Arturo Alvarez-Buylla, PhD

Physics, 1977-1978, Queens University, Kingston, Canada
UNAM, Mexico City, Licenciado, 1983, Bio-Medicine
Rockefeller University, Ph.D., 1988, Neurobiology
Rockefeller University, Postdoc, 1988-1989, Neurobiology

• 1983-1988
  Ph.D., Rockefeller University, New York
• 1988-1989
  Postdoctoral Fellow, Rockefeller University
• 1989-1992
  Assistant Professor, Rockefeller University
• 1992-1994
  Assistant Professor/Head of Laboratory, Rockefeller University
• 1994-2000
  Associate Professor/Head of Laboratory, Rockefeller University
• 2000-2001
  Professor, Neurological Surgery, University of California, San Francisco
• 2001-8/2003
  Stephen Muss Professor, Neurological Surgery, University of California, San Francisco
• 9/2003-present
  Heather and Melanie Muss Endowed Chair, Neurological Surgery, University of California, San Francisco

• 1983
  Medal Gavino Barreda -- Universidad Nacional Autonoma de Mexico
• 1990
  First Award, The origin of new neurons in the adult avian brain
• 1992
  Sinsheimer Award
• 1994
  NIH-RO1 HD32116-01
• 2000
  Jacob Javits Award, 2000/NIH Grant RO1 NS28478
• 2001
  Brain Tumor Society. Are neural stem cells a source of brain tumors?
• 2003
  NIH R01 HD032116-09. Origins of new neurons and glia in the postnatal brain
• 2004
  Goldhirsh Foundation. Brain Tumor Research Grant 7/1/04 - 6/30/08.
• 2006
  Catedra Santiago Grisolía, Spain. Lecture and Award
• 2006
  "Académico Correspondiente Extranjero”. Real Academia de Ciencias Exactas, Físicas y Naturales. Spain
• 2007
  Catedra Ramón y Cajal, Sociedad Española de Neurología, Spain
• 2011
  Prince of Asturias Award for Technical and Scientific Research, Fundacíon Príncipe de Asturias, Spain. (Shared with Dr. Joseph Altman and Giacomo Rizzolatti)

• Wichterle H, Garcia-Verdugo JM, Herrera DG, and Alvarez-Buylla A. (1999) Young neurons from medial ganglionic eminence disperse in adult and embryonic brain. Nature Neuroscience 2:461-466.
• Doetsch F, Caille I, Lim DA, Garcia-Verdugo JM, and Alvarez-Buylla A. (1999) Subventricular zone astrocytes are neural stem cells in the adult mammalian brain. Cell 97:703-716.
• Wichterle H, Turnbull DH, Nery S, Fishell G, and Alvarez-Buylla A. (2001) In utero fate mapping reveals distinct migratory pathways and fates of neurons born in the mammalian basal forebrain. Development 128:3759-3771
• Merkle FT, Tramontin AD, Garcia-Verdugo JM and Alvarez-Buylla A. (2004) Radial glia give rise to adult neural stem cells in the subventricular zone. Proc Natl Acad Sci USA 101:17525-32
• Merkle FT, Mirzadeh Z, and Alvarez-Buylla A. (2007) Mosaic organization of neural stem cells in the adult brain. Science 317(5836):381-4
• Han YG, Spassky N, Romaguera-Ros M, Garcia-Verdugo JM, Aguilar A, Schneider-Maunoury S, and Alvarez-Buylla A. (2008) Hedgehog signaling and primary cilia are required for the formation of adult neural stem cells. Nat Neurosci 11(3):277-84.
• Mirzadeh Z, Merkle FT, Soriano-Navarro M, Garcia-Verdugo JM, Alvarez-Buylla A. (2008) Neural stem cells confer unique pinwheel architecture to the ventricular surface in neurogenic regions of the adult brain. Cell Stem Cell 3(3):265-78.
• Galvao R, Garcia-Verdugo JM, Alvarez-Buylla, A. (2008) Brain-Derived Neurotrophic Factor Signaling Does Not Stimulate Subventricular Zone Neurogenesis in Adult Mice and Rats. J Neurosci 28(50):13368-13383.
• Lim DA, Huang Y-C, Swigut T, Mirick AL, Garcia-Verdugo JM, Wysocka J, Ernst P & Alvarez-Buylla A. (2009) Chromatin remodeling factor Mll1 is essential for neurogenesis from postnatal stem cells. Nature 458(7237):529-33.
• Han YG, Kim HJ, Dlugosz AA, Ellison DW, Gilbertson RJ, Alvarez-Buylla A. (2009) Dual and opposing roles of primary cilia in medulloblastoma development. Nat Med 15(9):1062-5.
• Mirzadeh Z, Han YG, Soriano-Navarro M, Garcia-Verdugo JM, Alvarez-Buylla, A. (2010). Cilia organize ependymal planar polarity. J Neurosci 30(7):2600-10.
• Southwell DG, Froemke RC, Alvarez-Buylla A, Stryker MP, Gandhi SP. (2010) Cortical plasticity induced by inhibitory neuron transplantation. Science 327(5969):1145-8.
• Mirzadeh Z, Han YG, Soriano-Navarro M, Garcia-Verdugo JM, Alvarez-Buylla, A. (2010). Cilia organize ependymal planar polarity. J Neurosci 30(7):2600-10.
• Sanai N, Nguyen T, Ihrie R, Mirzadeh Z, Tsai H, Wong M, Gupta N, Berger M, Huang E, Garcia-Verdugo J, Rowitch D, and Alvarez-Buylla A. (2011) “Corridors of migratory neurons in human brain and their depletion during infancy.” Nature 478(7369):382-6.
• Ihrie RA, Shah JK, Harwell CC, Levine JH, Guinto CD, Lezameta M, Kriegstein AR, Alvarez-Buylla A. (2011) Persistent sonic hedgehog signaling in adult brain determines neural stem cell positional identity. Neuron. 71(2):250-62.