(415) 885-7878 (appts)
(415) 353-7676 (fax)

Box 1785, UCSF; San Francisco, CA 94143-1785

additional websites:

UCSF Physician Referral Directory

University of San Francisco, CA, BS, 1982, Biology
Cornell Univ. Medical College, NY, MD, 1986, Medicine
University of California San Francisco, Resident, 1986-87, Pathology
University of California San Francisco, Chief Res., 1988, Pathology

Melbye M, Smith E, Nielsen JW, Osterlind A, Orholm M, Bergmann O, Mathiesen L, DARRAGH TM, Palefsky JM: Anal and cervical abnormalities in women: Prediction by human papillomavirus tests. Int J Cancer 68:559-564, 1996.

DARRAGH TM, Jay N, Tupkelewicz BA, Hogeboom CJ, Holly EA, Palefsky JM: Comparison of conventional cytologic smears and ThinPrepÈ preparations of the anal canal. Acta Cytol 41:1167-1170, 1997.

Palefsky JM, Holly EA, Hogeboom CJ, Jay N, Berry M, DARRAGH TM: Anal cytology as a screening tool for anal squamous intraepithelial lesions. J AIDS & Hum Retrovir 14:415-422, 1997.

Jay N, Berry JM, Hogeboom CJ, Holly EA, DARRAGH TM, Palefsky JM: Colposcopic appearance of anal squamous intraepithelial lesions. Relationship to histopathology. Dis Colon Rectum 40:919-928, 1997.

Palefsky JM, Holly EA, Ralston ML, Arthur SP, Hogeboom CJ, DARRAGH TM: Anal cytologic abnormalities and anal HPV infection in men with Centers for Disease Control Group IV HIV Disease. Genitourinary Med 73:174-180, 1997.

Palefsky JM, Holly EA, Ralston ML, Arthur SP, Jay N, Berry JM, DaCosta MM, Botts R, DARRAGH TM: Anal squamous intraepithelial lesions among HIV-positive and HIV-negative homosexual and bisexual men: Prevalence and risk factors. J AIDS 17:320-326, 1998.

Palefsky JM, Holly EA, Hogeboom CJ, Ralston ML, DaCosta MM, Botts R, Berry JM, Jay N, DARRAGH TM: Viral, immunologic, and clinical parameters in the incidence and progression of anal squamous intraepithelial lesions in HIV-positive and HIV-negative homosexual men. J AIDS 17:314-319, 1998.

Palefsky JM, Holly EA, Ralston ML, Jay N, Berry JM, DARRAGH TM: High incidence of anal high-grade squamous intraepithelial lesions among HIV-positive and HIV-negative homosexual and bisexual men. AIDS 12:495-503, 1998.

Moscicki AB, Shiboski S, Broering J, Powell K, Clayton L, Jay N, DARRAGH TM, Brescia R, Karowitz S, Miller S, Stone J, Hanson E, Palefsky J: The natural history of human papillomavirus infection as measured by repeated DNA testing in adolescent women. J Pediatr 132:277-284, 1998.

Suh-Burgmann E, DARRAGH TM, Smith-McCune K: Atypical squamous cells of undetermined significance: Management patterns at an academic medical center. Am J Obstet Gynecol 178:991-995, 1998.

Smith-McCune KK, Zhu Y, DARRAGH TM: Angiogenesis in histologically benign squamous mucosa is a sensitive marker for nearby cervical intraepithelial neoplasia. Angiogenesis 2:135-142, 1998.

Moscicki AB, Burt VG, Kanowicz S, DARRAGH TM, Shiboski S: The significance of squamous metaplasia in the development of low grade squamous intraepithelial lesions of the cervix in young women. Cancer 85:1139-1144, 1999.

Moscicki AB, Ellenberg JH, Vermund SH, Holland CA, DARRAGH TM, Crowley-Nowick PA, Levin L, Wilson CM: Prevalence and risks for cervical human papillomavirus infection and squamous intraepithelial lesions in adolescent women: Impact of infection with human immunodeficiency virus. Arch Pediatr & Adolescent Med 154:127-134, 2000.

Little VR, Leavenworth JD, DARRAGH TM, Kosinski LA, Moore DH II, Smith-McCune KK, Warren RS, Palefsky JM, Welton ML: Angiogenesis, proliferation and apoptosis in anal high-grade squamous intraepithelial lesions (HSIL). Dis Colon Rectum 43:346-352, 2000.

Massad LS, Kirstein L, DARRAGH TM, Bitterman P, Sidawy M, Muderspach L, Abulafia O, Salzer E, Watts H, Melnick S: Interobserver variability in diagnosis of cervical biopsies from women with HIV-1: Results from the Women's Interagency HIV Study. J of Lower Genital Tract Disease 4:190-194, 2000.

Haga T, Kim SH, Jensen R, DARRAGH TM, Palefsky JM: Detection of genetic changes in anal intraepithelial neoplasia (AIN) of human immunodeficiency virus HIV-positive and HIV-negative men. J AIDS 26(3):256-262, 2001.

