ghodgson@cc.ucsf.edu
(415) 476-3630 (voice)
(415) 476-8218 (fax)

Box 0808, UCSF; San Francisco, CA 94143-0808

additional websites:

Hodgson Lab Website

University of Guelph, Guelph, Ontario, Canada, B.Sc., 1989-1994, Molecular Biology and Genetics
University of British Columbia, Vancouver, B.C., Canada, Ph.D., 1994-1999, Medical Genetics
University of California San Francisco, CA, 1999-2002, Genomics

Hodgson JG, Smith DJ, McCutcheon K, Koide HB, Nishiyama K, Dinulos MB, Stevens ME, Bissada N, Nasir J, Kanazawa I, Disteche CM, Rubin EM, Hayden MR. (1996) Human huntingtin derived from YAC transgenes compensates for loss of murine huntingtin by rescue of the embryonic lethal phenotype. Hum Mol Genet, 5, 1875-85.

Kalchman MA, Graham RK, Xia G, Koide HB, Hodgson JG, Graham KC, Goldberg YP, Gietz RD, Pickart CM, Hayden MR. (1996) Huntingtin is ubiquitinated and interacts with a specific ubiquitin-conjugating enzyme. J Biol Chem, 271, 19385-94.

Hodgson JG, Agopyan N, Gutekunst CA, Leavitt BR, LePiane F, Singaraja R, Smith DJ, Bissada N, McCutcheon K, Nasir J, Jamot L, Li XJ, Stevens ME, Rosemond E, Roder JC, Phillips AG, Rubin EM, Hersch SM, Hayden MR. (1999) A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration. Neuron, 23, 181-92.

Leavitt BR, Guttman JA, Hodgson JG, Kimel GH, Singaraja R, Vogl AW, Hayden MR. (2001) Wild-type huntingtin reduces the cellular toxicity of mutant huntingtin in vivo. Am J Hum Genet, 68, 313-24.

Hodgson G, Hager JH, Volik S, Hariono S, Wernick M, Moore D, Nowak N, Albertson DG, Pinkel D, Collins C, Hanahan D, Gray JW. (2001) Genome scanning with array CGH delineates regional alterations in mouse islet carcinomas. Nat Genet, 29, 459-64.

Gaudet F, Hodgson JG, Eden A, Jackson-Grusby L, Dausman J, Gray JW, Leonhardt H, Jaenisch R. (2003) Induction of tumors in mice by genomic hypomethylation. Science, 300, 489-92.

Hackett CS, Hodgson JG, Law ME, Fridlyand J, Osoegawa K, de Jong PJ, Nowak NJ, Pinkel D, Albertson DG, Jain A, Jenkins R, Gray JW, Weiss WA. (2003) Genome-wide array CGH analysis of murine neuroblastoma reveals distinct genomic aberrations which parallel those in human tumors. Cancer Res, 63, 5266-73.

Verschuren EW, Hodgson JG, Gray JW, Kogan S, Jones N, Evan GI. (2004) The Role of p53 in Suppression of KSHV Cyclin-induced Lymphomagenesis. Cancer Res, 64, 581-589.

Rhee JS, Diaz R, Korets L, Hodgson JG, Coussens LM. (2004) TIMP-1 alters susceptibility to carcinogenesis. Cancer Res, 64, 952-61.

Hager JH, Hodgson JG, Fridlyand J, Hariono S, Gray JW, Hanahan D. (2004) Oncogene expression and genetic background influence the frequency of DNA copy number abnormalities in mouse pancreatic islet cell carcinomas. Cancer Res, 64, 2406-10.

Wang CL, Hodgson JG, Malek T, Pedersen FS, Wabl M. (2004) A murine leukemia virus with Cre-LoxP excisible coding sequences allowing superinfection, transgene delivery, and generation of host genomic deletions. Retrovirology, 1, 5.

Raap AK, van der Burg MJ, Knijnenburg J, Meershoek E, Rosenberg C, Gray JW, Wiegant J, Hodgson JG, Tanke HJ. (2004) Array comparative genomic hybridization with cyanin cis-platinum-labeled DNAs. Biotechniques, 37, 130-4.

Argilla D, Chin K, Singh M, Hodgson JG, Bosenberg M, de Solorzano CO, Lockett S, Depinho RA, Gray J, Hanahan D. (2004) Absence of telomerase and shortened telomeres have minimal effects on skin and pancreatic carcinogenesis elicited by viral oncogenes. Cancer Cell, 6, 373-85.

Scacheri PC, Kennedy AL, Chin K, Miller MT, Hodgson JG, Gray JW, Marx SJ, Spiegel AM, Collins FS. (2004) Pancreatic insulinomas in multiple endocrine neoplasia, type I knockout mice can develop in the absence of chromosome instability or microsatellite instability. Cancer Res, 64, 7039-44.

Hong C, Maunakea A, Jun P, Bollen AW, Hodgson JG, Goldenberg DD, Weiss WA, Costello JF. (2005) Shared epigenetic mechanisms in human and mouse gliomas inactivate expression of the growth suppressor SLC5A8. Cancer Res, 65, 3617-23.

Borowsky AD, Namba R, Young LJ, Hunter KW, Hodgson JG, Tepper CG, McGoldrick ET, Muller WJ, Cardiff RD, Gregg JP. (2005) Syngeneic mouse mammary carcinoma cell lines: two closely related cell lines with divergent metastatic behavior. Clin Exp Metastasis, 22, 47-59.

Hodgson JG, Malek T, Bornstein S, Hariono S, Ginzinger DG, Muller WJ, Gray JW. (2005) Copy number aberrations in mouse breast tumors reveal loci and genes important in tumorigenic receptor tyrosine kinase signaling. Cancer Res, 65, 9695-704.

12/7/06