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Helen Diller Family Compr Cancer Ctr
DONALD I. ABRAMS, MD

Professor, Clinical Medicine, UCSF; Chief, Hematology-Oncology, San Francisco General Hospital; Director of Clinical Programs, Osher Center for Integrative Medicine

CONTACT

(415) 353-7720 (appts)
(415) 502-2991 (fax)

Box 0874, UCSF; San Francisco, CA 94143-0874

additional websites:

UCSF Physician Referral Directory

EDUCATION

Brown University, Providence, RI, AB, 1972, Molecular Biology
Stanford Univ. School of Medicine, Stanford, CA, MD, 1977, Medicine
Kaiser Foundation Hospital, San Francisco, CA, 1980, Internal Medicine
Cancer Research Institute, UCSF, 1983, Hematology/Oncology
University of Arizona, Fellowship, Tucson, AZ, 2004, Integrative Medicine

PROFESSIONAL EXPERIENCE

July 1982 - June 1983

Assistant Research Physician, Cancer Research Institute, University of California, San Francisco

July 1983 - June 1984

Clinical Instructor, Department of Medicine, San Francisco General Hospital and Cancer Research Institute, University of California, San Francisco

July 1983 - June 2003

Assistant Director, AIDS Activities, San Francisco General Hospital

July 1984 - June 1988

Assistant Clinical Professor, Department of Medicine, University of California, San Francisco

July 1985 - Sept 2006

Chairman, Community Consortium of Bay Area HIV Health Care Providers

July 1988 - June 1992

Associate Professor of Clinical Medicine, University of California, San Francisco

July 1992 - present

Professor of Clinical Medicine, University of California San Francisco

July 2003 - present

Chief, Hematology-Oncology, San Francisco General Hospital

August 2006 - present

Director, Clinical Programs, Osher Center, University of California, San Francisco

HONORS & AWARDS

1986-89

American Cancer Society Career Development Award

1990

Assistant Secretary of Health's Award for Outstanding Accomplishment

2000

American Foundation for AIDS Research Award of Courage

2000

International Association of Physicians in AIDS CARE (IAPAC) Heroes in Medicine Award

2002

UCSF AIDS Research Institute Sarlo Award for Excellence in Mentoring

SELECTED PUBLICATIONS

(Selected from 111)

Abrams Dl, Lewis BJ, Beckstead JH, Casavant C, Drew WL. Persistent diffuse Iymphadenopathy in homosexual men: Endpoint or Prodrome? Ann Intern Med 1984;100:801 808.

Abrams Dl, Kiprov DD, Goedert JJ, Sarngadharan MG, Gallo RC, Volberding PA. Antibodies to human T lymphotropic virus type lll antibodies and development of acquired immunodeficiency syndrome in homosexual men presenting with immune thrombocytopenia. Ann Intern Med 1985; 104:47 50

Abrams Dl, Kuno S, Wong R, Jeffords K, Nash M, Molaghan JB, Gorter R, Ueno R. Oral Dextran sulfate(UA001 ) in the treatment of the acquired immunodeficiency syndrome (AIDS) and AlDS related complex. Ann Intern Med 1989; 110:683688.

Kaplan LD, Abrams DI, Feigal E, McGrath MS, Kahn J, Neville P, Ziegler J, Volberding PA. AIDS associated non-Hodgkin's lymphoma in San Francisco. JAMA 261:719-724, 1989.

Leong G, Feigal D, Montgomery AB, Corkery K, Wardlaw L, Adams M, Busch D, Gordon S, Jacobson M, Volberding P, Abrams Dl, and the San Francisco County Community Consortium. Aerosolized pentamidine for prophylaxis against Pneumocystis carinii pneumonia. The San Francisco Community Prophylaxis Trial. NEJM 1990; 323:769 775.

Hersh EM, Brewton G, Abrams DI, Bartlett J, Galpin J, Gill P, et al. A randomized double-blind placebo-controlled multicenter study of sodium ditiocarb (diethyldithiocarbamate) therapy in patients with ARC and AIDS. JAMA 256:1538-1544, 1991.

Abrams DI, Goldman A, Launer C, Korvick J, Neaton JD, Crane L, et al and the Terry Beirn Comrnunity Programs for Clinical Research on AIDS, (CPCRA), NIAID, NIH, Washington, DC. Results of a randomized open- label comparison trial of ddI and ddC in HIV-infected patients who are intolerant of or have failed ZDV therapy: CPCRA 002. NEJM, 330:657-62, 1994.

Burack JH, Cohen MR, Hahn JA.and Abrams DI. A pilot randomized controlled trial of Chinese herbal treatment for HIV-associated symptoms, JAIDS 12:386-93, 1996.

Saravolatz LD, Winslow D, Collins G, Hodges JS, Pettinelli C, Stein D, Markowitz N, Reves R, Loveless MO, Crane L, Thompson M, Abrams DI. A comparison of ZDV alone or in combination with didanosine or zalcitabine in HIV-infected patients with AIDS or fewer than 200 CD4-positive cells per cubic millimeter. NEJM 335:1099-1106, 1996.

