Assistant Professor, Department of Radiation Oncology, UCSF
| CONTACT | |
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(415) 353-7175 (appts) Box 1708, UCSF; San Francisco, CA 94143-1708 |
additional websites: |
| EDUCATION | |
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University of Chicago, Chicago, IL, B.A., 1988, Chemistry
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| PROFESSIONAL EXPERIENCE | |
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1996-1997 |
Internal Medicine Internship, Kaiser Permanente Medical Center, Santa Clara, CA |
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1997-2001 |
Residency in Radiation Oncology, University of California, San Francisco. Chief Resident 1/1/2000-4/30/2000 |
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2001-present |
Assistant Professor, Department of Radiation Oncology, University of California, San Francisco |
| HONORS & AWARDS | |
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1984-88 |
Dean's List; National Science Foundation Fellowship for undergraduate research in Chemistry; National Science Foundation Graduate Fellowship, Honorable Mention; Phi Beta Kappa; B.A. with General Honors |
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1988-92 |
NIH Medical Scientist Training Program Fellowship, University of Chicago, Chicago, IL |
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1992-94 |
NIH Training Grant, Department of Molecular Genetic & Cell Biology, University of Chicago, Chicago, IL |
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1994-96 |
Medical Scientist Training Program Fellowship, University of Chicago, Chicago, IL |
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1998-99 |
NIH National Research Service Award, Department of Radiation Oncology, University of California San Francisco |
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2000 |
RSNA Research & Education Foundatin Roentgen Resident/Fellow Research Award |
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2001-02 |
Clinical Investigator Research Program Recipient, University of California San Francisco |
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August 8-9, 2002 |
Invited speaker at the Radiation Oncology Young Investigator's Symposium, Bethesda, MD, |
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2002-03 |
UCSF Prostate Cancer SPORE Delvelopmental Research Program Award |
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2002-03 |
Co-investigator on UCSF Prostate Cancer SPORE, Project 3 |
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2003-05 |
RSNA Research Scholar Award |
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2003-05 |
ASTRO Junior Faculty Award |
| SELECTED PUBLICATIONS | |
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Gottschalk AR, Joseph LJ, Quintáns J. Differential induction of Egr-1 expression in WEHI-231 sublines does not correlate with apoptosis. European Journal of Immunology 23(8): 2011-2015, 1993. |
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Gottschalk AR, McShan CL, Merino R, Nuñez G, Quintáns J. Physiological cell death in B lymphocytes: I. Differential susceptibility of WEHI-231 sublines to anti-Ig induced physiological cell death and lack of correlation with bcl-2 expression. International Immunology 6(1):121-130, 1994. |
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Gottschalk AR, Joseph LJ, Quintáns J. Fc_RII cross-linking inhibits anti-Ig-induced egr-1 and egr-2 expression in BCL1. Journal of Immunology 152(5):2115-2122, 1994. |
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Gottschalk AR, Boise LH, Thompson CB, Quintáns J. Identification of immunosuppressant-induced apoptosis in a murine B-cell line and its prevention by bcl-x but not bcl-2. Proceedings of the National Academy of Sciences of the United States of America 91(15):7350-7354, 1994. |
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Quintáns J, Kilkus J, McShan CL, Gottschalk AR, Dawson G. Ceramide mediates the apoptotic response of WEHI 231 cells to anti-immunoglobulin, corticosteroids and irradiation. Biochemical and Biophysical Research Communications 202(2):710-714, 1994. |
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Quintáns J., Bonn GA, McShan CL, Gottschalk AR. Studies on the induction of apoptosis in WEHI 231 cells by pharmacological agents and lipid mediators. Sphingosine and ceramide induce apoptosis in WEHI 231. Cell Death and Differentiation 1: 93-99, 1994. |
