albertson@cc.ucsf.edu
(415) 502-8463 (voice); (415) 502-7228 (lab)
(415) 514-2678 (asst); (415) 476-8218 (fax)

Box 0808, UCSF; San Francisco, CA 94143-0808

additional websites:

Albertson Lab Website

Mount Holyoke College, MA, B.A., 1969, Biology and Chemistry
Harvard University, MA, Ph.D., 1972, Biological Chemistry
Harvard University, MA, Postdoc, 1973-1974, Molecular Cytogenetics
MRC Laboratory of Molecular Biology, UK, Postdoc, 1974-1978, Molecular Biology/Genetics

Albertson, D.G. 1984. Localization of the ribosomal genes in Caenorhabditis elegans chromosomes by in situ hybridization using biotin-labeled probes. EMBO J. 3, 1227-1234.

Albertson, D.G. 1985. Mapping muscle protein genes by in situ hybridization using biotin-labeled probes. EMBO J. 4, 2493-2498.

Albertson, D.G. Fishpool, R., Sherrington, P., Nacheva, E. and Milstein, C. 1988. Sensitive and high resolution in situ hybridization to human chromosomes using biotin labelled probes: assignment of the human thymocyte CD1 antigen genes to chromosome 1. EMBO J. 7, 2801-2805.

Birchall, P. S., Fishpool, R. M. and Albertson, D. G. 1995. Visualization of gene expression in whole organisms by FISH: cellular and subcellular localization of mRNAs for predicted genes from the C. elegans genome sequence. Nature Genet. 11, 314-320.

Pinkel, D., Segraves, R., Sudar, D., Clark, S., Poole, I., Kowbel, D., Collins, C., Kuo, W.-L., Chen, C., Zhai, Y., Dairkee, S. H., Ljung, B.-M., Gray, J. W., and Albertson, D. G. 1998. Quantitative high resolution analysis of DNA copy number variation in breast cancer using comparative genomic hybridization to DNA microarrays. Nature Genet., 20, 207-211.

Albertson, D. G., Ylstra, B., Segraves, R., Collins, C., Dairkee, S. H., Kowbel, D., Kuo, W.-L., Gray, J. W. and Pinkel, D. 2000. Quantitative Mapping of amplicon structure by array CGH identifies CYP24 as a candidate oncogene. Nature Genet. 25, 144-146.

Cheung et al. 2001. Integration of cytogenetic landmarks into the draft sequence of the human genome. Nature, 409, 953-958.

Snijders, A. M., Nowak, N., Segraves, R., Blackwood, S., Brown, N., Conroy, J., Hamilton, G., Hindle, A. K., Huey, B., Kimura, K., Law, S., Myambo, K., Palmer, J., Ylstra, B., Yue, J. P., Gray, J. W., Jain, A. N., Pinkel, D. and Albertson, D. G. 2001. Assembly of microarrays for genome-wide measurement of DNA copy number by CGH. Nature Genet. 29, 263-264.

Jain, A. N., Tokuyasu, T., Snijders, A. M., Segraves, R., Albertson, D. G. and Pinkel, D. 2001. Fully automatic quantification of microarray image data. Genome Res. 12, 325-332.

Zardo, G., Tiirikainen, M. I., Hong, C., Misra, A., Feuerstein, B. G., Volik, S., Collins C. C., Lamborn, K. R., Bollen, A., Pinkel, D., Albertson, D. G. and Costello, J. F. 2002. Integrated genomic and epigenomic analyses pinpoint biallelic gene inactivation in tumors. Nat. Genet. 32, 453-458.

Snijders, A. M., Fridlyand, J., Mans, D. A., Segraves, R., Jain, A. N., Pinkel, D. and Albertson, D. G. 2003. Shaping tumor and drug resistant genomes by instability and selection. Oncogene 20, 4370-4379.

Albertson, D. G., Collins, C., McCormick, F. and Gray, J. W. 2003. Chromosome aberrations in solid tumors. Nature Genet. 34, 369-376.

Ishkanian, A. S., Malloff, C. A., Watson, S. K., deLeeuw, R. J., Chi, B., Coe, B. P., Snijders, A., Albertson, D. G., Pinkel, D. Marra, M. A., Ling, V., MacAulay, C. and Lam, W. L. 2004. A tiling resolution DNA microarray with complete coverage of the human genome. Nature Genet. 36, 299-303.

Fridlyand, J., Snijders, A. M., Pinkel, D., Albertson, D. G. and Jain, A. N. 2004. Hidden Markov Models Approach to the Analysis of Array CGH Data. J. Mulitvariate Anal. 90, 132-153.

Snijders, A. N., Nowak, N. J., Huey, B., Fridlyand, J., Law, S., Conroy, J., Tokuyasu, T., Demir, K., Chiu, R., Mao, J.-H., Jain, A. N., Jones, S. J. M., Balmain, A., Pinkel, D. and Albertson, D.G. 2005. Mapping segmental and sequence variations among laboratory mice using BAC array CGH. Genome Res., 15, 302-311.

Snijders, A. M., Schmidt, B. L., Fridlyand, J., Dekker, N., Pinkel, D., Jordan, R. C. K. and Albertson, D. G. 2005. Rare amplicons implicate frequent deregulation of cell fate specification pathways in oral squamous cell carcinoma. Oncogene 24, 4232-4242.

Ching, T.-T., Maunakea, A. K., Peter Jun, Hong, C., Zardo, G., Pinkel, D. Albertson, D. G., Fridlyand, J., Mao, J.-H., Shchors, K., Weiss, W. A., and Costello, J. F. 2005. Epigenome analyses using BAC microarrays identify evolutionary conservation of tissue-specific methylation of SHANK3. Nature Genet. 37, 645- 651.

Pinkel, D. and Albertson, D. G. 2005. Array comparative genomic hybridization and its applications in cancer. Nature Genet. 37 Suppl:S11-7.

Albertson, D. G., Snijders, A. M., Fridlyand, J., Jordan, R., Pinkel, D., Schmidt, B. L. 2006. Genomic analysis of tumors by array comparative genomic hybridization: more is better. Cancer Res. 66, 955-3956.

Hamilton, G., Brown, N., Oseroff, V., Huey, B., Segraves, R., Sudar, D., Kumler, J., Alberston, D.G. and Pinkel, D. 2006. A large field CCD system for quantitative imaging of microarrays. Nucleic Acids Res, 34, e58.

Fridlyand, J., Snijders, A. M., Ylstra, B., Li H., Olshen, A., Segraves, R., Dairkee, S., Tokuyasu, T., Ljung, B. M., Jain, A. N., McLennan, J., Ziegler, J., Chin, K., Devries, S., Feiler, H., Gray, J. W., Waldman, F., Pinkel, D., Albertson, D. G. 2006. Breast tumor copy number aberration phenotypes and genomic instability. BMC Cancer 6, 96 [Epub ahead of print]

Albertson, D. G. 2006. Gene amplification in cancer. Trends Genet., 22, 447-455.

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