News

UCSF Establishes Quantitative Biosciences Institute

UCSF Establishes Quantitative Biosciences Institute

March 17, 2016

UC San Francisco today announced the establishment of the Quantitative Biosciences Institute (QBI). The mission of QBI, located on the UCSF Mission Bay health sciences campus, is to drive forward the application of computation, mathematics, and statistics toward a deeper understanding of complex problems in biology, with the ultimate goal of developing new treatments for disease.

UCSF Research Suggests New Model for Cancer Metastasis

UCSF Research Suggests New Model for Cancer Metastasis

March 17, 2016

Scientists at UC San Francisco have been able to directly observe, for the first time, how invasive cancer cells create a beachhead as they migrate to the lung in a mouse model of metastatic cancer. What they saw was utterly surprising: early “pioneer” cancer cells that lodge in the lung generally die, but first they shed zombie-like particles that move around on their own and get gobbled up by waves of immune cells.

Triple-Negative Breast Cancers Depend on Fat as Fuel, Research Shows

Triple-Negative Breast Cancers Depend on Fat as Fuel, Research Shows

March 7, 2016

The most intractable common form of breast cancer might in most cases be treatable by drugs that target fat metabolism, according to UC San Francisco researchers who discovered the tumors’ frequent dependence on fat as an energy source, and then successfully treated human breast tumors that they transplanted and grew in mice.

VP Biden Discusses Cancer Moonshot with UCSF Experts

VP Biden Discusses Cancer Moonshot with UCSF Experts

March 2, 2016

Vice President Joe Biden and his wife Jill Biden, PhD, visited UC San Francisco on Saturday, February 27, to discuss the administration’s national “Moonshot” initiative to improve cancer outcomes in the next decade.

Trever Bivona: Finding the Pathways to Better Cancer Treatment

Trever Bivona: Finding the Pathways to Better Cancer Treatment

March 2, 2016

Making the connections between molecules in the lab and their actions in a patient’s cancer led Trever Bivona to pursue both doctoral and medical training. Now a practicing oncologist and researcher at UC San Francisco, Bivona’s studies are driven by a simple question: Which protein mutations are relevant to actually improving treatments?

UC Health Pledges Improved Data-Sharing with Patients at White House Precision Medicine Summit

UC Health Pledges Improved Data-Sharing with Patients at White House Precision Medicine Summit

February 26, 2016

University of California Health committed to enabling patients to access and share their own health data, joining more than 40 other organizations that made various commitments to advance precision medicine during a White House summit this week.

Using Big Data to Chart Cancer’s Hidden Genetic Weaknesses

Using Big Data to Chart Cancer’s Hidden Genetic Weaknesses

February 24, 2016

"As we refine our understanding of how patients’ mutations affect larger biological networks, that’s going to improve doctors’ predictive power in a clinical setting."
-- Nevan Krogan, PhD

BRCA Clinics Expand Further Beyond Breast Cancer

BRCA Clinics Expand Further Beyond Breast Cancer

February 22, 2016

from the Wall Street Journal:  A new clinic in San Francisco is opening with an unusual mission: to provide care for people affected by mutations in two particular genes linked to a high risk of cancer.

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Tricked-Out Immune Cells Could Attack Cancer, Spare Healthy Cells

January 28, 2016

UC San Francisco scientists have created a new class of highly customizable biological sensors that can be used to form “logic gates” inside cells of the immune system, giving these cells the capability to home in on and kill a wide range of cancer cells while preventing them from attacking normal tissue.

For Breast Cancer Patients, Never Too Late To Quit Smoking

For Breast Cancer Patients, Never Too Late To Quit Smoking

January 27, 2016

Documenting that it’s never too late to quit smoking, a large study of breast cancer survivors has found that those who quit smoking after their diagnosis had a 33 percent lower risk of death as a result of breast cancer than those who continued to smoke.