News

Targeting a Key Driver of Cancer: Part III

Targeting a Key Driver of Cancer: Part III

July 7, 2014

Pharmaceutical, biotech and academic laboratories long have tried to develop drugs to target Ras. Most of the efforts focused on K-Ras, which is one of the three different types, or “isoforms,” of Ras – the others are N-Ras and H-Ras – and is the most

Targeting a Key Driver of Cancer: Part II

Targeting a Key Driver of Cancer: Part II

June 27, 2014

When Todd and Lisa Harris were informed that their 10-month-old son Evan had cancer, they were very upset, but they also felt as if a weight had been lifted. “At least now we had an answer, albeit an extremely painful one, and a path forward,” Lisa Harris said about her son’s diagnosis at the time.

How a Thick

How a Thick "Sugar Coating" on Cells May Drive Aggressive Cancers

June 25, 2014

A research team led by UC San Francisco scientists has shown that cancer-induced structural changes in a sugary coating ensheathing cells can promote mechanical interactions that fuel tumor growth and metastasis.
 
Targeting a Key Driver of Cancer

Targeting a Key Driver of Cancer

June 18, 2014

It’s one of the most common and deadly drivers of cancer, yet it has eluded any drug therapies for decades.  Now, buoyed by recent research breakthroughs and funding support, scientists are pushing harder than ever to target what has been called "undruggable."

Longer Telomeres Linked to Risk of Brain Cancer

Longer Telomeres Linked to Risk of Brain Cancer

June 8, 2014

New genomic research led by UC San Francisco scientists reveals that two common gene variants that lead to longer telomeres, the caps on chromosome ends thought by many scientists to confer health by protecting cells from aging, also significantly increase the risk of developing the deadly brain cancers known as gliomas.
 
Notable Progress Against Colorectal Cancer Shown in 10-Year National Study

Notable Progress Against Colorectal Cancer Shown in 10-Year National Study

June 1, 2014

Research led by a UC San Francisco investigator establishes a new benchmark in the treatment of patients with metastatic colorectal cancer and sets a new expectation for how long patients can live with the particularly lethal disease.

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UCSF to Present Advances in Prostate Cancer Treatment, Immunotherapy at Major Cancer Meeting

May 29, 2014

From prostate cancer to immunotherapy to genetic testing, UC San Francisco research is providing new insights and aiding in the development of new treatment strategies for cancer.

Peter Walter Receives Shaw Prize in Life Science and Medicine

Peter Walter Receives Shaw Prize in Life Science and Medicine

May 27, 2014

A UC San Francisco professor of biochemistry and biophysics has received Asia’s highest scientific honor, the 2014 Shaw Prize in Life Science and Medicine, for his groundbreaking discovery of a system that makes "life and death decisions" for the cell.

E-Cigarettes Expose People to More than 'Harmless' Water Vapor and Should be Regulated, UCSF Scientists Find

E-Cigarettes Expose People to More than 'Harmless' Water Vapor and Should be Regulated, UCSF Scientists Find

May 13, 2014

In a major scientific review of research on e-cigarettes, UC San Francisco scientists found that industry claims about the devices are unsupported by the evidence to date, including claims that e-cigarettes help smokers quit. 
 
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New Cancer Immunotherapy Aims Powerful T Cells Against Tumors

May 12, 2014

Deadly skin cancers in mice shrank in response to a new treatment that may complement other "immunotherapies" developed recently to boost the body’s own defenses against disease threats, according to a new study published by UC San Francisco researchers in the May 2014 edition of the Journal of Experimental Medicine.