News

Rare Melanoma Carries Unprecedented Burden of Mutations

Rare Melanoma Carries Unprecedented Burden of Mutations

September 7, 2015

A rare, deadly form of skin cancer known as desmoplasmic melanoma (DM) may possess the highest burden of gene mutations of any cancer, suggesting that immunotherapy may be a promising approach for treatment, according to an international team led by UC San Francisco scientists.

Genetic Makeup May Make Radiation Riskier for Pediatric Cancer Patients

Genetic Makeup May Make Radiation Riskier for Pediatric Cancer Patients

September 3, 2015

Genetic vulnerabilities associated with childhood cancers may make children undergoing radiation therapy more susceptible than adults to secondary cancers, according to novel insights from researchers at UC San Francisco.

Drug for Fungal Infections in Lung Transplant Recipients Increases Risk for Skin Cancer, Even Death

Drug for Fungal Infections in Lung Transplant Recipients Increases Risk for Skin Cancer, Even Death

September 3, 2015

Voriconazole, a prescription drug commonly used to treat fungal infections in lung transplant recipients, significantly increases the risk for skin cancer and even death, according to a new study by UC San Francisco researchers. The team recommends physicians consider patient-specific factors that could modify the drug’s risks and benefits, when providing care.

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DNA-Guided 3-D Printing of Human Tissue is Unveiled

September 1, 2015

A UCSF-led team has developed a technique to build tiny models of human tissues, called organoids, more precisely than ever before using a process that turns human cells into a biological equivalent of LEGO bricks.

Mammary Gland Is Shaped by Adaptive Immune System During Development

Mammary Gland Is Shaped by Adaptive Immune System During Development

August 27, 2015

In experiments with mouse tissue, UC San Francisco researchers have discovered that the adaptive immune system, generally associated with fighting infections, plays an active role in guiding the normal development of mammary glands, the only organs--in female humans as well as mice--that develop predominately after ...
Survivors of Childhood Cancer Have High-Risk of Recurrent Stroke

Survivors of Childhood Cancer Have High-Risk of Recurrent Stroke

August 26, 2015

Most people assume strokes only happen to octogenarians, but recent evidence suggests that survivors of childhood cancer have a high risk of suffering a stroke at a surprisingly young age.

Emmanuelle Passegué: Making Better Blood

Emmanuelle Passegué: Making Better Blood

August 26, 2015

Emmanuelle Passegué’s passion for blood is focused on rejuvenation and longer life.

Tool Boosts Accuracy in Assessing Breast Cancer Risk

Tool Boosts Accuracy in Assessing Breast Cancer Risk

August 19, 2015

A national risk model that gauges a woman’s chance of developing breast cancer has been refined to give a more accurate assessment. 

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Common Class of ‘Channel Blocking’ Drugs May Find a Role in Cancer Therapy

August 10, 2015

http://profiles.ucsf.edu/yuhnung.jan#toc-id2

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California Initiative to Advance Precision Medicine Announces Funding for 2 Projects

August 3, 2015

Two demonstration projects that aim to yield quick results for patients have been selected by the new California Initiative to Advance Precision Medicine, a public-private effort launched by Governor Edmund G. Brown Jr.