Richard C.K. Jordan, DDS, PhD

University of Toronto, D.D.S., 1986, Dentistry
University of Toronto, M.Sc., 1992, Oral Pathology
University of London (UK), Ph.D., 1995, Experimental Pathology

• 1986-1987
  Intern; Toronto Western Hospital, Toronto, Canada
• 1987-1988
  General dental practice; Newmarket, Ontario, Canada
• 1988-1989
  Resident in anatomic pathology; Toronto Western Hospital, Toronto, Canada
• 1989-1991
  Resident in Oral Pathology; University of Toronto
• 1991
  Research Fellow; Canadian Reference Centre for Cancer Pathology, Ottawa, Canada
• 1992-1995
  Medical Research Council of Canada Research Fellow, U. London, London, UK
• 1994
  Research Fellow; Department of Haematology; Kanazawa Medical University, Kanazawa, Japan
• 1995-2000
  Oral Pathologist; Sunnybrook & Women's College Health Sciences Centre, Toronto, Canada
• 1995-2000
  Assistant Professor; Faculty of Dentistry, University of Toronto
• 1995-2000
  Assistant Professor, Faculty of Medicine, Dept. of Lab Medicine & Pathobiology, University of Toronto
• 2000-2001
  Associate Professor, Faculty of Dentistry, University of Toronto
• 2001-present
  Professor & Vice Chair, Department of Orofacial Sciences & Department of Pathology, UCSF

• 1981
  Senate Scholarship, U. Western Ontario
• 1985
  Wroblewski Award; Mosby Prize; Murray Cornish Scholarship
• 1986
  Xi Xsi Phi prize; Deans Honour List
• 1991
  U. Toronto Open Fellowship; Canadian Fund for Dental Education Award
• 1994
  International Association of Oral Pathology Award
• 1995
  International Association for Dental Research prize in Experimental Pathology

• (partial listing from 90)
• * denotes corresponding author
• Shahnavaz SA. Bradley G, Regezi JA, Thakker N, Gao L, Hogg D, Jordan RCK*. Patterns of CDKN2A gene loss in sequential oral epithelial dysplasias and carcinomas. Cancer Res 2001;61:2371-2375
• Gstaiger M, Jordan RCK, Lim MS, Catzavelos C, Mestan J, Slingerland JM, Krek W. The F-box protein Skp2 is the product of an oncogene and is overexpressed in human cancers. Proc. Nat. Acad. Sci. USA 2001;98:5043-5048  denotes authors who contributed equally to this paper
• Bjarnason GA, Jordan RCK, Wood PA, Lincoln D, Sothern RB, Ben-David Y. Identification of clock gene expression in human oral epithelium and skin over 24 hours. Correlation with circadian cell cycle progression. Am J Pathol 2001;158(5):1793-1801
• Sanchez-Cespedes M, Parrella P, Nomoto S, Cohen D, Xiao Y, Esteller M, Jeronimo C, Jordan RCK, Nicol T, Koch WM, Schoenberg M, Mazzarelli P, Fazio VM, Sidransky D. Identification of a mononucleotide repeat as a major target for mitocondrial DNA alterations in human tumors. Cancer Res 2001;61:7015-7019
• Hewitt C, Wu CL, Evcans G, Howell A, Elles RG, Jordan RCK, Sloan P, Read AP, Thakker N. Germline mutation of ARF in a melanoma kindred. Hum Mol Genetics 2002;11(11):1274-1279
• Ramos DM, But M, Regezi Jam Scmidt B, Atakilit A, Dang D, Ellis D, Jordan RCK, Li X. Expression of integrin beta-6 enhances the invasive behavior of oral squamous cell carcinoma. Matrix Biol 2002;21:297-307
• Macabeo-Ong M, Ginzinger DG, Dekker N, McMillan A, Regezi JA, Wong DTW, Jordan RCK*. Effect of formalin fixation time on quantitative RT-PCR expression analysis. Modern Pathology 2002;15(9):979-987
• Lim MS, Adamson A, Lin Z, Perez-Ordonez B, Jordan RCK, Tripp S, Perkins SL, Elenitoba-Johnson KSJ. Expression of skp2, a p27kip1 ubiquitin ligase: correlation with p27kip1 and proliferation index in malignant lymphoma. Blood 2002;100(8):2950-2956
• Regezi JA, N. Dekker, Ramos DM, Li X, Macabeo-Ong M, Jordan RCK*. Proliferation and invasion factors in HIV-associated dysplastic and non-dysplastic oral warts, and oral squamous cell carcinoma: an immunohistochemical and RT-PCR evaluation. Oral Surg Oral Med Oral Pathol 2002;94:724-731
• Kim T-W, Chen Q, Shen X, Regezi JA, Ramos DM, Tanaka H, Jordan RCK, Kramer RH. Oral mucosal carcinogenesis in SENCAR mice. Anticancer Res 2002;22:2733-2740
• Macabeo-Ong, Shiboski CH, Silverman S, Ginzinger DG, Dekker N, Wong DTW, Jordan RCK*. Quantitative analysis of cathepsin L mRNA and protein expression during oral cancer progression. Oral Oncol 2003;39:638-647
• Zhou X, Jordan RC, Mok S, Birrer MJ, Wong DT. DNA copy number abnormality of oral squamous cell carcinoma detected with cDNA array-based comparative genomic hybridization. Cancer Genet Cytogenet. 2004 May;151(1):90-2
• Baumgarth N, Szubin R, Dolganov GM, Watnik MR, Greenspan D, Da Costa M, Palefsky JM, Jordan RCK, Roederer M, Greenspan JS. Highly Tissue Substructure-Specific Effects of Human Papilloma Virus in Mucosa of HIV-Infected Patients Revealed by Laser-Dissection Microscopy-Assisted Gene Expression Profiling. Am J Pathol 2004;165(3):707-718
• St John MAR, Li, Y, Zhou X, DennyP, Ho C-M, Montemagno C, Shi W, Qi F, Wu B, Sinha U, Jordan RCK, Wolinsky L, Park N-H, Abermayor E, Wong DTW. Il-6 and Il-8: Potential biomarkers for oral cancer and oropharyngeal SCC. Arch Otolaryngol H & N Surg. 2004;130:929-935
• Bortoluzzi MC, Yurgel LS, Dekker NP, Jordan RCK, Regezi JA, Assessment of p63 expression in oral squamous cell carcinomas and dysplasias. Oral Surg Oral Med Oral Pathol 2004;98:698-704
• Jordan RCK*, Macabeo-Ong M, Shiboski CH, Ginzinger DG, Wong DTW, Schmidt BL. Overexpression of matrix metalloproteinases-1 and 9 mRNA are associated with progression of oral dysplasia to cancer. Clin Cancer Res 2004;10:6460-6465
• Li Y, St.John MAR, Zhou X, Kim Y, Sinha U, Jordan RCK, Eisele D, Abemayor E, Elashoff, Wong DTW. Salivary transcriptome diagnostics for oral cancer detection. Clin Cancer Research 2004;10(24):8442-8450
• Snijders AM, Schmidt BL, Fridlyand J, Dekker N, Pinkel D, Jordan RCK, Albertson DG. Rare amplicons implicate frequent misspecification of cell fate in oral squamous cell carcinoma. Oncogene 2005 Jun 16;24(26):4232-42
• Zhou X, Jordan RCK, Yang L, Huang B-L, Wong DTW. Frequent allelic imbalance at 8p and 11q22 in oral Cavity and oropharyngeal epithelial dysplastic lesions. Cancer Genet Cytogenet 2005161:86-89