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Cancer Research Shows Promise of New Drugs

Cancer Research Shows Promise of New Drugs

February 22, 2012

Uncovering the network of genes regulated by a crucial molecule involved in cancer called mTOR, which controls protein production inside cells, researchers at the University of California, San Francisco (UCSF) have discovered how a protein “master regulator” goes awry, leading to metastasis, the fatal step of cancer.

Vigorous Exercise Linked to Gene Activity in Prostate

Vigorous Exercise Linked to Gene Activity in Prostate

February 1, 2012

Scientists at the University of California, San Francisco (UCSF) have identified nearly 200 genes in the healthy prostate tissue of men with low-grade prostate cancer that may help explain how physical activity improves survival from the disease.

UCSF School of Medicine Leaders Explore Bioinformatics in Research, Patient Care and Education

UCSF School of Medicine Leaders Explore Bioinformatics in Research, Patient Care and Education

January 30, 2012

In the world of bioinformatics, the rush is on to extract gold from a data mine.

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New Lung Cancer Test Predicts Survival

January 26, 2012

In the two largest clinical studies ever conducted on the molecular genetics of lung cancer, an international team led by scientists at the University of California, San Francisco (UCSF) has demonstrated that an available molecular test can predict the likelihood of death from early-stage lung cancer more accurately than conventional methods.

Team Finds New Way to Image Brain Tumors and Predict Recurrence

Team Finds New Way to Image Brain Tumors and Predict Recurrence

January 23, 2012

After people with low-grade glioma, a type of brain cancer, undergo neurosurgery to remove the tumors, they face variable odds of survival — depending largely on how rapidly the cancer recurs.

Chancellor Presents Proposal to Secure UCSF’s Future

Chancellor Presents Proposal to Secure UCSF’s Future

January 19, 2012

UCSF Chancellor Susan Desmond-Hellmann, MD, MPH, proposed to the University of California Regents on Jan. 19 that a small working group be formed to help UCSF explore options to secure its financial future so it can realize its vision to become the world’s preeminent health sciences innovator.

Some Breast Cancer Spread May Be Triggered By Targetable Protein, Study Shows

Some Breast Cancer Spread May Be Triggered By Targetable Protein, Study Shows

January 17, 2012

Cancers rarely are deadly unless they evolve the ability to grow beyond the tissues in which they first arise.

Prostate Cancer Screenings at VA Hospitals Don’t Follow Guidelines for Elderly, Study Says

Prostate Cancer Screenings at VA Hospitals Don’t Follow Guidelines for Elderly, Study Says

January 10, 2012

Veterans Affairs hospitals screen elderly men with limited life expectancies for prostate cancer at surprisingly high rates, even though guidelines recommend against such screening, according to a study led by a physician at the UCSF-affiliated San Francisco VA Medical Center (SFVAMC).

Tobacco Company Misrepresented Danger from Cigarettes, Study Finds

Tobacco Company Misrepresented Danger from Cigarettes, Study Finds

January 6, 2012

A new UCSF analysis of tobacco industry documents shows that Philip Morris USA manipulated data on the effects of additives in cigarettes, including menthol, obscuring actual toxicity levels and increasing the risk of heart, cancer and other diseases for smokers.

UCSF Cancer-Drug Spinoff Acquired for $190M

UCSF Cancer-Drug Spinoff Acquired for $190M

December 23, 2011

A cancer drug company founded by UCSF Professor Kevan Shokat, PhD, has been acquired by Japan-based Takeda Pharmaceuticals in an effort to add two novel drug projects to Takeda’s pipeline of potential oncology therapies.