A. James Barkovich, MD

Univ. of CA, Davis, BS, 1974, Chemistry
Univ. of CA, Berkeley, MS, 1977, Chemistry Passed Oral Examination for Ph.D., was advanced to candidacy for Ph.D., but did not complete dissertation
Geo. Washington Univ., Washington, D.C., MD, 1980, Medicine
Letterman AMC, San Francisco, CA, Intern, 1980-1981, Radiology
Letterman, AMC, San Francisco, CA, Resident, 1981-1984, Radiology
Walter Reed AMC, Washington, D.C., Fellowship, 1984-1986, Neuroradiology

• 1971-1972
  Chemistry Department, Research Assistant, Univ. of CA, Davis
• 1972
  Chemistry Dept. Research Assistant Univ. of CA, Berkeley Teaching Assistant
• 1974-1972
  U.S. Army, Medical Student, Intern, Radiology Resident, Neuroradiology Fellow, Neuroradiologist, Served on active duty (highest rank - Major) in U.S. Army
• 1984-1982
  Instructor in Radiology, F. Edward Hébert School of Medicine, Uniformed Services University of Health Sciences
• 1987-1982
  Assistant Clinical Professor of Radiology, Uniformed Services University of Health Sciences
• 1986-1982
  Assistant Clinical Professor of Radiology, University of California, San Francisco
• 1989-1992
  Associate Professor of Radiology, Pediatrics, Neurology and Neurological Surgery in Residence, University of California, San Francisco
• Present
  Professor of Radiology, Pediatrics, Neurology and Neurosurgery in Residence, University of California, San Francisco

• 1972
  Edward F. Kraft Scholarship Award, U.C. Davis
• 1973-1972
  President's Undergraduate Research Fellow
• 1972
  U.S. Atomic Energy Commission Summer Research Fellow,
• 1982
  Honorable Mention, Exhibit, RSNA Annual Meeting
• 1992
  Outstanding Teacher Award, Department of Neurology, UCSF
• 1992
  Editors Excellence for Outstanding Scientific Research, J Comput Assist Tomogr
• 1992
  Elected to "Best Doctors in America"
• 1992
  Elected to "Best Doctors in America, Pacific Region"
• 1992
  Nycomed Distinguished Visiting Lecturer, Armed Forces Institute of Pathology
• 1992
  Selected to Who's Who in Medicine and Health Care
• 1992
  Goldenson Technology Award, United Cerebral Palsy Research Foundation
• 1992
  Selected to Who's Who in the World, 15th Edition
• 2002
  Selected to Who's Who in Medicine and Health Care
• 2002
  Selected to Who's Who in America, 57th Edition
• 2002 and 2002
  Listed in "America's Top Doctors"
• 2002 and 2002
  Elected to "Best Doctors in America"

• Selected (2002-present)
• AJ Barkovich. Magnetic resonance imaging: role in the understanding of cerebral malformations. Brain Dev 2002;24:2-12
  
• K Tsao, NA Chuang, RA Filly, AJ Barkovich, RB Goldstein. Entrapped fourth ventricle. Another pitfall in the prenatal diagnosis of Dandy-Walker malformations. J Ultrasound Med 2002;21:91-92
  
• EM Simon, R Hevner, JD Pinter, NJ Clegg, M Delgado, SL Kinsman, JS Hahn, AJ Barkovich, The middle interhemispheric variant of holoprosencephaly. Am J Neuroradiol 2002;23:151-152
  
• AJ Barkovich, EM Simon, NJ Clegg, SL Kinsman, JS Hahn. Analysis of the cerebral cortex in holoprosencephaly with attention to the sylvian fissures. Am J Neuroradiol 2002;23:143-152
  
• SP Miller, J Weiss, A Barnwell, DM Ferriero, B Latal-Hajnal, A Ferrer-Rogers, N Newton, JC Partridge, DV Glidden, DB Vigneron, AJ Barkovich. Seizure associated brain injury in term newborns with perinatal asphyxia. Neurology 2002;58:542-542
  
• Hayashi N, Tsutsumi Y, Barkovich AJ. Morphologic features and associated anomalies of schizencephaly in the clinical population: detailed analysis of MR images. Neuroradiology. 2002;44:418-422
  
• Kanal E, Borgstede JP, Barkovich AJ, Bell C, Bradley WG, Felmlee JP, Froelich JW, Kaminski EM, Keeler EK, Lester JW, Scoumis EA, Zaremba LA, Zinninger. American College of Radiology White Paper on MR Safety. AJR Am J Roentgenol. 2002;178:1335-1342
  
