bishop@cgl.ucsf.edu
(415) 476-3211 (voice)
(415) 476-6185 (fax)

Box 0552, UCSF; San Francisco, CA 94143-0552

additional websites:

Bishop Lab Website

Gettysburg College, Gettysburg, PA, A.B., 1957, Chemistry
Harvard University, M.D., 1962, Medicine

(Recent Publications selected from a total of 510)

Zhu, J., Woods, D., McMahon, M. and Bishop, J. M. Senescence of human fibroblasts induced by oncogenic Raf. Genes Dev. 12: 2997, 1998.

Kalman, D., Gomperts, S. N., Hardy, S., Kitamura, M. and Bishop, J. M. Ras family GTPases control astrocyte process growth. Mol. Biol. Cell, 10: 1665, 1999.

Bates, B., Rios, M., Trumpp, A., Chen, C., Fan, G., Bishop, J. M. and Jaenisch, R. Neurotrophin-3 is required for proper cerebellar development. Nature Neuroscience 2: 115, 1999.

Zhu, J., Wang, H., Bishop, J. M. and Blackburn, E. H. Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening. Proc. Natl. Acad. Sci. USA 96: 3723, 1999.

Lallemand-Breitenbach, V., Guillemin, M. C., Janin, A., Daniel, M. T., Degos, L., Kogan, S., Bishop, J. M. and de The, H. Retinoic acid and arsenic synergize to eradicate leukemic cells in a mouse model of acute promyelocytic leukemia. J. Exp. Med. 189: 1043, 1999.

Felsher, D. W. and Bishop, J. M. Transient excess of MYC activity can elicit genomic instability and tumorigenesis. Proc. Natl. Acad. Sci. USA 96: 3940, 1999.

Kalman, D., Weiner, O., Goosney, D., Sedat, J., Finlay, B.B., Abo, A., and Bishop, J. M. Enteropathogenic E. coli acts through WASP and Arp2/3 complex to form actin pedestals. Nature Cell Biology 1:389, 1999.

Trumpp, A., Depew, M.J., Rubenstein, J.L.R., Bishop, J.M., and Martin, G.R. Cre-mediated gene inactivation demonstrates that FGF8 is required for cell survival and patterning of the first branchial arch. Genes & Devel. 13:3136, 1999.

Smith-McCune, K., Kalman, D., Robbins, C., Shivakumar, S., Yuschenkoff, L. and Bishop, J. M. Intranuclear localization of human papillomavirus 16 E7 during transformation and preferential binding of E7 to the Rb family member p130. Proc. Natl. Acad. Sci. USA 96:6999, 1999.

Felsher, D. W. and Bishop, J. M. Reversible tumorigenesis by MYC in hematopoietic lineages. Mol. Cell 4:199, 1999.

Kogan, S.C., Hong, S.H., Shultz, D.B., Privalsky, M.L., and Bishop, J.M. Leukemia initiated by PMLRARalpha: the PML domain plays a critical role while retinoic acid-mediated transactivation is dispensable. Blood 95:1541, 2000.

Weiss, W.A., Godfrey, T., Francisco, C., and Bishop, J.M. Genome-wide screen for allelic imbalance in a mouse model for neuroblastoma. Cancer Research 60:2483, 2000.

Felsher, D., Zetterberg, A., Zhu, J., Tlsty, T., and Bishop, J.M. Over-expression of MYC causes p53-dependent G2 arrest of normal fibroblasts. PNAS 97:10544, 2000.

Buchholz, F., Refaeli, Y., Trumpp, A. and Bishop, J.M. Inducible chromosomal translocation of AML and ETO genes through Cre/loxP mediated recombination in the mouse. EMBO Reports. 1:1333, 2000.

Kogan, S.C., Brown, D.E., Shultz, D.B., Truong, B-T H., Lallemand-Breitenbach, V., Guillemin, M.C., Lagasse, E., Weissman, I.L., and Bishop, J.M. BCL-2 cooperates with PMLRAR_ to block neutrophil differentiation and initiate acute leukemia. J. Exper. Med. 193:531, 2001.

Buchholz, F., and Bishop, J.M. loxP directed cloning: Use of Cre recombinase as a universal restriction enzyme. Nature Biotechnology, October 2001.

Wang, R., Ferrell, L.D., Faouzi, S., Maher, J.J., and Bishop, J.M. Activation of the Met receptor by cell attachment induces and sustains hepatocellular carinomas in transgenic mice. J. Cell Biol., 153:1023, 2001.

Hahn, M., and Bishop, J.M. Expression pattern of Drosophila ret suggests a common ancestral origin between the metamorphosis precursors in endoderm and the vertebrate enteric neurons. PNAS 98: 1053, 2001.

Cheng, S. Y., and Bishop, J. M. Suppressor of Fused represses Gli-mediated transcription by recruiting the SAP18-mSin3 corepressor complex. PNAS 99: 5442, 2002.

Yang, D., Buchholz, F., Huang, Z., Goga, A., Chen, C.-Y., Brodsky, F., and Bishop, J. M. Short DNA duplexes produced by hydrolysis with Escherichia coli Rnase III mediate effective RNA interference in mammalian cells. PNAS 99: 9942, 2002.

Padua, R. A., Larghero, J., Robin, M., le Pogam, C., Schlageter, M-H, Muszlak, S., Fric, J., West, R., Rousselot, P., Phan, T. H., Liesbeth, M., Teiserenc, H., Carpentier, A. F., Kogan, S., Degos, L., Pla, M., Bishop, J. M., Stevenson, F., Charron, D., and Chomienne, D. PML-RARA-targeted DNA vaccine induces protective immunity in a mouse model of leukemia. Nature Medicine 9: 1413, 2003.

Huang, Z., Traugh, J. A., and Bishop, J. M. Negative Control of the Myc Protein by the Stress-Responsive Kinase Pak2. Molecular and Cellular Biology 24: 1582, 2004.

Yang, D., Goga, A., and Bishop,J.M. RNA Interference (RNAi) With Rnase III-Prepared siRNAs. Methods in Molecular Biology 252: 471, 2004.

Yang, D., Welm, A., and Bishop, J. M. Cell Division and Cell Survival in the Absence of Survivin. PNAS. In press 2004.

Kim, S., Chin, K., Gray, J. W., and Bishop, J. M. A Screen for Genes that Suppress the Loss of Contact Inhibition Induced by MYCN: Identification of ING4 as a Candidate Tumor Suppressor Gene in Human Cancer. PNAS. In press 2004.

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