nbenowitz@medsfgh.ucsf.edu
(415) 206-8324 (voice)
(415) 206-4956 (fax)

Box 1220, UCSF; San Francisco, CA 94143-1220

Rennselaer Polytechnic Institute, Troy, NY
University of Rochester School of Medicine, Rochester, NY, MD, 1969, Medicine
Bronx Municipal Hospital Center, Bronx, New York, Intern and Resident, Internal Medicine, 1969-1971
Fellow in Clinical Pharmacology, Department of Medicine, University of California San Francisco, 1971-1973

Al Koudsi N, Mwenifumbo JC, Sellers EM, Benowitz NL, Swan GE, Tyndale RF. Characterization of the novel CYP2A6*21 allele using in vivo nicotine kinetics. Eur J Clin Pharmacol 2006;62:481-484.

Al Koudsi N, Mwenifumbo JC, Sellers EM, Benowitz NL, Swan GE, Tyndale RF. Characterization of the novel CYP2A6*21 allele using in vivo nicotine kinetics. Eur J Clin Pharmacol 2006.

Benowitz NL, Lessov-Schlaggar CN, Swan GE, Jacob P, 3rd. Female sex and oral contraceptive use accelerate nicotine metabolism. Clin Pharmacol Ther 2006;79:480-488.

Block G, Dietrich M, Norkus Eet al. Intraindividual Variability of Plasma Antioxidants, Markers of Oxidative Stress, C-Reactive Protein, Cotinine, and Other Biomarkers. Epidemiology 2006.

Eisner MD, Balmes JR, Yelin EHet al. Directly measured secondhand smoke exposure and COPD health outcomes. BMC Pulm Med 2006;6:12.

Grosso LM, Triche EW, Belanger K, Benowitz NL, Holford TR, Bracken MB. Caffeine metabolites in umbilical cord blood, cytochrome P-450 1A2 activity, and intrauterine growth restriction. Am J Epidemiol 2006;163:1035-1041.

Hatsukami DK, Benowitz NL, Rennard SI, Oncken C, Hecht SS. Biomarkers to assess the utility of potential reduced exposure tobacco products. Nicotine Tob Res 2006;8:169-191.

Le Houezec J, Benowitz NL. Smoking habits, nicotine use, and congenital malformations. Obstet Gynecol 2006;107:1166; author reply 1168.

Lerman C, Tyndale R, Patterson Fet al. Nicotine metabolite ratio predicts efficacy of transdermal nicotine for smoking cessation. Clin Pharmacol Ther 2006;79:600-608.

Malaiyandi V, Lerman C, Benowitz NL, Jepson C, Patterson F, Tyndale RF. Impact of CYP2A6 genotype on pretreatment smoking behaviour and nicotine levels from and usage of nicotine replacement therapy. Mol Psychiatry 2006;11:400-409.

Swan GE, Hops H, Wilhelmsen KCet al. A genome-wide screen for nicotine dependence susceptibility loci. Am J Med Genet B Neuropsychiatr Genet 2006;141:354-360.

Wu X, Spitz MR, Amos CIet al. Mutagen sensitivity has high heritability: evidence from a twin study. Cancer Res 2006;66:5993-5996.

Benowitz NL, Jacob P 3rd, Bernert JT, Wilson M, Wang L, Allen F, Dempsey D. Carcinogen exposure during short-term switching from regular to "light" cigarettes. Cancer Epidemiol Biomarkers Prev. 2005;14(6):1376-83.

Swan GE, Benowitz NL, Lessov CN, Jacob P 3rd, Tyndale RF, Wilhelmsen K. Nicotine metabolism: the impact of CYP2A6 on estimates of additive genetic influence. Pharmacogenet Genomics. 15(2):115-25, 2005.

Hukkanen J, Jacob P, 3rd, Benowitz NL. Metabolism and disposition kinetics of nicotine. Pharmacol Rev. 57(1):79-115, 2005.

Gray N, Henningfield JE, Benowitz NL, Connolly GN, Dresler C, Fagerstrom K, Jarvis MJ, Boyle P. Toward a comprehensive long term nicotine policy. Tob Control. 14(3):161-165, 2005.

Swan GE, Benowitz NL, Jacob P 3rd, Lessov CN, Tyndale RF, Wilhelmsen K, Krasnow RE, McElroy MR, Moore SE, Wambach M. Pharmacogenetics of nicotine metabolism in twins: methods and procedures. Twin Res. 7(5):435-48, 2004.

Benowitz NL, Herrera B, Jacob P 3rd. Mentholated cigarette smoking inhibits nicotine metabolism. J Pharmacol Exp Ther., 310(3):1208-15, Sep 2004.

Jacob P 3rd, Haller CA, Duan M, Yu L, Peng M, Benowitz NL. Determination of ephedra alkaloid and caffeine concentrations in dietary supplements and biological fluids. J Anal Toxicol., 28(3):152-9, 2004.

Haas JS, Kaplan CP, Barenboim D, Jacob P 3rd, Benowitz NL. Bupropion in breast milk: an exposure assessment for potential treatment to prevent post-partum tobacco use. Tob Control., 13(1):52-6, 2004.

Sivarajan-Froelicher ES, NH Miller, DJ Christopherson, K Martin, KM Parker, M Amonetti, Z Lin, M Sohn, N Benowitz, CB Taylor, and P Bacchetti. High rates of sustained smoking cessation in women hospitalized with cardiovascular disease; the WomenÕs Initiative for Nonsmoking (WINS). Circulation, 109:587-593, 2004

Benowitz NL and D Dempsey. Pharmacotherapy for smoking cessation during pregnancy. Nicotine Tob. Res., 6(Suppl 2):S189-202, 2004.

Benowitz NL. Cigarette smoking and cardiovascular disease: Pathophysiology and implications for treatment. Progr. Cardiovasc, Dis., 46:91-111, 2003.

Benowitz NL, OF Pomerleau, CS Pomerleau, and P Jacob, III. Nicotine metabolite ratio as a predictor of cigarette consumption. Nicotine Tob Res, 5:621-624, 2003.

Dietrich M, G Block, NL Benowitz, JD Morrow, M Hudes, P Jacob, III, EP Norkus, and L Packer. Vitamin C supplementation decreases oxidative stress biomarker F2-isoprostane in plasma of nonsmokers exposed to environmental tobacco smoke. Nutrition and Cancer, 45:176-184, 2003.

Benowitz NL, Peng M, Jacob P III. Effects of cigarette smoking and carbon monoxide on chlorzoxazone and caffeine metabolism. Clin Pharmacol Ther, 74:468-474, 2003.

Benowitz NL. Basic cardiovascular research and its implications for the medicinal use of nicotine. J Am Coll Cardiol 41(3): 497-8, 2003.

Henningfield JE, Benowitz NL, Ahijevych K, Garrett BE, Connolly GN, Wayne GF. Does menthol enhance the addictiveness of cigarettes? An agenda for research. Nicotine Tob Res 5(1): 9-11, 2003.

Jaakkola MS, Ma J, Yang G, Chin MF, Benowitz NL, Ceraso M, Samet JM. Determinants of salivary cotinine concentrations in Chinese male smokers. Prev Med 36(3): 282-90, 2003.

Patterson F, Benowitz NL, Shields P, Kaufmann V, Jepson C, Wileyto P, Kucharski S, Lerman C. Individual differences in nicotine intake per cigarette. Cancer Epidemiol Biomarkers Prev 12(5): 468-71, 2003.

Winston L, Benowitz N. Once-daily dosing of aminoglycosides: how much monitoring is truly required? Am J Med 114(3): 239-40, 2003.

12/12/06