• Albayram S, Melhem ER, Mori S, Zinreich SJ, Barkovich AJ, Kinsman SL. Holoprosencephaly in Children: Diffusion Tensor MR Imaging of White Matter Tracts of the Brainstem Initial Experience. Radiology. 2002;223:645-652
  
• SP Miller, N Newton, DM Ferriero, JC Partridge, DV Glidden, A Barnwell, NA Chuang, DB Vigneron, AJ Barkovich. Predictors of 30-month outcome following perinatal depression: role of proton MRS and socio-economic factors. Pediatr Res 2002;52:71-72
  
• JM De La Cruz, RN Bamford, RD Burdine, E Roessler, AJ Barkovich, D Donnai, AF Schier, M Muenke. A loss-of-function mutation in the CFC domain of TDGF-1 is associated with human forebrain defects. Hum Genet 2002;110:422-422
  
• H Suzuki, J Takanashi, K Sugita, AJ Barkovich, Y Kohno. Retrocerebellar arachnoid cysts in siblings with mental retardation and undescended testes. Brain Dev 2002;24:310-312
  
• CL Dumoulin, KWRohling, JE Piel, CJ Rossi, RO Giaquinto, RD Watkins, DB Vigneron, AJ Barkovich, N Newton. Magnetic resonance imaging compatible neonate incubator. Magn Res Engineering 2002;15:117-122
  
• S Patel, AJ Barkovich. Analysis and classification of cerebellar malformations. Am J Neuroradiol 2002;23:1074-1082
  
• Hayashi N, Tsutsumi Y, Barkovich AJ. Polymicrogyria without porencephaly/schizencephaly. MRI analysis of the spectrum and the prevalence of macroscopic findings. Neuroradiology 2002;44(8):647-652
  
• YW Wu, SP Miller, K Chin, AE Collins, SC Lomeli, NA Chuang, AJ Barkovich, DM Ferriero. Multiple risk factors in neonatal sinovenous thrombosis. Neurology 2002;59:438-442
  
• LL Plawner, MR Delgado, V S Miller, EB Levey, SL Kinsman, AJ Barkovich, EM Simon, NJ Clegg, VT Sweet, EE Stashinko. JS Hahn. Neuroanatomy of holoprosencephaly as predictor of function: Beyond the face predicting the brain. Neurology 2002;59:1058-1062
  
• SP Miller, DB Vigneron, RG Henry, MA Bohland, C Ceppi-Cozzio, C Hoffman, N Newton, JC Partridge, DM Ferriero, AJ Barkovich. Serial quantitative diffusion tensor MRI of the premature brain: Development in newborns with and without injury. J Magn Reson Imaging. 2002;16:621-632.
• A Munoz, AJ Barkovich, F Mateos, R Simon. Symptomatic epidural lipomatosis of the spinal cord in a child: MR demonstration of spinal cord injury. Pediatr Radiol. 2002;32:865-868.
• AJ Barkovich, EM Simon, OA Glenn, NJ Clegg, SL Kinsman, M Delgado, JS Hahn. MRI shows abnormal white matter maturation in classical holoprosencephaly. Neurology 2002;59:1968-1972
  
• AJ Lewis, EM Simon, AJ Barkovich, NJ Clegg, MH DelgadoE Levey, JS Hahn. Middle interhemispheric variant of holoprosencephaly: A distinct cliniconeuroradiolgic subtype. Neurology 2002;59:1860-1862
  
• J Takanashi, AJ Barkovich, N Clegg, M Delgado, Middle interhemispheric variant of holoprosencephaly associated with polymicrogyria. Am J Neuroradiol 2003;24:394-392
  
• J Takanashi, AJ Barkovich, SF Cheng, D Kostiner, JC. Baker, S Packman. Brain MR imaging in acute hyperammonemic encephalopathy due to late-onset ornithine transcarbamylase deficiency. Am J Neuroradiol 2003;24:390-392
  
• BS Chang, X Piao, A Bodell, L Basel-Vanagaite, R Straussberg, WB. Dobyns, B Qasrawi, RM. Winter, A Innes, T Voit, PE Grant, AJ Barkovich, and CA Walsh. Bilateral frontoparietal polymicrogyria: clinical and radiological features in ten families with linkage to chromosome 16. Ann Neurol 2003;53:596-602
  
