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Helen Diller Family Compr Cancer Ctr
RICHARD C.K. JORDAN, DDS, PHD

Professor and Vice Chair, Department of Orofacial Sciences and Department of Pathology, UCSF
Co-Leader, Head and Neck Oncology Program, UCSF Helen Diller Family Comprehensive Cancer Center

CONTACT

rckj@itsa.ucsf.edu
(415) 476-8233 (voice)
(415) 476-6482 (fax)

Box 0424, UCSF; San Francisco, CA 94143-0424

EDUCATION

University of Toronto, D.D.S., 1986, Dentistry
University of Toronto, M.Sc., 1992, Oral Pathology
University of London (UK), Ph.D., 1995, Experimental Pathology

PROFESSIONAL EXPERIENCE

1986-1987

Intern; Toronto Western Hospital, Toronto, Canada

1987-1988

General dental practice; Newmarket, Ontario, Canada

1988-1989

Resident in anatomic pathology; Toronto Western Hospital, Toronto, Canada

1989-1991

Resident in Oral Pathology; University of Toronto

1991

Research Fellow; Canadian Reference Centre for Cancer Pathology, Ottawa, Canada

1992-1995

Medical Research Council of Canada Research Fellow, U. London, London, UK

1994

Research Fellow; Department of Haematology; Kanazawa Medical University, Kanazawa, Japan

1995-2000

Oral Pathologist; Sunnybrook & Womenęs College Health Sciences Centre, Toronto, Canada

1995-2000

Assistant Professor; Faculty of Dentistry, University of Toronto

1995-2000

Assistant Professor, Faculty of Medicine, Dept. of Lab Medicine & Pathobiology, University of Toronto

2000-2001

Associate Professor, Faculty of Dentistry, University of Toronto

2001-present

Professor & Vice Chair, Department of Orofacial Sciences & Department of Pathology, UCSF

HONORS & AWARDS

1981

Senate Scholarship, U. Western Ontario

1985

Wroblewski Award; Mosby Prize; Murray Cornish Scholarship

1986

Xi Xsi Phi prize; Deanęs Honour List

1991

U. Toronto Open Fellowship; Canadian Fund for Dental Education Award

1994

International Association of Oral Pathology Award

1995

International Association for Dental Research prize in Experimental Pathology

SELECTED PUBLICATIONS

(partial listing from 90)
* denotes corresponding author

Shahnavaz SA. Bradley G, Regezi JA, Thakker N, Gao L, Hogg D, Jordan RCK*. Patterns of CDKN2A gene loss in sequential oral epithelial dysplasias and carcinomas. Cancer Res 2001;61:2371-2375

Gstaiger M,  Jordan RCK,  Lim MS, Catzavelos C, Mestan J, Slingerland JM, Krek W. The F-box protein Skp2 is the product of an oncogene and is overexpressed in human cancers. Proc. Nat. Acad. Sci. USA 2001;98:5043-5048   denotes authors who contributed equally to this paper

Bjarnason GA, Jordan RCK, Wood PA, Lincoln D, Sothern RB, Ben-David Y. Identification of clock gene expression in human oral epithelium and skin over 24 hours. Correlation with circadian cell cycle progression. Am J Pathol 2001;158(5):1793-1801

Sanchez-Cespedes M, Parrella P, Nomoto S, Cohen D, Xiao Y, Esteller M, Jeronimo C, Jordan RCK, Nicol T, Koch WM, Schoenberg M, Mazzarelli P, Fazio VM, Sidransky D. Identification of a mononucleotide repeat as a major target for mitocondrial DNA alterations in human tumors. Cancer Res 2001;61:7015-7019

Hewitt C, Wu CL, Evcans G, Howell A, Elles RG, Jordan RCK, Sloan P, Read AP, Thakker N. Germline mutation of ARF in a melanoma kindred. Hum Mol Genetics 2002;11(11):1274-1279

Ramos DM, But M, Regezi Jam Scmidt B, Atakilit A, Dang D, Ellis D, Jordan RCK, Li X. Expression of integrin beta-6 enhances the invasive behavior of oral squamous cell carcinoma. Matrix Biol 2002;21:297-307