Holly EA, Ralston ML, DARRAGH TM, Greenblatt RM, Jay N, Palefsky JM: Prevalence and risk factors for anal squamous intraepithelial lesions in HIV-positive and HIV-negative women. J Natl Cancer Inst 93:843-849, 2001.

Palefsky JM, Holly EA, Ralston ML, DaCosta M, Bonner H, Jay N, Berry JM, DARRAGH TM: Effect of highly active antiretroviral therapy on the natural history of anal squamous intraepithelial lesions and anal human papillomavirus infection. J Acquir Immune Defic Syndr 28(5):422-428, 2001.

Kobayashi A, DARRAGH TM, Herndier B, Anastos K, Minkoff H, Cohen M, Young M, Levine A, Ahdieh Grant L, Hyun W, Weinberg V, Greenblatt R, Smith-McCune K: Lymphoid follicles are generated in high-grade cervical dysplasia and have differing characteristics depending on HIV stauts. Am J Pathol 160(1):151-164, 2002.

Lee KR, DARRAGH TM, Joste NE, Krane JF, Sherman ME, Hurley LB, Allred EM, Manos MM: Atypical glandular cells of undetermined significance (AGUS): Interobserver reproducibility in cervical smears and corresponding thin-layer preparations. Am J Clin Pathol 117(1);96-102, 2002.

Klencke B, Matijevic M, Urban RG, Lathey JL, Hedley ML, Berry M, Thatcher J, Weinberg V, Wilson J, DARRAGH TM, Jay N, DaCosta M, Palefsky JM: Encapsulated plasmid DNA (pDNA) treatment for HPV-16 associated anal dysplasia: A phase I study of ZYC101. Clin Cancer Res In Press, 2002.

Davey DD, Austin RM, Birdsong G, Buck H, Cox JT, DARRAGH TM, Elgert PA, Hanson V, Henry M, Waldman J: ASCCP patient management guidelines: Pap test specimen adequacy and quality indicators. J Lower Genital Tract Dis 6(2):195-199, 2002.

Klencke B, Matijevic M, Urban RG, Lathey JL, Hedley ML, Berry M, Thatcher J, Weinberg V, Wilson J, DARRAGH TM, Jay N, Da Costa M, Palefsky JM: Encapsulated plasmid DNA (pDNA) treatment for HPV-16 associated anal dysplasia: A phase I study of ZYC101. Clin Cancer Res, 8:1028-1037, 2002.

Davey DD, Austin RM, Birdsong G, Buck H, Cox JT, DARRAGH TM, Elgert PA, Hanson V, Henry M, Waldman J; American Society for Colposcopy and Cervical Pathology ASCCP patient management guidelines: Pap test specimen adequacy and quality indicators. Am J Clin Pathol, 118(5):714-718, 2002.

Robinson WR, Andersen J, DARRAGH TM, Kendall M, Clark R, Maiman M: Isotretinoin for low-grade cervical dysplasia in human immunodeficiency virus infected women. Obstet Gynecol. 99:777-781, 2002.

Moscicki, AB, Durako, SJ, Ma Y, DARRAGH T, Vermund SH: Utility of Cervicography in HIV infected and uninfected adolescents. J Adolesc Health, 32(3):204-13, 2003.

Piketty C, DARRAGH TM, Da Costa M, Bruneval P, Heard I, Kazatchkine MD, Palefsky JM: High prevalence of anal HPV infection and anal cancer precursors among HIV-infected individuals in the absence of anal intercourse. Ann Int Med, 138(6):453-9, 2003.

Moscicki AB, Durako, SJ, Houser J, Ma Y, Murphy DA, DARRAGH TM, Farhat S, Wilson CM: Human papillomavirus infection and abnormal cytology of the anus in HIV- infected and uninfected adolescents. AIDS, 17(3):311-20, 2003.

Robinson WR, Luck MB, Kendall MA, DARRAGH TM: The predictive value of cytology in HIV-infected women with low grade squamous cervical lesions: A sub-study of a randomized, phase III chemoprevention trial. Am J Obstet Gynecol, 188(4):896-900, 2003.

Durante AJ, Williams AB, Da Costa M, DARRAGH TM, Khoshnood K, Palefsky JM: Incidence of anal cytologic abnormalities in a cohort of HIV-infected women. Cancer Epidemiol Biomarkers PRev 12(7):638-42, 2003.

Ancheta E, Perry J, Bernard-Pearl L, DARRAGH T, Smith-McCune K: Participant of the ASCCP 2000 Biennial Meeting adhere to published guidelines in their management of atypia on Pap test. J Lower Genital Tract Dis, 7:279-284, 2003.

Piketty C, DARRAGH TM, Heard I, Da Costa M, Bruneval P, Kazatchkine MD, Palefsky JM: High prevalence of anal squamous intraepithelial lesions in HIV-positive men despite use of highly active antiretroviral therapy. Sex Transm Dis, 31:96-99, 2004.

11/15/04