Kathleen M. Plant Distinguished Professor
, UCSF
Chair, Neurological Surgery; Director, Brain Tumor Research Center, UCSF
Leader, Neurologic Oncology Program, UCSF Helen Diller Family Comprehensive Cancer Center
| CONTACT | |
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bergerm@neurosurg.ucsf.edu Box 0112, UCSF; San Francisco, CA 94143-0112 |
additional websites: |
| EDUCATION | |
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Harvard University, Cambridge, MA, A.B., 1975, Social Psychology
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| PROFESSIONAL EXPERIENCE | |
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1980 - 1985 |
Residency, Dept. of Neurological Surgery, University of California, San Francisco, CA (UCSF) |
1986 - 1990 |
Asst. Professor, Dept. of Neurological Surgery, University of Washington, Seattle, WA |
1990 - 1996 |
Assoc. Professor, Dept. of Neurological Surgery, University of Washington, Seattle, WA |
1995 - 1997 |
American Cancer Society Prof. of Clinical Oncology, University of Washington, Seattle, WA |
1996 - 1997 |
Professor, Dept. of Neurological Surgery, University of Washington, Seattle, WA |
1997 - present |
Professor and Chair, Dept. of Neurological Surgery, UCSF, San Francisco, CA |
1997 - present |
Director, Brain Tumor Research Center, Dept. of Neurological Surgery, UCSF |
| HONORS & AWARDS | |
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1997-present |
Joint Section on Tumors Advisory Council, American Association of Neurological Surgeons & Congress of Neurological Surgeons |
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1997-1999 |
Vice-President, Congress of Neurological Surgeons |
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2002 - present |
America's Top Doctors, peer-nominated referral index from The Best In American Medicine: a Castle Connolly Guide |
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2006 |
Tumor Section, 2006 Ronald L. Bittner Lecturer / 2006 Farber Award Winner |
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2007 |
Board of Directors of the American Association of Neurological Surgeons |
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2007 |
Member of the American Board of Neurological Surgeons |
| SELECTED PUBLICATIONS | |
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Prados MD, McDermott M, Chang SM, Wilson CB, Fick J, Culver K, Van Gilder J, Spence A, Berger MS : Treatment of progressive or recurrent glioblastoma multiforme in adults with herpes simplex virus thymidine kinase gene vector-producer cells followed by intravenous ganciclovir administration: a phase I/II multi-institutional trial. J Neuro-Oncol 65:269-278, 2003. | |
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Schold Jr C, Kokkinakis D, Chang SM, Berger MS, Hess K, Schiff D, Robins HI, Mehta M, Fink K, Davis RL, Prados MD : O6-Benzylguanine suppression of O6-alkylguanine-DNA alkyltransferase in anaplastic gliomas. Neuro-Oncology 6: 28-32, 2004 | |
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Saito R, Bringas JR, McKnight TR, Mamot C, Drummond DC, Kirpotin DB, Park JW, Berger MS, Bankiewicz KS : Distribution of liposomes into brain and rat brain tumor models by convection-enhanced delivery monitored with magnetic resonance imaging. Cancer Res 64: 2572-2579, 2004. | |
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Pirzkall A, Li X, Oh J, Chang S, Berger MS, Larson DA, Verhey LJ, Dillon WP, Nelson SJ : 3D MR-Spectroscopy for resected high-grade gliomas prior to RT: Tumor extent according to metabolic activity in relation to MRI. Int J Radiat Oncol Biol Phys 59 (1):126-137, 2004. | |
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Kanamori M, VandenBerg S, Bergers G, Berger MS, Pieper RO : Integrin ƒÀ3 Overexpression Suppresses Tumor Growth in a Human Model of Gliomagenesis: Implications for the Role of ƒÀ3 Overexpression in Glioblastoma Multiforme. Cancer Res 64: 2751-2758, 2004 | |
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Mamot C, Nguyen JB, Pourdehnad M, Hadaczek P, Saito R, Bringas J, Drummond DC, Hong K, Kirpotin DB, McKnight T, Berger MS, Park JW, Bankiewicz KS : Extensive distribution of lipsomes in rodent brains and brain tumors following convection enhanced delivery (CED). J Neuro-Oncol 68 (1):1-9, 2004 | |
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2003 Jun 1;56(2):511-8. Erratum in: Int J Radiat Oncol Biol Phys 57(1):306l, 2003 | |
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Saito R, Bringas J, Tamas M, Pieper RO, Berger MS, Bankiewicz KS : Convection enhanced delivery of tumor necrosis factor-related apoptosis-inducing ligand with systemic administration of temozolomide prolongs survival in a U87MG intracranial xenograft. Cancer Res. 64(19):6858-62, 2004 | |
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Sanai N, Tramontin AD, Quinones-Hinojosa A, Barbaro NM, Gupta N, Kunwar S, Lawton MT, McDermott MW, Parsa AT, Verdugo JM-G, Berger MS, Alvarez-Bullya A : Unique astrocyte ribbon in adult human brain contains neural stems cells but lacks chain migration. Nature 427:1-5, 2004 | |
