ABuylla@stemcell.ucsf.edu
(415) 514-2348 (voice)
(415) 514-2346 (fax)

Box 0520, UCSF; San Francisco, CA 94143-0520

Physics, 1977-1978, Queen's University, Kingston, Canada
UNAM, Mexico City, Licenciado, 1983, Bio-Medicine
Rockefeller University, Ph.D., 1988, Neurobiology
Rockefeller University, Postdoc, 1988-1989, Neurobiology

Alvarez-Buylla, A., Kirn, J.R. and Nottebohm, F. (1990) Birth of projection neurons in adult avian brain may be related to perceptual or motor learning. Science 249:1444-1446.

Alvarez-Buylla, A., Theelen, M. and Nottebohm, F. (1990) Proliferation "hot spots" in adult avian ventricular zone reveal radial cell division. Neuron 5:101-109.

Lois, C. and Alvarez-Buylla, A. (1993) Proliferating subventricular zone cells in the adult mammalian forebrain can differentiate into neurons and glia. Proc Natl Acad Sci USA 90:2074-2077.

Lois, C. and Alvarez-Buylla, A. (1994) Long-distance neuronal migration in the adult mammalian brain. Science 264:1145-1148

Lois, C., García-Verdugo, J.M., and Alvarez-Buylla, A. (1996) Chain migration of neuronal precursors. Science 271:978-981

Doetsch, F. and Alvarez-Buylla, A. Network of tangential pathways for neuronal migration in adult mammalian brain. Proc Natl Acad Sci USA 93: 14895-14900.

Doetsch F., García-Verdugo J.M. and Alvarez-Buylla, A. (1997) Cellular composition and three-dimensional organization of the subventricular germinal zone in the adult mammalian brain. J Neurosci 17: 5046-5061

Wichterle H., García-Verdugo J.M., Alvarez-Buylla, A. (1997) Direct evidence for homotypic, glia-independent neuronal migration. Neuron 18:779-791

Lim, D.A., Fishell, G.J. and Alvarez-Buylla, A. (1997) Postnatal mouse subventricular zone neuronal precursors can migrate and differentiate within multiple levels of the developing neuraxis. Proc Natl.Acad Sci USA 94: 14832-14836

Alvarez-Buylla, A., García-Verdugo, J.M., Mateo, A.S., Merchant-Larios, H. (1998) Primary neural precursors and intermitotic nuclear migration in the ventricular zone of adult canaries. J Neurosci 18: 1020-1037

Rasika, S., Alvarez-Buylla, A. and Nottebohm, F. (1999) BDNF mediates the effects of testosterone on the survival of new neurons in the adult brain. Neuron 22: 53-62

Kirschenbaum, B., Doetsch, F., Lois, C. and Alvarez-Buylla, A. (1999) Adult subventricular zone neuronal precursors continue to proliferate and migrate in the absence of the olfactory bulb. J Neurosci 19: 2171-2180

Wichterle, H., Garcia-Verdugo, J.M., Herrera, D.G., and Alvarez-Buylla, A. (1999) Young neurons from medial ganglionic eminence disperse in adult and embryonic brain. Nature Neuroscience 2:461-466.

Lim, D.A. and Alvarez-Buylla, A. (1999) Interaction between astrocytes and adult subventricular zone precursors stimulates neurogenesis. Proc Natl Acad Sci USA; 96:7526-7531.

Doetsch, F.; Caille, I.; Lim, D.A.; Garcia-Verdugo, J.M. and Alvarez-Buylla, A. (1999) Subventricular Zone Astrocytes Are Neural Stem Cells in the Adult Mammalian Brain. Cell 97: 703-716.

Doetsch, F.; Garcia-Verdugo, J.M. and Alvarez-Buylla, A. (1999) Regeneration of a germinal layer in the adult mammalian brain. Proc Natl Acad Sci USA 96:11619-11624.

Conover, J.C., Doetsch, F., Garcia-Verdugo, J.M., Gale, N.W., Yancopoulos, G.D., and Alvarez-Buylla, A. (2000) Disruption of Eph/ephrin signaling affects migration and proliferation in the adult subventricular zone. Nature Neurosci 3:1091-1097

Lim, D.A., Tramontin, A.D., Trevejo, J.M., Herrera, D.G., Garcia-Verdugo, J.M., and Alvarez-Buylla, A. (2000) Noggin antagonizes BMP signaling to create a niche for adult neurogenesis. Neuron 28: 713-726

Alvarez-Buylla, A., Garcia-Verdugo, J. M., Tramontin, A.D. (2001) A unified hypothesis on the lineage of neural stem cells. Nat Rev Neurosci 2: 287-294