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Gottschalk AR, McShan CL, Kilkus J, Dawson G, Quintáns J. Resistance to anti-IgM-induced apoptosis in a WEHI-231 subline is due to insufficient production of ceramide. European Journal of Immunology 25(4):1032-1038, 1995. |
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Choi MSK, Boise LH, Gottschalk AR, Quintáns J, Thompson CB, Klaus GGB. The role of bcl-xL in CD40-mediated rescue from anti-µ-induced apoptosis in WEHI-231 B lymphoma cells. European Journal of Immunology 25(5):1352-1357, 1995. |
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Gottschalk AR, Boise LH, Oltvai ZN, Accavitti MA, Korsmeyer SJ, Quintáns J, Thompson CB. The ability of Bcl-xL and Bcl-2 to prevent apoptosis can be differentially regulated. Cell Death and Differentiation. 3:113-118, 1996. |
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Wiesner DA, Kilkus JP, Gottschalk AR, Quintáns J, Dawson G. Anti-immunoglobulin-induced apoptosis in WEHI 231 cells involves the slow formation of ceramide from sphingomyelin and is blocked by bcl-xL. Journal of Biological Chemistry 272(15):9868-9876, 1997. |
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Zundel W, Schindler C, Haas-Kogan D, Koong A, Kaper F, Chen E, Gottschalk AR, Ryan HE, Johnson RS, Jefferson AB, Stokoe D, Giaccia AJ. Loss of PTEN facilitates HIF-1-mediated geneexpression. Genes and Development 14(4):391-396, 2000. |
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Gottschalk AR, Basila D, Wong M, Dean N, Brandts CH, Stokoe D, Haas-Kogan DA. p27kip1 is required for the PTEN-induced G1 growth arrest. Cancer Research 61:2105-2111, 2001. |
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Ermoian RS, Furniss CS, Lamborn KR, Basila D, Berger MS, Gottschalk AR, Nicholas MK, Stokoe D, Haas-Kogan DA. Components of the PI3-kinase Signaling Pathway are Associated with Glioma Histology and Patient Survival. Clinical Cancer Research 8:1100-1106, 2002. |
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Langen, KM, Pouliot, J, Anezinos, C, Aubin, M, Gottschalk, AR, Hsu, IC, Lowther, D, Liu, YM, Shinohara, K, Verhey, LJ, Weinberg, V and Roach, M. Evaluation of ultrasound-based prostate localization for image guided radiation therapy. Interenational Journal of Radiation Oncology, Biology and Physics 57: 635-644, 2003. |
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Gottschalk AR and Roach M. The use of hormonal therapy with radiotherapy for prostate cancer: analysis of prospective randomized trials. British Journal of Cancer 90(5): 950-4, 2004. |
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Nakamura JL, Karlsson A, Arvold ND, Gottschalk AR, Pieper R, Stokoe D, Haas-Kogan DA. PKB/Akt meditates radiosensitization by the signaling inhibitor LY294002 in human gliomas. Submitted for publication. |
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Gottschalk AR, A. Doan A, Nakamura JL, D. A. Haas-Kogan DA and D. Stokoe D. Inhibition of PI3 kinase causes cell death through a PKB dependent mechanism and growth arrest through a PKB independent mechanism. Submitted for Publication. |
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Gottschalk AR, A. Doan A, Nakamura JL, D. A. Haas-Kogan DA and D. Stokoe D. Inhibition of phosphotidylinositol-3-kinase causes increased sensitivity to radiation through a PKB dependent mechanism. Manuscript in preparation. |
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Hsu IC, Cabrera AR, Weinberg V, Speight J, Gottschalk AR, Shinohara K. Combined Modality Treatment with High Dose Rate Brachytherapy Boost for Locally Advanced Prostate Cancer. Submitted for publication. |
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Tran QNH, Kim AC, Gottschalk AR, Wara WM, Phillips TL, O'Donnell RJ, James O. Johnston JO, Weinberg V, and Haas-Kogan DA. Clinical outcomes of intraoperative radiation therapy for extremity sarcomas. Submitted for publication. |
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Master V, Gottschalk AR, Kane C and Carroll PR. Management of patients with isolated recurrence following radical nephrectomy. Submitted for publication. |
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3/15/05 |
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