Senior Staff Biophysicist, Life Sciences Division, Lawrence Berkeley National Laboratory
| CONTACT | |
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eablakely@lbl.gov
Lawrence Berkeley Nat'l Lab; Mailstop 70A-1118 |
additional websites: |
| EDUCATION | |
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University of San Diego, San Diego, CA, BA, 1969, Biology (Chem. Minor) |
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| PROFESSIONAL EXPERIENCE | |
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1975-1989 |
Staff Biophysicist, Lawrence Berkeley Laboratory (LBL), Univ. of California at Berkeley |
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1975-1988 |
Project Scientific Director of the Cellular and Molecular Radiobiology Program within a Program Project Grant funded by the National Cancer Institute (NCI); Deputy Scientific Director and Financial Manager of the Budgets for the NCI Program Project Grant and a DOE Grant within the Radiation Biophysics Group, Donner Laboratory, LBL |
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1988-1993 |
Principal Investigator of two DOE Grants |
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1988-1994 |
Member of the LBL-wide Technical Salary Committee |
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1988-present |
LBL Grievance Hearing Officer |
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1988-1992 |
Deputy Leader, Radiat. Biol. & DNA Repair Group, Life Sci. Div., Cell & Molec. Biol., LBL |
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1989-present |
Senior Staff Biophysicist, LBL, University of California |
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1990-1992 |
Cell and Molecular Biology Division Safety Coordinator |
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1990-1992 |
Deputy Executive Secretary, Bevalac Biomedical Program Advisory Committee |
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1991-1996 |
Project Director of a NASA-funded NSCORT (NASA Specialized Center of Research and Training for Radiation Health); Faculty Affiliate Appointment, Department of Radiological Health Sciences, Colorado State University, Fort Collins, CO |
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1993-present |
Member of the LBL-wide Radioactive Drug Research Committee |
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1994-present |
Clinical Professor of Radiation Medicine (non-tenured), Loma Linda University, School of Medicine, Loma Linda, CA |
| HONORS & AWARDS | |
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1969-72 |
U.S. A.E.C. Special Fellowship in Radiat. Sci. & Protect., Dept. of Phys. & Biophys. Univ. of Ill. |
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1974 |
Robert Emerson Graduate Teaching Award, School of Life Sciences, University of Illinois |
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1979 |
Nominated for listing in American Men and Women in Science |
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1992 |
Lawrence Berkeley Laboratory Outstanding Performance Award |
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2002 |
DOE Office of Science Outstanding Mentor Award |
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2004 |
Lawrence Berkeley Laboratory Outstanding Performance Award |
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2004 |
Lawrence Berkeley Laboratory Technology Transfer Award |
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2005 |
RD100 award from R&D (Research & Development) Magazine as a member of a team that developed one of the 100 best new technologies in the year 2005 |
| SELECTED PUBLICATIONS | |
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Blakely, E.A., F.Q.H. Ngo, S.B. Curtis, and C.A. Tobias. Heavy-ion radiobiology: Cellular studies. Adv. in Radiat. Biol. 11, 295-389, 1984. | |
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Blakely, E.A., P.Y. Chang, and L. Lommel. Cell-cycle-dependent recovery from heavy-ion damage. Radiat. Res. 104, S145-S157, 1985. | |
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Blakely, E., R. Roots, P. Chang, L. Lommel, L. Craise, E. Goodwin, and E. Yee. Cell-cycle-dependent X-ray OER: Role of endogenous glutathione. NCI Mono-Interact. of Rad.&Chemotherapy.Vol.6, 217-223, 1988. | |
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Kronenberg, A. and E.A. Blakely. Locus specificity of mutation in human lymphoblastoid cells: LET effects. In Cell Transformation and Radiation-Induced Cancer in Man (Eds. K.H. Chadwick, C. Seymour, and B. Barnhart). Adam Hilger Ltd., pp. 215-222, 1989. | |
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Castro, J.R., E.A. Blakely, and D.A. Linstadt. Particle therapy in treatment of urologic tumors. Adv. in Urologic Oncology, Vol. II, pp. 149-160, 1990. | |
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Chang, P.Y., C.A. Tobias, and E.A. Blakely. Protein synthesis modulates the biological effectiveness of the combined action of hyperthermia and high-LET radiation. Radiat. Res. 129, 272-280, 1992. | |
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Blakely, E.A. Cell inactivation by heavy-charged particles. Radiat. and Environ. Biophys. 31,181-196, 1992. | |
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Castro, J.R., P.L.Petti, I.K.Daftari, J.M.Collier, T. Renner, B. Ludewigt, W. Chu, S. Pitluck, T. Fleming, J. Alonso, and E. Blakely. Clinical gain from improved beam delivery systems. Radiat. Environ. Biophys. 31, 233-240, 1992. | |
