Michael J. Campbell, PhD
Assistant Adjunct Professor, Department of Surgery, UCSF
Contact
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(415) 885-3710 (voice)
(415) 885-7617 (fax) (fax)
Box 1674, UCSF; San Francisco, CA 94143-1674
Education
University of Puget Sound, Tacoma, WA, B.S., 1978-1982, Biology
Stanford University, Stanford, CA, Ph.D., 1982-1987, Cancer Biology
Stanford University, Stanford, CA, post-doc, 1987-1989, Tumor immunology and immunotherapy
Professional Experience
-
1989-1991
Research Associate, Department of Medicine/Division of Oncology, Stanford University, School of Medicine, Stanford, CA.
- 1991-1992
Research Associate, Department of Surgery, Stanford University School of Medicine, Stanford, CA.
- 1992-1997
Research Assistant Professor, Department of Surgery, Stanford University School of Medicine, Stanford, CA.
- 1997-present
Assistant Adjunct Professor, Department of Surgery, University of California, San Francisco, CA
Honors & Awards
- 1982-1986
NIH - National Research Service Award, Graduate Fellowship
- 1987-1988
Stanford University Dean's Postdoctoral Fellowship Award
- 1988-1989
NIH - National Research Service Award, Postdoctoral Fellowship
Selected Publications
- Campbell, M., M. Bieber, R. Levy and N.N.H. Teng. 1986. Influence of avidity and idiotope recognition on the modulation of surface immunoglobulin on malignant human B cells by rat monoclonal anti-idiotype antibodies. J Immunol 136:2983.
- Lowder, J.N., T.C. Meeker, M. Campbell, C.F. Garcia, J. Gralow, R.A. Miller, R. Warnke and R. Levy. 1987. Studies on B lymphoid tumors treated with monoclonal anti-idiotype antibodies: Correlation with clinical responses. Blood 69:199.
- Campbell, M.J., W. Carroll, S. Kon, K. Thielemans, J.B. Rothbard, S. Levy and R. Levy. 1987. Idiotype vaccination against murine B cell lymphoma. Humoral and cellular responses elicited by tumor-derived immunoglobulin M and its molecular subunits. J Immunol 139:2825.
- Campbell, M.J., L. Esserman and R. Levy. 1988. Immunotherapy of established murine B cell lymphoma. Combination of idiotype immunization and cyclophosphamide. J Immunol 141:3227.
- Starnes, C.O., W.L. Carroll, M.J. Campbell, L.L. Houston, G. Apell and R. Levy. 1988. Heterogeneity of a murine B cell lymphoma. Isolation and characterization of idiotypic variants. J. Immunol 141:333.
- Basham, T.Y., E.R. Race, M.J. Campbell, T.R. Reid, R. Levy and T.C. Merigan. 1988. Synergistic antitumor activity with IFN and monoclonal anti-idiotype for murine B cell lymphoma. Mechanism of action. J Immunol 141:2855.
- Campbell, M.J., L. Esserman, N.E. Byars, A.C. Allison, and R. Levy. 1989. Development of a new therapeutic approach to B cell malignancy. The induction of immunity by the host against cell surface receptor on the tumor. Intern Rev Immunol 4:251.
- Levy, S., M.J. Campbell, and R. Levy. 1989. Functional immunoglobulin light chain genes are replaced by ongoing rearrangements of germline Vk genes to downstream Jk segments in a murine B cell line. J Exp Med 170:1.
- Kwak, L.W., M.J. Campbell, A.D. Zelenetz, and R. Levy. 1990. Combined syngeneic bone marrow transplantation and immunotherapy of a murine B cell lymphoma: active immunization with tumor-derived idiotypic immunoglobulin. Blood 76:2411.
- Campbell, M.J., L. Esserman, N.E. Byars, A.C. Allison, and R. Levy. 1990. Idiotype vaccination against murine B cell lymphoma. Humoral and cellular requirements for the full expression of anti-tumor immunity. J Immunol 145:1029.
- Kwak, L.W., M.J. Campbell and R. Levy. 1991. Idiotype vaccination post-bone marrow transplantation for B cell lymphoma: initial studies in a murine model. Cancer Detect. Prevent. 15:323.