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Keles GE, Lundin DA, Lamborn KR, Chang EF, Berger MS : Intraoperative subcortical stimulation mapping for hemispherical perirolandic gliomas located with or adjacent to the descending pathways: evaluation of morbidity and assessment of function outcome in 294 patients. Journal of Neurosurgery 100:369-375, 2004 | |
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Keles E, Lamborn KR, Chang SM, Prados MD, Berger MS : Volume of residual disease as a predictor of outcome in adult patients with recurrent supratentorial glioblastoma multiforme undergoing chemotherapy. J Neurosurg, 100:41-46, 2004 | |
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Cha S, Tihan T, Crawford F, Fischbein N, Chang S, Parsa A, McDermott M, Bollen A, Lu Y, Prados M, Berger MS, Nelson SJ, Dillon WP : Differentiation of low-grade oligodendroglioma from low-grade astrocytoma by using quantitative blood-volume measurements derived from dynamic susceptibility contrast-enhanced MR imaging. Am J Neurorad, 2005 Feb;26(2):266-73 | |
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Chang S, Parney IF, Huang W, Asher T, Bernstein M, Lillihei K, Brem H, Berger MS, Laws E, and Glioma Outcomes Project Investigators : Patterns of care for adults with newly diagnosed malignant gliomas: data from the Glioma Outcomes Project Investigators. JAMA, 2005 Feb 2;293(5):557-64 | |
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Parney IF, Kunwar S, McDermott M, Berger M, Prados M, Cha S, Croteau D, Puri R, Chang SM : Neuroradiographic changes following convection-enhanced delivery of the conjugated toxin interleukin 13-PE38QQR for recurrent malignant glioma. J Neurosurg 2005 Feb,102(2):267-275 | |
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Smith J, Cha S, Mayo K, McDermott MW, Parsa AT, KunwarS, Chang S, Dillon WP, Prados MD, Berger MS : Serial diffusion-weighted MR imaging in glioma: distinguishing tumor recurrence from post-resection injury. J Neurosurg. 2005 Sep; 103(3):428-38. | |
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Liang Y, Diehn M, Aldape KD, Nicholas MK, Bollen AW, Lamborn KR, Berger MS, Botstein D, Brown PO, Israel MA : Gene expression profiling reveals molecularly and clinically distinct subtypes of glioblastoma multiforme. Proc Natl Acad Sci USA, 2005 April 19, 102(16):5814-5819. E-Pub April 12, 2005. | |
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Sanai N, Alvarez-Buylla A, Berger MS : Neural stem cells and the origin of gliomas. N Engl J Med. 2005 Aug 25; 353(8):811-22 | |
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Haas-Kogan DA, Prados MD, Tihan T, Eberhard DA, Jelluma N, Arvold ND, Baumber R, Lamborn KR, Kapadia A, Malec M, Berger MS, Stokoe D : Epidermal growth factor receptor, protein kinase B/Akt, and glioma response to erlotinib. J NCI, June 15, 2005 97(12):880-887 | |
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Wrensch M, Fisher JL, Schwartzbaum JA, Bondy M, Berger MS, Aldape K : The molecular epidemiology of gliomas in adults. Neurosurg Focus (electronic journal) 19(5):E5, November 2005, 1-11 | |
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Krauze MT, McKnight TR, Yamashita Y, Bringas J, Noble CO, Saito R, Geletneky K, Forsayeth J, Berger MS, Jackson P, Park JW, Bankiewicz KS : Real-time visualization and characterization of liposomal delivery into the monkey brain by magnetic resonance imaging. Cancer Res Brain Res Protoc. 2005 Dec;16(1-3):20-6. Epub 2005 Sep 21 | |
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Krauze MT, Saito R, Noble C, Tamas M, Bringas J, Park JW, Berger MS, Bankiewicz K : Reflux-free cannula for convection-enhanced high-speed delivery of therapeutic agents: technical note. J. Neurosurg 2005:103(5) November, 923-929 | |
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Noble CO, Krauze MT, Drummond DC, Yamashita Y, Saito R, Berger MS, Kirpotin DB, Bankiewicz KS, Park JW : Novel nanoliposomal CPT-11 infused by convection-enhanced delivery in intracranial tumors: pharmacology and efficacy. Cancer Res. 2006 Mar 1;66(5):2801-6. | |
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Ozturk E, Crane J, Cha S, Chang SM, Berger MS, Nelson SJ : Unaliasing lipid contamination for MR spectroscopic imaging of gliomas at 3T using sensitivity encoding (SENSE). Magn Reson Med. 2006 May 55(5) 1164-9; Epub Apr 4 | |
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Krauze M, Ryuta S, Noble C, Drummond D, Berger MS, Park J, Bankiewicz K : Convection-enhanced delivery of Ls-TPT enables an effective continuous low-dose chemotherapy against malignant glioma xenograft model. Neuro-Oncol 2006; 8(3):205-14. Epub 2006 May 24 | |
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Sanai N, Mirzadeh Z, Berger MS. : Functional outcome after language mapping for glioma resection. N Engl J Med. 2008 Jan 3;358(1):18-27. PMID: 18172171 | |
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Smith JS, Chang EF, Lamborn KR, Chang SM, Prados MD, Cha S, Tihan T, VandenBerg S, McDermott MW, Berger MS. The role of extent of resection in the long-term outcome of low-grade hemispheric gliomas J Clinical Oncol 2008 Mar 10;26(8):1338-45 | |
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2/2/09 |
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