Postdoctoral Fellow, McMahon Lab, UCSF Helen Diller Family Comprehensive Cancer Center
| CONTACT | |
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ddankort@cc.ucsf.edu Box 0128, UCSF; San Francisco, CA 94143-0128 |
| EDUCATION | |
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McMaster University, Hamilton, ON, Canada, B.Sc. (hons), 1990, Biology
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| PROFESSIONAL EXPERIENCE | |
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05/89-09/90 |
Undergraduate research personnel and senior year thesis, McMaster University. Dr. Philip E. Branton Chair of Biochemistry, McGill University.
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11/90-08/92 |
M.Sc. student, Department of Biology, McMaster University. Dr. WJ Muller, Professor.
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08/92-11/00 |
Ph.D. graduate program, Department of Biology, McMaster University. Dr. WJ Muller, Professor.
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09/96-04/99 |
Post-doctoral fellow, Inst. Mol. Biol. & Biotech. McMaster University. Dr. WJ Muller, Professor.
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10/99-present |
Post-doctoral fellow, UCSF Cancer Research Institute. Dr. Martin McMahon, Associate Professor.
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| HONORS & AWARDS | |
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1990 |
McMaster University Centennial Award |
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1990-1991 |
Ontario Graduate Scholarship |
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1991 |
Ontario Graduate Scholarship (declined) |
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1992 |
Natural Science and Engineering Research Council (N.S.E.R.C.), Postgraduate Scholarship (PGS 2/PGS A), 1991-1992 Ontario Graduate Scholarship (declined) |
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1994-1996 |
Natural Science and Engineering Research Council (N.S.E.R.C.), Postgraduate Scholarship (PGS B), 1992-1994 Cancer Research Society Scholarship |
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2002-2003 |
General Motors Cancer Research Scholar |
| SELECTED PUBLICATIONS | |
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Journal Articles |
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D Dankort, N Jeybala, N Jones, DJ Dumont, and WJ Muller (2001) Multiple ErbB-2/Neu phosphorylation sites mediate transformation through distinct effector proteins. JBC 276: 38921-38928. |
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D Dankort, B Maslikowski, N Warner, N Kanno, H Kim, Z Wang, MF Moran, RG Oshima, RD Cardiff and WJ Muller. (2001) Grb2 and Shc adapter proteins play distinct roles in ErbB-2/Neu-induced mammary tumorigenesis: implications for human breast cancer. Mol. Cell. Biol. 21(5): 7068-7077. |
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Khoury H, DL Dankort, S Sadekova, MA Naujokas, WJ Muller and M Park. (2001) Distinct tyrosine autophosphorylation sites mediate induction of epithelial mesenchymal like transition by an activated ErbB-2/Neu receptor. Oncogene 20(7):788-99 |
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Dankort, DL, Z Wang, V Blackmore, MF Moran and WJ Muller (1997) Distinct tyrosine autophosphorylation sites negatively and positively modulate Neu-mediated transformation Mol. Cell. Biol. 17(9): 5410-5425. |
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Siegel, PM, DL Dankort, WR Hardy and WJ Muller (1994) Novel activating mutations in the neu proto-oncogene involved in induction of mammary tumors Mol. Cell. Biol. 14(11): 7068-7077. |
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Muthuswamy, SK, PM Siegel, DL Dankort, MA Webster and WJ Muller (1994) Mammary tumors expressing the neu proto-oncogene possess elevated c-Src tyrosine kinase activity Mol. Cell. Biol. 14(1): 735-743. |
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Rowely, RB, JM Lee, H Corbell, R Charbonneau, K Jue, DL Dankort and PE Branton (1993) Isolation of chicken phosphotyrosyl phosphatase cDNA sequences and identification of a brain-species related to human PTPz Cell Mol. Biol. Res. 39(3): 209-219. |
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Review Articles |
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Dankort D and WJ Muller. (2000) Signal transduction in mammary tumorigenesis: a transgenic perspective. Oncogene 19(8):1038-44 |
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Siegel PM, DL Dankort and WJ Muller. (2000) Oncogene mediated signal transduction in transgenic mouse models of human breast cancer. Adv Exp Med Biol 480:185-194. |
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Muller, WJ, DL Dankort, PM Siegel and MA Webster (1997) Oncogene-mediated signal transduction in transgenic mouse models of human breast cancer Endocrine-Related Cancer 4, 75-84. |
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Dankort, DL and WJ Muller (1996) Transgenic models of breast cancer metastasis In Mammary Tumor Cell Cycle, Differentiation and Metastasis, 71-88. Eds. R Dickson and ME Lippman. Kluwer Academic Publishers. |
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Articles (non-reviewed) |
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Dankort DL and WJ Muller. TKB1 cells identify receptor tyrosine kinase interacting proteins. Strategies 12(1):8-10 |
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Presentations (invited speaker) |
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Dankort, DL and WJ Muller. Genetic Dissection of Oncogeneic Neu/ErbB-2 Signaling. (1999) Cardiovascular Biology Dept., Genentech Inc. |
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Dankort, DL Warner, N Wei, Z Wang, MF Moran and WJ Muller (1998). Shc And Grb2 Play Distinct Roles In Neu/ErbB-2 Mediated Signaling. 14th Annual Oncogene Meeting , LaJolla, California. |
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Poster Abstracts |
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Dankort D, D Woods, E Venetsanakos and M McMahon (2000) Raf-induced senescence of immortalized human fibroblasts Oncogene Meeting, LaJolla, California. |
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Dankort, DL, Z Wang, MF Moran and WJ Muller (1997) Distinct tyrosine autophosphorylation sites negatively and positively modulate Neu-mediated transformation. Tyrosine Phosphorylation, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York. |
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Dankort, DL, PS Siegel and WJ Muller (1994) Genetic Identification Of The Signal Transduction Pathway(s) Involved In C-ErbB-2/Neu-Mediated Mammary Carcinogensis. Oncogene Meeting, Frederick, Maryland. |
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Dankort, DL and WJ Muller (1993) The Murine Homolog To PTP1C Is Expressed In Mammary Epithelial Cells And Associates Specifically With A Tyrosine Phosphorylated Protein In Vitro. Negative Growth Control, Keystone Symposia, Keystone, Colorado. J. Cellular Biochemistry Abstract suppl. 17A. |
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Dankort, DL and WJ Muller (1992) Identification of novel protein tyrosine phosphatases in mammary tissue by PCR amplification. Negative Growth Control, Keystone Symposia, Keystone, Colorado. J. Cellular Biochemistry Abstract suppl. 16B. |
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3/4/02 |
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