Slome LR, Mitchell TF, Charlebois E, Moulton Benevedes J, Abrams DI. Physician-assisted suicide and patients with human immunodeficiency virus disease. NEJM 336:417-421, 1997.

Abrams, DI. Medical marijuana: Tribulations and trials. Journal of Psychoactive Drugs, 30:163-69, 1998.

Cohen MR, Mitchell TF, Bacchetti P, Child C, Crawford S, Gaeddert A and Abrams DI. Use of a Chinese herbal medicine for treatment of HIV-associated pathogen-negative diarrhea. Integrative Medicine, 2:79-84, 1999.

Abrams, DI. Potential interventions for HIV/AIDS wasting: an overview. JAIDS, 25:S74-S80, 2000.

Corless IB, Abrams D, Nicholas PK, McGibbon CA. The use of complementary and alternative therapies. AACN Clinical Issues 11:4-6, 2000.

Kosel BW, Aweeka FT, Benowitz NL, Shade SB, Hilton JF, Lizak PS, Abrams DI. The effects of cannabinoids on the pharmacokinetics of indinavir and nelfinavir. AIDS, 16:543-550, 2002.

Abrams DI, JD Bebchuk, ET Denning, RT Davey, L Fox, HC Lane, J Neaton, J Sampson, R Verheggen, D Zeh, and N Markowitz for the Terry Beirn Community Programs for Clinical Research on AIDS. A randomized open-label study of the impact of two different doses of subcutaneous recombinant IL-2 on viral burden in patients with HIV-1 infection and CD4+ counts > 300/mm3: CPCRA 059. JAIDS, 29:221-231, 2002.

Bredt BM, Higuera-Alhino D, Shade SB, Herbert S, McCune JM, Abrams, DI. Short-term effects of cannabinoids on immune phenotype and function in HIV-1-infected patients. Journal of Clinical Pharmacology, 42:82S-89S, 2002.

Abrams DI, Hilton JF, Leiser RJ, Shade SB, Elbeik TA, Aweeka FT, Benowitz NL, Bredt BM, Kosel B, Aberg JA, Deeks SG, Mitchell TF, Mulligan K, McCune JM, Schambelan M. Short-term safety of cannabinoids in HIV infection: Results of a randomized, controlled clinical trial. Annals Intern Med, 139:258-266, 2003.

Lawrence J, Mayers DL, Hullsiek KH, Collins G, Abrams DI, Reisler RB, Crane LR, Schmetter BS, Dionne TJ, Saldanha JM, Jones MC, Baxter JD. A Multicenter Randomized Trial of Structured Treatment Interruption in Patients with Multi-Drug Resistant Human Immunodeficiency Virus-1. New Engl J Med, 349:837-846, 2003.

Carter GT, Weydt P, Kyashna-Tocha M, Abrams DI. Medical cannabis: Rational guidelines for dosing. Idrugs 2004; 7:464-470.

Behler C, Shade S, Gregory K, Abrams DI, Volberding P. Anemia and HIV in the antiretroviral era: the role of androgens. AIDS Res Hum Retroviruses 21:200-206, 2005.

Dhruva A, Cheng J, Kwong M, Luce JA, Abrams, DI. Contrasts, conflict and change: A case in cultural oncology. Supportive Oncology 4:301-304, 2006.

Astin JA, Stone J, Abrams D, Moore DH, Couey P, Buscemi R, Targ E. The efficacy of distant healing for HIV: Results of a randomized trial. Alternative Therapies in Health & Medicine12:36-41, 2006.

El-Sadr WM, Lundgren JD, Neaton JD, Gordin F, Abrams D, Arduino RC, Babiker A, Burman W, Clumeck N, Cohen CJ, Cohn D, Cooper D, Darbyshire J, Emery S, Faetkenheuer G, Gazzard B, Grund B, Hoy J, Klingman K, Losso M, Markowitz N, Neuhaus J, Phillips A, Rappaport C (Writing Group). CD4+ cell count guided antiretroviral treatment interruption and clinical outcomes among HIV-infected individuals with CD4+ cell count > 350 cells/mm3: Primary results of the Strategies for Management of Anti-Retroviral Therapy (SMART) trial. New Engl J Med 355:2283-2296, 2006.

Abrams DI, Grant R, McCune JM, Lo J, Schambelan M, Bacchetti P, Bredt B, Chang B, Couey P, Eppling L, Liegler T, Mulligan K, Shade SB, Sinclair E. Dehydroepiandrosterone (DHEA) effects on HIV-1 replication and host immunity: a randomized placebo-controlled pilot study. AIDS Research and Human Retroviruses 23:77-85, 2007.

Abrams DI, Jay C, Shade S, Vizoso H, Reda H, Press S, Kelly ME, Rowbotham M, Petersen K. Cannabis in painful HIV-associated sensory neuropathy: a randomized, placebo-controlled trial. Neurology68:515-521, 2007.

Abrams DI. An overview of integrative oncology. Clin Adv Hematol Oncol 5:45-47, 2007.

Abrams DI, Vizoso HP, Shade SB, Jay C, Kelly ME, Benowitz NL. Vaporization as a smokeless cannabis delivery system: a pilot study. Clin Pharmacol Ther April 11, 2007 [Epub ahead of print]

8/20/07

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