Kimberly Kirkwood, MD

Reed College, Portland, OR, B.A., 1977-1981, Biology
University of Pennsylvania School of Medicine, Philadelphia, PA, M.D., 1981-1985, Medicine

• 1985-1988
  Intern/Resident, Massachusetts General Hospital, Boston, MA
• 1988-1991
  Research Fellow, UCLA School of Medicine, Los Angeles, CA
• 1991-1993
  Resident/Chief, Massachusetts General Hospital, Boston, MA
• 1993-1994
  Chief of the General Surgical Teaching Service, Massachusetts General Hospital, Boston, MA
• 1994-1994
  Attending in Trauma and General Surgery, Massachusetts General Hospital, Boston, MA
• 1994-2000
  Assistant Professor of Surgery in Residence, UCSF School of Medicine, San Francisco, CA
• 2000-present
  Associate Professor of Surgery in Residence, UCSF School of Medicine, San Francisco, CA

• 1981
  Phi Beta Kappa National Honor Society
• 1981
  Walter Croll Scholarship, University of Pennsylvania School of Medicine
• 1983-85
  President, Alpha Omega Alpha National Medical Honor Society, University of Pennsylvania Chapter
• 1989-90
  Claude E. Welch Research Fellowship Award, Department of Surgery, Mass General Hospital
• 1990-91
  Claude E. Welch Research Fellowship Award, Department of Surgery, Mass General Hospital
• 1995-96
  Nominated, Kaiser Award for Excellence in Teaching, UCSF School of Medicine
• 1996-97
  Excellence in Teaching, UCSF Department of Surgery Chief Residents
• 1998
  Clinical Teaching Award, UCSF School of Medicine, Class of 1998
• 1999
  Nominated, Kaiser Award for Excellence in Teaching, Medical Students

• Wick EC, Hoge SG, Grahn SW, Kim E, Divino LA, Grady EF, Bunnett NW, Kirkwood KS. Transient Receptor Potential Vanilloid 1, Calcitonin Gene Related Peptide and Substance P Mediate Nociception in Acute Pancreatitis, Am J Physiol Gastrointest Liver Physiol Jan/6/2006.
• Wick EC, Pikios S, Grady EF, Kirkwood KS. Calcitonin gene-related peptide partially mediates nociception in acute experimental pancreatitis, Surgery 139: 197-201, Feb/2006.
• Finzil L. Barbu V, Burgel PR, Mergey M, Kirkwood KS, Wick EC, Scoazec JY, Peschaud F, Paye F, Nadel JA, Housett C. MUCAC, a gel-forming mucin accumulating in gallstone disease, is overproduced via an epidermal growth factor receptor pathway in the human gallbladder, Am J Pathol 169: 2031-41, Dec/2006.
• Grahn S, Alvarez J, and Kirkwood KS. Trends in Laparoscopic Splenectomy for Massive Splenomegaly, Archives of Surgery 755-762, 2006.
• Ceppa E, Grahn S, Divino LA, and Kirkwood KS. The Trypsinogen Activator Enterokinase Promotes Pancreatic Inflamatory Pain, Pancreas 33: 450-451, 2006.
• Day AL, Wick E, Jordan TH, Jaffray CE, Bunnett NW, Grady EF, Kirkwood KS. Neutral endopeptidase determines the severity of pancreatitis-associated lung injury J Surg Res, Sep/2005;128(1):21-7.
• Hutter MM, Wick EC, Day AL, Maa J, Zerega EC, Richmond AC, Jordan TH, Grady EF, Mulvihill SJ, Bunnett NW, Kirkwood KS. Transient receptor potential vanilloid (TRPV-1) promotes neurogenic inflammation in the pancreas via activation of the neurokinin-1 receptor (NK-1R) Pancreas, Apr/2005;30(3):260-5.
• Lightner AM, Glasgow RE, Jordan TH, Krassner AD, Way LW, Mulvihill SJ, Kirkwood KS. Pancreatic resection in the elderly J Am Coll Surg, May/2004;198(5):697-706.
• Lightner AM, Jordan TH, Bunnett NW, Grady EF, Kirkwood KS. Recombinant human neutral endopeptidase ameliorates pancreatic elastase-induced lung injury Surgery, Aug/2002;132(2):193-9.
• Kirkwood KS, Bunnett NW, Maa J, Castagliolo I, Liu B, Gerard N, Zacks J, Pothoulakis C, Grady EF. Deletion of neutral endopeptidase exacerbates intestinal inflammation induced by Clostridium difficile toxin A Am J Physiol Gastrointest Liver Physiol, Aug/2001;281(2):G544-51.
• Maa J, Grady EF, Kim EH, Yoshimi SK, Hutter MM, Bunnett NW, Kirkwood KS. NK-1 receptor desensitization and neutral endopeptidase terminate SP-induced pancreatic plasma extravasation Am J Physiol Gastrointest Liver Physiol, Oct/2000;279(4):G726-32.
• Maa J, Grady EF, Yoshimi SK, Drasin TE, Kim EH, Hutter MM, Bunnett NW, Kirkwood KS. Substance P is a determinant of lethality in diet-induced hemorrhagic pancreatitis in mice Surgery, Aug/2000;128(2):232-9.
• Grady EF, Yoshimi SK, Maa J, Valeroso D, Vartanian RK, Rahim S, Kim EH, Gerard C, Gerard N, Bunnett NW, Kirkwood KS. Substance P mediates inflammatory oedema in acute pancreatitis via activation of the neurokinin-1 receptor in rats and mice Br J Pharmacol, Jun/2000;130(3):505-12.
• Kirkwood KS, Kim EH, He XD, Calaustro EQ, Domush C, Yoshimi SK, Grady EF, Maa J, Bunnett NW, Debas HT. Substance P inhibits pancreatic exocrine secretion via a neural mechanism Am J Physiol, Aug/1999;277(2 Pt 1):G314-20.
• Maa J, Grady EF, Kim EH, Bunnett NW and Kirkwood KS. Continuous infusion of substance P stimulates inflammatory edema in acute pancreatitis Dig Dis Sci, 1998;43(8):1889.