Jennifer L. Clarke, MD, MPH

California Institute of Technology (Caltech), Pasadena, CA, B.S., 1995, Chemistry, With Honor
University of California, San Francisco, M.D., 2002, Medicine
University of California, Berkeley, M.P.H., 2001, Health Policy and Mgmt
St. Mary’s Medical Center, San Francisco, 06/03, Intern, Internal Medicine
University of California, San Francisco, 06/06, Resident, Neurology
Memorial Sloan-Kettering Cancer Center, 06/08, Fellow, Neuro-oncology

• 6/95-8/97
  Combion, Inc.
• 7/02-6/03
  St. Mary’s Medical Center, San Francisco Intern Medicine
• 7/03-6/06
  University of California, San Francisco Resident Neurology
• 7/05-6/06
  University of California, San Francisco Chief Resident Neurology
• 7/06-6/08
  Memorial Sloan-Kettering Cancer Center Fellow Neuro-Oncology
• 7/07-6/08
  Memorial Sloan-Kettering Cancer Center Chief Fellow Neuro-Oncology
• 8/08-6/10
  University of California, San Francisco Assistant Clinical Professor of Neurology and Neurological Surgery (Division of Neuro-Oncology)
• 8/10 – present
  University of California, San Francisco Assistant Professor of Clinical Neurology and Neurological Surgery (Division of Neuro-Oncology)

• 1999
  Nomination for “An Outstanding Lecture” UCSF Class of 2001
• 2000
  University Fellowship, UC-Berkeley
• 2000
  Award for “An Outstanding Lecture” UCSF Class of 2002
• 2001
  UCSF Class of 1966 Scholarship
• 2003
  Intern of the Year, St. Mary’s Medical Center
• 2008
  ASCO Foundation Merit Award
• 2009
  Awarded a fellowship to the 2nd Annual Clinical Trials Methods Course in Neurology, in Vail, Colorado, August 17-23, 2009; the course is sponsored by NINDS

• Clarke, J., Johnston, S.C., Bernstein, R., Tong, D., Hemphill III, J.C. External Validation of the ICH Score. Neurocritical Care. Spring 2004;1(1):53-60.
• Chang, S.M., Nelson, S., VandenBerg, S., Cha, S., Prados, M., Butowski, N., McDermott, M., Parsa, A.T., Aghi, M., Clarke, J., Berger, M. Integration of preoperative anatomic and metabolic physiologic imaging of newly diagnosed glioma. J. Neuroonc. 2009;92:401-15.
• Clarke, J., Iwamoto, F., Sul J., Panageas, K., Lassman, A., DeAngelis, L., Hormigo, A., Nolan C., Gavrilovic, I., Karimi, S., Abrey, L. A randomized phase II trial of chemoradiotherapy followed by dose-dense versus metronomic temozolomide for newly diagnosed glioblastoma. JCO. 2009;27(23):3861-67.
• Polley, M-Y. C., Lamborn, K.R., Chang, S.M., Butowski, N., Clarke, J.L., Prados, M. Six-month progression-free survival as an alternative primary efficacy endpoint to overall survival in newly-diagnosed glioblastoma patients receiving temozolomide. Neuro-Oncology. 2010;12(3):274-82.
• Clarke, J.L., Perez, H.R., Jacks, L.M., Panageas, K.S., DeAngelis, L. M. Leptomeningeal metastases in the MRI Era. Neurology. 2010;74(18):1449-54.
• Clarke, J., Wu, N., Miller, V., Pao, W., Lassman, A. High-dose weekly erlotinib achieves therapeutic concentrations in CSF and is effective in leptomeningeal metastases from epidermal growth factor receptor mutant lung cancer.. J Neuro-Onc. 2010 Sep;99(2):283-6.
• Clark, A., Butowski, N., Chang, S., Prados, M., Clarke, J., Polley, M-Y., Sughrue, M., McDermott, M., Parsa, A., Berger, M., Aghi, M. Impact of Bevacizumab Chemotherapy on Craniotomy Wound Healing. J Neurosurgery. Epub Dec 10, 2010.
• Parvataneni R., Polley M.Y., Freeman T., Lamborn K., Prados M., Butowski N., Liu R., Clarke J., Page M., Rabbitt J., Fedoroff A., Clow E., Hsieh E., Kivett V., Deboer R., Chang S. Identifying the needs of brain tumor patients and their caregivers. J Neurooncol. Epub Feb 11, 2011.
• Clarke, J.L., Ennis, M.M., Yung, W.K.A., Chang, S.M., Wen, P.Y., Cloughesy, T.F., DeAngelis, L.M., Robins, H.I., Lieberman, F.S., Fine, H.A., Abrey, L., Gilbert, M.R., Mehta, M., Kuhn, J.G., Aldape, K.D., Lamborn, K.R., Prados, M.D.; North American Brain Tumor Consortium. Is surgery at progression a prognostic marker for improved 6-month progression-free survival or overall survival for patients with recurrent glioblastoma? Neuro-Oncology. Epub Aug 2, 2011.
• Polley, M-Y. C., Lamborn, K.R., Chang, S.M., Butowski, N., Clarke, J.L., Prados, M. The Conditional Probability of Survival in Newly-Diagnosed Glioblastoma Patients. JCO. In press (2011).
• Grommes, C., Oxnard, G.R., Kris, M.G., Miller, V.A., Pao, W., Holodny, A.I., Clarke, J.L., Lassman, A.B. “Pulsatile” High Dose Weekly Erlotinib for Central Nervous System Metastases from EGFR Mutant Non-Small Cell Lung Cancer. Neuro-Oncology. In press (2011).