam Renslo, PhD and Michelle Arkin, PhD, both of UCSF’s ...
New 'SLICE' Tool Can Massively Expand Immune System's Cancer-Fighting Repertoire

New 'SLICE' Tool Can Massively Expand Immune System's Cancer-Fighting Repertoire

November 15, 2018

Immunotherapy can cure some cancers that until fairly recently were considered fatal. In addition to developing drugs that boost the immune system’s cancer-fighting abilities, scientists are becoming expert at manipulating a patient’s own immune cells, turning them into cancer-killing armies. But cancers have tricks ...
Get To Know: Tung Nguyen, MD

Get To Know: Tung Nguyen, MD

November 15, 2018

Dr. Tung Nguyen is the Stephen J. McPhee, MD Endowed Chair in General Internal Medicine and Professor of Medicine at the University of California, San Francisco (UCSF). A general internist with a large panel of Asian American patients, Dr. Nguyen teaches medical students and residents ...
Less Surveillance Needed for Simple Ovarian Cysts

Less Surveillance Needed for Simple Ovarian Cysts

November 13, 2018

Simple ovarian cysts are extremely common in women and do not require additional ultrasound surveillance or surgical removal, according to a new study of more than 72,000 women and close to 119,00 pelvic ultrasound exams over a dozen years. The study, a collaboration between UC San Francisco and Kaiser Permanente Washington, found that simple ...
Cognitive Decline After Radiation Therapy for Brain Tumors Might Be Prevented By Temporarily Shutting Down Immune Response

Cognitive Decline After Radiation Therapy for Brain Tumors Might Be Prevented By Temporarily Shutting Down Immune Response

November 13, 2018

Treating brain tumors comes at a steep cost, especially for children. More than half of patients who endure radiation therapy for these tumors experience irreversible cognitive decline, a side-effect that has particularly damaging consequences for younger patients. Up to now, scientists had been unable to ...

"Orphan" RNAs Make Cancer Deadlier, But Potentially Easier to Diagnose

November 7, 2018

Scientists have long known that cancer can hijack a cell’s existing regulatory circuitry and transform healthy cells into deadly malignancies. But a new discovery from UC San Francisco demonstrates that cancer is more than just a mutineer that seizes control of the cell’s administrative operations ...
As teen use of Juul soars, doctors ask, what's really in these e-cigs?

As teen use of Juul soars, doctors ask, what's really in these e-cigs?

November 1, 2018

Tobacco research from UCSF is central to a growing understanding of the dangers of e-cigarettes and vaping products, as highlighted in this feature from NBC News.  Dr. Mark Rubinstein, who studies nicotine dependence in adolescents at the University of California San Francisco, led the ...