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Blakely, E.A., I.K. Daftari, W.J. Meecham, L.C. Alonso, et al. Helium-ion-induced human cataractogenesis. Adv. Space Res., Vol. 14, No. 10, pp. (10)501-(10)505, 1994. | |
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Meecham, W.J., S.M. Kroll, D.H. Char, J.R. Castro and E.A. Blakely. Anterior segment complications after helium ion radiation therapy for uveal melanoma, I. Radiation cataract. Arch.Ophthalmol. 112,197-203,1994. | |
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Goodwin, E.H., E.A. Blakely, and C.A. Tobias. Chromosomal damage and repair in G1-phase CHO cells exposed to charged particle beams. Radiat. Res, 138, 343-351, 1994. | |
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Blakely, E. A. and R.J.M. Fry. Radiation protection in space, Radiat. Environ. Biophys. 34,129-131, 1995. | |
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Blakely, E. A., Biological Beam Characterization. In Ion Beams in Tumor Therapy (Ed. U. Linz). Chapman & Hall, New York, pp. 63-72, 1995. | |
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Daftari, I., D. Char, L.Verhey, J. Castro, P. Petti, W. Meecham, S. Kroll, E.A. Blakely. Anterior normal tissue sparing as a means of reducing complications of charged particle radiotherapy in uveal melanoma. Int. J. Radiat. Oncol., Biol., Physics 39, 989-996, 1997. | |
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Castro, J., D. Char, P. Petti, I. Daftari, J. Quivey, R.P. Singh, E.A. Blakely and T. Phillips. 15 years experience with helium ion radiotherapy for uveal melanoma. Int. J. Radiat. Oncol, Biol., Physics 39, 997-1010, 1997. | |
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Blakely, E.A., and A. Kronenberg. Heavy-ion radiobiology: New approaches to delineate mechanisms underlying enhanced biological effectiveness. Radiat. Res. 150, S126-S145, 1998. | |
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Castro, J.R., P.L. Petti, E.A.Blakely and D.E. Linstadt. Particle Radiation Therapy. In Textbook of Radiation Oncology (Eds. Leibel and Phillips), W. B. Saunders Co., Philadelphia, PA, 1998. | |
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Callahan, D.E., T.M. Forte, S.M.J. Afzal, D.F. Deen, S.B. Kahl, K.A. Bjornstad, W.F. Bauer and E.A. Blakely. Boronated protoporphyrin (BOPP): Localization in lysosomes of the human glioma cell line SF-767 with uptake modulated by lipoprotein levels. Int. J. Radiat. Oncol. Biol. Physics 45,761-771, 1999. | |
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Maletinska, L., E.A. Blakely, K.A. Bjornstad, D.F. Deen, L.J. Knoff and T.M. Forte. Human glioblastoma cell lines: Levels of low density lipoprotein receptor and low density lipoprotein receptor-related protein. Cancer Research 60, 2300-2303, 2000. | |
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Holman, H.Y., M.C. Martin, E.A. Blakely, K. Bjornstad and W.R. McKinney. Infrared spectroscopic characteristics of cell cycle and cell death probed by synchrotron-based FTIR spectromicroscopy. Biospectroscopy 57, 329-335, 2000. | |
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Chang, P.Y., K.A. Bjornstad, E. Chang, M. McNamara, M.H. Barcellos-Hoff, S.P. Lin, G. Aragon, J.R. Polansky, G.M. Lui and E.A. Blakely. Particle irradiation induces FGF-2 expression in normal human lens cells. Radiat. Res. 154,477-484, 2000. | |
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Blakely, E.A., K.A. Bjornstad, P.Y. Chang, M.P. McNamara, E. Chang, G. Aragon, S.P. Lin, G.M. Lui and J.R. Polansky. Growth and differentiation of human lens epithelial cells in vitro on matrix. Invest. Ophthalmol. & Visual Sci. 41, 3898-3907, 2000. | |
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Blakely, E.A. Biological Effects of Cosmic Radiation: Deterministic & Stochastic. Health Phys. 79,495-505, 2000. | |
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McNamara, M.P.J., K.A. Bjornstad, P.Y. Chang, W. Chou, S.J. Lockett and E.A. Blakely. Modulation of lens cell adhesion molecules by particle beams. Physica Medica, Vol. XVII, Supplement 1, pp. 247-248, 2001. | |
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Blakely, E. A. New measurements for hadrontherapy and space radiation: Biology. Physica Medica, Vol XVII, Supplement 1, pp. 50-58, 2001. | |
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Holman, H.Y., K.A. Bjornstad, M.P. McNamara, M.C. Martin, W.R. McKinney and E.A. Blakely. Synchrotron infrared spectromicroscopy as a novel bioanalytical microprobe for individual living cells: cytotoxicity considerations. J. Biomed. Optics 7(3), 417-424, 2002, & selected for Virtual J. Biol. Phys. Res. 4(3), 2002. | |
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Mainardi, E., R.J. Donahue, W.E. Wilson, and E.A. Blakely, Comparison of microdosimetric simulations using PENELOPE and PITS for a 25 keV electron microbeam in water, Radiat. Res. 162,326-331, 2004. | |
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Blakely, E.A. and P. Y. Chang, Late effects from hadron therapy, Radiotherapy & Oncology, Suppl. 2, Vol. 73, S134-S140, 2004. | |
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Chang, PY, KA Bjornstad, CJ Rosen, MP McNamara, R Mancini, LE Goldstein, LT Chylack, and EA Blakely Effects of iron ions, protons and xrays on human lens cell differentiation, Radiat. Res. 164(4): 531-539, 2005. | |
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7/11/06 |
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