Wichterle, H., Turnbull D.H., Nery, S., Fishell, G., and Alvarez-Buylla, A. (2001) In utero fate mapping reveals distinct migratory pathways and fates of neurons born in the mammalian basal forebrain. Development 128: 3759-3771

Seri, B., García-Verdugo, J. M., McEwen, B.S., Alvarez-Buylla, A. (2001) Astrocytes give rise to new neurons in the adult mammalian hippocampus, J Neurosci 21:7153-7160

Gritti, A., Bonfanti, L., Doetsch, F., Caille, I, Alvarez-Buylla, A., Lim, D.A., Galli, R., Garcia Verdugo, J.M., Herrera, D.G., and Vescovi, A.L. (2002) Multipotent Neural Stem Cells Reside into the Rostral Extension and Olfactory Bulb of Adult Rodents. J Neurosci 22:437-445

Alvarez-Buylla, A. and Garcia-Verdugo, J. M. (2002) Neurogenesis in adult subventricular zone. J Neurosci 22:629-634

Petreanu, L. and Alvarez-Buylla, A. (2002) Maturation and death of adult-born olfactory bulb granule neurons: role of olfaction. J Neurosci 22:6106-13

Doetsch, F., Petreanu, L., Caille, I., Garcia-Verdugo, J.M. and Alvarez-Buylla, A. (2002) EGF converts transit-amplifying neurogenic precursors in the adult brain into multipotent stem cells. Neuron 36:1021-1034

Alvarez-Buylla, A., Seri, B. and Doetsch, F. (2002) Identification of neural stem cells in the adult vertebrate brain. Brain Res Bull 57: 751-758

Tramontin, A.D., García-Verdugo, J.M., Lim, D.A., and Alvarez-Buylla, A. (2003) Postnatal development of radial glia and the ventricular zone (VZ): A continuum of the neural stem cell compartment. Cereb Cortex 6:580-7

Alvarez-Dolado, M., Pardal, R., Garcia-Verdugo, J.M., Fike, J.R., Lee, H.O., Pfeffer, K., Lois, C., Morrison, S.J. and Alvarez-Buylla, A. (2003) Fusion of bone marrow-derived cells with Purkinje neurons, cardiomyocytes and hepatocytes. Nature 425:968-73

Sanai, N., Tramontin, A.D., Barbaro, N.M., Gupta, N., Kunwar, S., Lawton, M.T., McDermott, M.W., Parsa, A.T., Garcia-Verdugo, J.M., Berger, M.S. and Alvarez-Buylla, A. (2004) Unique periventricular niche in adult human brain contains astrocytic stem cells but no evidence of chain migration. Nature 427:740-44

Alvarez-Buylla A. and Lim, D.A. (2004) For the Long Run: Maintaining Germinal Niches in the Adult Brain. Neuron 41:683-686

Merkle FT, Tramontin AD, Garcia-Verdugo JM and Alvarez-Buylla A. (2004) Radial glia give rise to adult neural stem cells in the subventricular zone. Proc Natl Acad Sci USA 101: 17525-32

Spassky, N., Merkle, F.T., Flamees, N., Tramontin, A., Garcia-Verdugo, J.M. and Alvarez-Buylla, A. (2005) Adult Ependymal Cells Are Postmitotic and Are Derived from Radial Glial Cells during Embyogenesis. J Neurosci. 25(1): 10-18.

Sawamoto, K., Wichterle, H., Gonzalez-Perez, O., Cholfin, J., Yamada, M., Spassky, N., Murcia, N., Garcia-Verdugo, J.M., Marin, O., Rubenstein, J., Tessier-Lavigne, M., Okano, H. and Alvarez-Buylla, A. (2006) New Neurons Follow the Flow of Cerebrospinal Fluid in the Adult Brain. Science 311(5761):629-32

Jackson, E.L., Garcia-Verdugo, J.M., Gil-Perotin, S., Roy, M., Quinones-Hinojosa, A., Vandenberg, S. and Alvarez-Buylla A. (2006) PDGFRalpha-Positive B Cells Are Neural Stem Cells in the Adult SVZ that Form Glioma-like Growths in Response to Increased PDGF Signaling. Neuron 51(2):187-99.

Menn, B., Garcia-Verdugo, J.M., Yaschine, C., Gonzalez-Perez, O., Rowitch, D. and Alvarez-Buylla, A. (2006) Origin of Oligodendrocytes in the Subventricular Zone of the Adult Brain. J Neurosci 26(30):7907-18

12/8/06