Adjunct Assistant Professor, Dept. of Pediatrics (Hematology/Oncology), UCSF
| CONTACT | |
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(415) 353-2584 (appts) Box 0106, UCSF; San Francisco, CA 94143-0106 |
additional websites: |
| EDUCATION | |
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Princeton University, A.B., 1990, Molecular Biology
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| PROFESSIONAL EXPERIENCE | |
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1992-1996 |
Graduate Student, Laboratory of Christopher Denny, M.D., University of California, Los Angeles (Project: mechanism of oncogenesis by the Ewing sarcoma fusion protein EWS-FLI) |
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1998-2000 |
Resident, Department of Pediatrics, University of California, San Francisco |
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2000-2003 |
Clinical Fellow, Hematology/Oncology, University of California, San Francisco |
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2001-present |
Post-doctoral researcher, Laboratory of Kevin Shannon, M.D., University of California, San Francisco (Project: myeloid proliferation and neoplasia initiated by mutant Kras) |
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2004-2005 |
Adjunct Instructor, Department of Pediatrics, University of California, San Francisco |
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2005-present |
Adjunct Assistant Professor, Department of Pediatrics, University of California, San Francisco |
| HONORS & AWARDS | |
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1990 |
Cum Laude, Princeton University |
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1990 |
Phi Beta Kappa |
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1990 |
Medical Scientist Training Program Fellowship, University of California, Los Angeles |
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2000-2003 |
Campini Fellowship, University of California, San Francisco |
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2004 |
David G. Nathan Award, Society for Pediatric Research |
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2004 |
Melvin Grumbach Pediatric Research Award, UCSF |
| SELECTED PUBLICATIONS | |
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Lewis BC, Shah NP, Braun BS, and Denny CT. Creation of a yeast artificial chromosome fragmentation vector based on lysine-2. Genetic Analysis, Techniques and Applications 9(3):86-90, 1992. |
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Ku G, Kronenberg M, Peacock DJ, Tempst P, Banquerigo ML, Braun BS, Reeve JR Jr, and Brahn E. Prevention of experimental autoimmune arthritis with a peptide fragment of type II collagen. European Journal of Immunology 23(3):591-9, 1993. |
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May WA, Lessnick SL, Braun BS, Klemsz M, Lewis BC, Lunsford LB, Hromas R, and Denny CT. The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1. Molecular and Cellular Biology 13(12):7393-8, 1993. |
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Lessnick SL, Braun BS, Denny CT, and May WA. Multiple domains mediate transformation by the Ewing's sarcoma EWS/FLI-1 fusion gene. Oncogene 10(3):423-31, 1995. |
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Jeon IS, Davis JN, Braun BS, Sublett JE, Roussel MF, Denny CT, and Shapiro DN. A variant Ewing's sarcoma translocation (7;22) fuses the EWS gene to the ETS gene ETV1. Oncogene 10(6):1229-34, 1995. |
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Braun BS, Frieden R, Lessnick SL, May WA, and Denny CT. Identification of target genes for the Ewing's sarcoma EWS/FLI fusion protein by representational difference analysis. Molecular and Cellular Biology 15(8):4623-30, 1995. |
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Thompson AD, Braun BS, Arvand A, Stewart SD, May WA, Chen E, Korenberg J, and Denny C. EAT-2 is a novel SH2 domain containing protein that is up regulated by Ewing's sarcoma EWS/FLI fusion gene. Oncogene 13(12):2649-58, 1996. |
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May WA, Arvand A, Thompson AD, Braun BS, Wright M, and Denny CT. EWS/FLI1 induced Manic Fringe renders NIH 3T3 cells tumorigenic. Nature Genetics 17(4):495-7, 1997. |
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Braun BS, Tuveson DA, Kong N, Le DT, Kogan SC, Rozmus J, Le Beau MM, Jacks TE, and Shannon K. Somatic Activation of Oncogenic Kras in Hematopoietic Cells Initiates a Rapidly Fatal Myeloproliferative Disorder. Proc Natl Acad Sci U S A 101(2):597-602, 2004. |
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Le DT, Kong N, Zhu Y, Lauchle JO, Aiyigari A, Braun BS, Wang E, Kogan SC, Le Beau MM, Parada L, Shannon KM. Somatic inactivation of Nf1 in hematopoietic cells results in a progressive myeloproliferative disorder. Blood 103(11):4243-50, 2004. |
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Zhang IH, Zane LT, Braun BS, Maize J Jr, Zoger S, Loh ML. Congenital leukemia cutis with subsequent development of leukemia. J Am Acad Dermatol 54(2 Suppl):S22-7, 2006. |
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Braun BS, Archard J, Van Ziffle JA, Tuveson DA, Jacks TE, Shannon KM. Somatic Activation of a Conditional KrasG12D Allele Causes Ineffective Erythropoiesis In Vivo. Blood 108(6):2041-4, 2006. |
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Invited Chapters and Reviews |
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Sato Y, Shah N, Braun B, and Denny C. Manipulation of large genomic constructs using yeast artificial chromosomes. In Adolph, KW (ed.), Methods in Molecular Genetics, vol. 5, Gene and Chromosome Analysis Part C. San Diego: Academic Press, 1994. pp 159-168. |
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Braun BS, and Shannon K. The sum is greater than the FGFR1 partner. Cancer Cell 5(3):203-4, 2004. |
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Lauchle JO, Braun BS, Loh ML, Shannon K. Inherited predispositions and hyperactive Ras in myeloid leukemogenesis. Pediatr Blood Cancer 46(5):579-85, 2006. |
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11/21/06 |
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