• J Takanashi, AJ Barkovich. The changing MR imaging appearance of polymicrogyria: a consequence of myelination Am J Neuroradiol 2003;24:788-792
  
• J Takanashi, AJ Barkovich, WP Dillon, EH Sherr, KA Hart, S Packman. High T1 Signal in the Pulvinar: Key Imaging Feature for Diagnosis of Fabry Disease. Am J Neuroradiol 2003;24:916-922
  
• J Takanashi, AJ Barkovich, SF Cheng, K Weisiger, C Ohnstad-Zlatunich, C Mudge, P Rosenthal, N Tuchman, S Packman. Brain MR imaging in neonatal hyperammonemic encephalopathy resulting from proximal urea cycle disorders . Am J Neuroradiol 2003;24:1184-1182
  
• YW Wu, SEG Hamrick, SP Miller, MF Haward, MC Lai, PW Callen, AJ Barkovich, DM Ferriero. Intraventricular hemorrhage in term infants caused by sinovenous thrombosis. Ann Neurol 2003;54:123-122
  
• SA Kaufman, SP Miller, DM Ferriero, DH Glidden, AJ Barkovich, JC Partridge. Encephalopathy as a predictor of MRI abnormalities in asphyxiated newborns. Pediatr Neurol 2003;28:342-342
  
• AJ Barkovich, N Girard. Fetal brain infections. Childs Nerv Syst 2003;19:501-7.
• A Weinstein, AJ Barkovich, RG Goldstein, RA Filly. In utero disappearance of the corpus callosum secondary to extensive brain injury. J Ultrasound Med 2003; Aug;22(8):837-42
  
• SP Miller, CC Cozzio, RB Goldstein, DM Ferriero, JC Partridge, DB Vigneron, AJ Barkovich. Comparing the diagnosis of white matter injury in premature newborns with serial magnetic resonance imaging and transfontanel ultrasonography. Am J Neuroradiol 2003; 24:1661-1662
  
• J Takanashi, AJ Barkovich, DM Ferriero, H Suzuki, Y Kohno. Widening spectrum of congenital hemiplegia: periventricular venous infarction in term neonates. Neurology 2003; Aug 26;61(4):531-3.
• J Takanashi, H Suzuki, AJ Barkovich, K Sugita, N Saeki, E Kobayashi, K Fujii, Y Kohno. Medullary Streaks: Dilated Medullary Vessels in Chronic Ischemia in Children. Neurology 2003; Aug 26;61(4):583-4.
• JS. Hahn, MR. Delgado, NJ. Clegg, SP. Sparagana, KL. Gerace, AJ Barkovich, DM Olson. Electroencephalography in holoprosencephaly: findings in patients without epilepsy. Clinical Neurophysiology 2003;114:1908-1912
  
• OA Glenn, JI Berman, PC Chang, R Henry, DB. Vigneron, AJ Barkovich. DTI-based 3D tractography detects differences in the pyramidal tracts of infants and children with congenital hemiparesis. J Magn Reson Imag 2003;18:641-642
  
• SEG Hamrick, SP Miller, NR Newton, JT Parer, DM Ferriero, AJ Barkovich, JC Partridge. Nucleated Red Blood Cell Counts at Birth Are Not Associated with Brain Injury or Neurodevelopmental Outcome. Pediatr Neurol 2003;29:278-282
  
• P Govaert, M Lequin, R Swarte, S Robben, R De Coo, N Weisglas, M Sinaasappel, AJ Barkovich. Changes in globus pallidus with (pre)term kernicterus. Pediatrics;2003;112:1256-1262
  
• FV Coakley, OA Glenn, A Qayyum, AJ Barkovich, R Goldstein, RA Filly. Fetal MRI: A developing technique for the developing patient. American Journal of Roentgenology 2004; 182: 243-252.
• SP Miller, H Clark, A Barnwell, B Latal, D Glidden, AJ Barkovich, DM Ferriero, and JC Partridge. Clinical Signs Predict 30-Month Neurodevelopmental Outcome Following Neonatal Encephalopathy. Am J Obstetr Gynecol 2004;190:93-92
  
• JG Gleeson, LC Keeler, MA Parisi, SE Marsh, PF Chance, IA Glass, JM Graham Jr, BL Maria, AJ Barkovich, WB Dobyns. Molar tooth sign of the midbrain-hindbrain junction: occurrence in multiple distinct syndromes. Am J Med Genet 2004;125A:125-132
  
