University of California San Francisco
Helen Diller Family Comprehensive Cancer Center
UCSF Researchers Identify Unique Genetic Alterations in Brain Tumors Occurring After Radiation

UCSF Researchers Identify Unique Genetic Alterations in Brain Tumors Occurring After Radiation

September 14, 2018

For many common childhood cancers, radiation therapy can be an effective, even curative, treatment. However, long-term survivors are at risk for developing new, or secondary, cancers as a consequence of radiation, sometimes decades later.  Children with cancers like medulloblastoma and craniopharyngioma are likely to receive intracranial radiation therapy as part ...
Scientists Map Interactions between Head and Neck Cancer and HPV Virus

Scientists Map Interactions between Head and Neck Cancer and HPV Virus

September 13, 2018

Human papillomavirus (HPV) is widely known to cause nearly all cases of cervical cancer. However, you might not know that HPV also causes 70 percent of oropharyngeal cancer, a subset of head and neck cancers that affect the mouth, tongue, and tonsils. Although vaccines that ...
Researchers Unlock Secret of Deadly Brain Cancer's

Researchers Unlock Secret of Deadly Brain Cancer's "Immortality"

September 10, 2018

UC San Francisco researchers have discovered how a mutation in a gene regulator called the TERTpromoter — the third most common mutation among all human cancers and the most common mutation in the deadly brain cancer glioblastoma — confers “immortality” on tumor cells, enabling the unchecked cell ...
Mutations, Drugs Drive Cancer by Blurring Growth Signals

Mutations, Drugs Drive Cancer by Blurring Growth Signals

September 6, 2018

Genetic mutations in a form of non–small cell lung cancer (NSCLC) may drive tumor formation by blurring cells’ perception of key growth signals, according to a new laboratory study published Aug. 31, 2018, in Science. The research, led by UC San Francisco researchers, could have important ...
Tailored Drug Cocktails Offer Hope to Kids with Aggressive Brain Tumors

Tailored Drug Cocktails Offer Hope to Kids with Aggressive Brain Tumors

August 29, 2018

UCSF Benioff Children’s Hospitals are harnessing next-generation genomic technology to develop individualized drug cocktails in a new trial for children with a type of malignant brain tumor. This precision-medicine approach offers a new strategy in the treatment for high-grade glioma, an intractable brain cancer in ...
UCSF Benioff Children's Hospitals will 'Be Gold' in September for Pediatric Cancer Awareness

UCSF Benioff Children's Hospitals will 'Be Gold' in September for Pediatric Cancer Awareness

August 29, 2018

Each year, nearly 16,000 U.S. children and teens are diagnosed with cancer. But only 4 percent of federal cancer research funding is earmarked to develop new treatments and cures for children battling this heartbreaking disease – an amount that is far below what is actually ...