- Bahler, D.W., M.J. Campbell, S. Hart, R. Miller, S. Levy and R. Levy. 1991. Ig VH gene expression among human follicular lymphomas. Blood. 78:1561.
- Kwak, L.W., M.J. Campbell, A.D. Zelenetz, and R. Levy. 1991. Transfer of specific immunity to B cell lymphoma with syngeneic bone marrow in mice: A strategy for using autologous marrow as an anti-tumor therapy. Blood. 78:2768.
- Campbell, M.J., A.D. Zelenetz, S. Levy, and R. Levy. 1992. Use of family specific leader region primers for PCR amplification of the human heavy chain variable region gene repertoire. Mol. Immunol. 29:193.
- Kwak, L.W., M.J. Campbell, D.K. Czerwinski, S. Hart, R.A. Miller, and R. Levy. 1992. Induction of immune responses in patients with B-cell lymphma against the surface-immunoglobulin idiotype expressed by their tumors. N.Engl. J. Med. 327:1209.
- Clayberger C., S. Luna-Fineman, J.E. Lee, A. Pillai , M. Campbell, R. Levy, and A.M. Krensky. 1992. Interleukin 3 is a growth factor for human follicular B cell lymphoma. J. Exp. Med. 175:371.
- Hsu, F.J., L. Kwak, M. Campbell, T. Liles, D. Czerwinski, S. Hart, A. Syrengelas, R. Miller, and R. Levy. 1993. Clinical trials of idiotype-specific vaccine in B-cell lymphomas. Ann. N.Y. Acad. Sci. 690:385.
- Campbell, M.J. 1993. Biology of lung cancer. In Current therapy in oncology. J.E. Niederhuber, ed. Mosby-Year Book, St Louis. P. 175.
- Drebin, J.A., S.W. Hartzell, C. Griffen, M.J. Campbell, and J.E. Niederhuber. 1995. Molecular cloning and chromosomal localization of the human homologue of a B-lymphocyte specific protein tyrosine kinase (blk). Oncogene. 10:477.
- Campbell, M.J. 1995. Lipofection reagents prepared by a simple ethanol injection technique. Biotechniques. 18:1027-1032.
- Lin, Y.H., E.J. Shin, M.J. Campbell, and J.E. Niederhuber. 1995. Transcription of the blk gene in human B lymphocytes is controlled by two promoters. J. Biol. Chem. 270:25968-25975.
- Campbell, M.J., P.J. McFall, and J.E. Niederhuber. 1995. Production and characterization of a monoclonal antibody against Schistosoma japonicum glutathione S-transferase. J. Immunol. Meth. 188:73-78.
- Campbell, M.J., A. Meier, Y.H. Lin, and J.E. Niederhuber. 1997. Oncogenic activity and aberrant hypermethylation of the human blk gene. Proc. Am. Assoc. Cancer Res. 38:178.
- Esserman, L.J., T. Lopez, R. Montes, L.N. Bald, B.M. Fendly, and M.J. Campbell. 1999. Vaccination with the extracellular domain of p185neu prevents mammary tumor development in neu transgenic mice. Cancer Immunol. Immunother. 47:337-342.
- Borden, E.C., L. Esserman, D.J. Linder, M.J. Campbell, and A.M. Fulton. 1999. Biological therapies for breast carcinoma: concepts for improvements in survival. Seminars in Oncol. 26:28-40.
- Mukherjee, S., S.G. Louie, M.J. Campbell, L.J. Esserman, and G. Shyamala. 2000. Ductal growth is impeded in mammary glands of C-neu transgenic mice. Oncogene 19:5982-5987.
- Jabrane-Ferrat, N., M. Campbell, M. Peterlin, and L. Esserman. 2000. Antigen presentation prevents tumor development in tumor challenged Her-2 transgenic mice. Breast Cancer Res Treat. 64:34.
- Campbell, M.J., J. Scott, L.J. Esserman, and H. Maecker. 2000. Analysis of type 1 and type 2 T cells in breast cancer by intracellular cytokine staining and flow cytometry. Breast Cancer Res Treat. 64:112.
- Park, J.W., D. Tripathy, M.J. Campbell, and L.J. Esserman. 2000. Biological therapy of breast cancer. BioDrugs. 14:221.
Updated: September 21, 2010