In a Human Virus, New Method to ID MicroRNA Targets Proves Its Value

January 20, 2009

MicroRNAs are a very important, newly recognized type of molecule naturally encoded within the human genome. MicroRNAs, or miRNAs, help determine which gene products are produced in a cell. Some miRNAs have been found to act abnormally in cancers, and a few years ago miRNAs ...

UCSF Study Reveals Roots of Endothelial Cell Development

January 15, 2009

A team of UCSF researchers has for the first time identified a genomic regulatory mechanism behind the formation of the cells that line the interior of blood vessels. Their findings, published in the Dec. 12, 2008, issue of Cell, not only advance the study of ...

Study of Powerful Genes and Cancer Points to Vitamin D, Inflammation

January 13, 2009

Thanks to researchers like UCSF's Allan Balmain, PhD, today's accounts of research on genes and cancer are less likely to resemble a tale of blind men describing an elephant. Balmain is at the forefront among those helping other researchers to see more deeply into how ...

Looking Far Afield for Pancreas Cancer Clues

January 12, 2009

Consider the lab mouse. The rodent is used to model tumor growth in countless studies of genes and cancer. About 99 percent of mouse genes also appear in humans. Mouse and human also are similar when one compares the DNA code within these genes. Mice ...

UCSF Researchers Use New Tools to Move In on Cancer Susceptibility Genes

January 12, 2009

UCSF researchers have used a new strategy to study inherited susceptibility for skin cancer in mice. In the process, they have identified a network of genes that may play a key role in controlling this susceptibility. The technique, the scientists say, could be used to ...

Colon Cancer and Heredity

January 6, 2009

In an audio interview, genetic counselor Amie Blanco of the Cancer Risk Program at the UCSF Helen Diller Family Comprehensive Cancer Center discusses familial risk for colon cancer, as well as screening and prevention for this disease. Ms. Blanco is interviewed by Andrew Schorr in ...

American Cancer Society Recognizes UCSF's Glantz as International Tobacco Control Leader

December 18, 2008

he American Cancer Society recently has named Stanton Glantz, PhD, professor of medicine and director of the UCSF Center for Tobacco Control Research and Education, as the lead recipient of the 2009 Luther L. Terry Awards for Exemplary Leadership in Tobacco Control. The award -- ...

Culprit in Eye Cancer Identified, Drug Development Begins

December 16, 2008

Very soon, there may be new hope for patients with a deadly cancer that strikes the eye. The cancer is uveal melanoma. Targeting the disease has proved elusive, and treatment has been unsatisfactory. Now, researchers led by UCSF skin pathologist Boris Bastian, MD, have identified ...

Search for Genetic Clues to Breast Cancer in Hispanic Women

December 9, 2008

Hispanic women in the US are less likely to get breast cancer than non-Hispanic, white women. But it's not clear why. And despite the lower incidence, breast cancer is still the most common cancer in Hispanic women. For all women, both genes and environment are ...

Howard Hughes Awardees Will Use UCSF Cell Discovery to Target Cancer

December 5, 2008

The discovery of a basic life-and-death response within our bodies' cells might prove to be the basis for a new cancer-fighting strategy. That's the premise behind a new $4 million award from the Howard Hughes Medical Institute (HHMI) to an all-star team of researchers headed ...