Macabeo-Ong M, Ginzinger DG, Dekker N, McMillan A, Regezi JA, Wong DTW, Jordan RCK*. Effect of formalin fixation time on quantitative RT-PCR expression analysis. Modern Pathology 2002;15(9):979-987

Lim MS, Adamson A, Lin Z, Perez-Ordonez B, Jordan RCK, Tripp S, Perkins SL, Elenitoba-Johnson KSJ. Expression of skp2, a p27kip1 ubiquitin ligase: correlation with p27kip1 and proliferation index in malignant lymphoma. Blood 2002;100(8):2950-2956

Regezi JA, N. Dekker, Ramos DM, Li X, Macabeo-Ong M, Jordan RCK*. Proliferation and invasion factors in HIV-associated dysplastic and non-dysplastic oral warts, and oral squamous cell carcinoma: an immunohistochemical and RT-PCR evaluation. Oral Surg Oral Med Oral Pathol 2002;94:724-731

Kim T-W, Chen Q, Shen X, Regezi JA, Ramos DM, Tanaka H, Jordan RCK, Kramer RH. Oral mucosal carcinogenesis in SENCAR mice. Anticancer Res 2002;22:2733-2740

Macabeo-Ong, Shiboski CH, Silverman S, Ginzinger DG, Dekker N, Wong DTW, Jordan RCK*. Quantitative analysis of cathepsin L mRNA and protein expression during oral cancer progression. Oral Oncol 2003;39:638-647

Zhou X, Jordan RC, Mok S, Birrer MJ, Wong DT. DNA copy number abnormality of oral squamous cell carcinoma detected with cDNA array-based comparative genomic hybridization. Cancer Genet Cytogenet. 2004 May;151(1):90-2

Baumgarth N, Szubin R, Dolganov GM, Watnik MR, Greenspan D, Da Costa M, Palefsky JM, Jordan RCK, Roederer M, Greenspan JS. Highly Tissue Substructure-Specific Effects of Human Papilloma Virus in Mucosa of HIV-Infected Patients Revealed by Laser-Dissection Microscopy-Assisted Gene Expression Profiling. Am J Pathol 2004;165(3):707-718

St John MAR, Li, Y, Zhou X, DennyP, Ho C-M, Montemagno C, Shi W, Qi F, Wu B, Sinha U, Jordan RCK, Wolinsky L, Park N-H, Abermayor E, Wong DTW. Il-6 and Il-8: Potential biomarkers for oral cancer and oropharyngeal SCC. Arch Otolaryngol H & N Surg. 2004;130:929-935

Bortoluzzi MC, Yurgel LS, Dekker NP, Jordan RCK, Regezi JA, Assessment of p63 expression in oral squamous cell carcinomas and dysplasias. Oral Surg Oral Med Oral Pathol 2004;98:698-704

Jordan RCK*, Macabeo-Ong M, Shiboski CH, Ginzinger DG, Wong DTW, Schmidt BL. Overexpression of matrix metalloproteinases-1 and 9 mRNA are associated with progression of oral dysplasia to cancer. Clin Cancer Res 2004;10:6460-6465

Li Y, St.John MAR, Zhou X, Kim Y, Sinha U, Jordan RCK, Eisele D, Abemayor E, Elashoff, Wong DTW. Salivary transcriptome diagnostics for oral cancer detection. Clin Cancer Research 2004;10(24):8442-8450

Snijders AM, Schmidt BL, Fridlyand J, Dekker N, Pinkel D, Jordan RCK, Albertson DG. Rare amplicons implicate frequent misspecification of cell fate in oral squamous cell carcinoma. Oncogene 2005 Jun 16;24(26):4232-42

Zhou X, Jordan RCK, Yang L, Huang B-L, Wong DTW. Frequent allelic imbalance at 8p and 11q22 in oral Cavity and oropharyngeal epithelial dysplastic lesions. Cancer Genet Cytogenet 2005161:86-89

1/30/07

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