• X Piao, RS Hill, A Bodell, BS Chang, L Basel-Vanagaite, R Straussberg, WB Dobyns, B Qasrawi, RM Winter, AM Innes, T Voit, ME Ross, JL Michaud, J-C Déscarie, AJ Barkovich, and CA. Walsh. G Protein-Coupled Receptor Patterning of the Human Frontal Cortex. Science 2004;303:2033-2032
  
• SP Miller, PS McQuillen, DB Vigneron, DV Glidden, AJ Barkovich, DM Ferriero, SEG Hamrick, A Azakie, T Karl. Preoperative brain injury in newborns with transposition of the great arteries. Ann Thoracic Surg 2004;77:1698-1702
  
• Maas LC, Mukherjee P, Carballido-Gamio J, Veeraraghavan S, Partridge SC, Henry RG, Barkovich AJ, Vigneron DB. Early laminar organization of the human cerebrum demonstrated with diffusion tensor imaging in extremely premature infants. NeuroImage 2004; 22:1134-1142
  
• Partridge SC, Mukherjee P, Henry RG, Miller SP, Berman JI, Jin H, Lu Y, Glenn OA, Ferriero DM, Barkovich AJ, Vigneron DB. Diffusion Tensor Imaging: Serial Quantitation of White Matter Tract Maturity in Premature Newborns. NeuroImage 2004; 22:1302-1312
  
• J Takanashi, AJ Barkovich, K Yamaguchi, Y Kohno. Influenza Associated Encephalitis/Encephalopathy with a Reversible Lesion in the Splenium of the Corpus Callosum Am J Neuroradiol 2004;25:798-802
  
• D Prayer, N Grois, H Prosch, H Gadner, AJ Barkovich. MR imaging presentation of intracranial disease associated with Langerhans cell histiocytosis. Am J Neuroradiol 2004;25:880-892
  
• V Ramaswamy, SP Miller, AJ Barkovich, JC Partridge, DM Ferriero. Perinatal stroke in term infants with neonatal encephalopathy. Neurology 2004;62:2088-2092
  
• BS Chang, X Piao, C Giannini, GD Cascino, I Scheffer, G Woods, M Topcu, K Tezcan, A Bodell, PE Grant, AJ Barkovich, CA Walsh, Bilateral generalized polymicrogyria (BGP): a distinct syndrome of cortical malformation. Neurology 2004;62:1722-1722
  
• VL Sheen, L Basel-Vanagaite, JR Goodman, IE Scheffer, A Bodell, VS Ganesh, R Ravenscroft, RS Hill, TJ Cherry, YY Shugart, AJ Barkovich, R Straussberg, CA Walsh. Etiological heterogeneity of familial periventricular heterotopia and hydrocephalus. Brain Dev. 2004;26:326-332
  
• SE Marsh, P Grattan-Smith, J Pereira, AJ Barkovich, JG Gleeson Neuroepithelial Cysts in a Patient with Joubert Syndrome plus Renal Cysts. J Child Neurol 2004;19:227-232
  
• D Xu, RG Henry, P Mukherjee, L Carvajal, SP Miller, AJ Barkovich, DB Vigneron. Single-shot fast spin-echo diffusion tensor imaging of the brain and spine with head and phased array coils at 1.5T and 3.0T. Magn Reson Imag 2004;22:751-752
  
• GM Enns, AJ Barkovich, ABP Van Kuilenburg, M Manning, T Sanger, DR Witt, AH Van Gennip. Head imaging abnormalities in dihydropyrimidine dehydrogenase deficiency. J Inher Metab Dis 2004;27:513-522
  
• Textbooks
• AJ Barkovich. Pediatric Neuroimaging. Raven Press, New York, 1992
  
• AJ Barkovich, CL Truwit. Practical MRI Atlas of Neonatal Brain Development. Raven Press, New York, 1990.
• J Kucharczyk, ME Moseley, AJ Barkovich, eds. Magnetic Resonance Neuroimaging. CRC, New York, 1992
  
• AJ Barkovich. Pediatric Neuroimaging, 2nd Edition. Raven Press, New York, 1992
  
• NJ Fischbein, WP Dillon, AJ Barkovich. Teaching Atlas of Brain Imaging. Thieme, New York, 2002
  
• AJ Barkovich. Pediatric Neuroimaging, 3rd Edition. Lippencott, Williams&Wilkins, Philadelphia, 2000 (Published in English, Spanish, and Portuguese)