tkornberg@biochem.ucsf.edu
(415) 476-8821 (voice)
(415) 514-1470 (fax)

Box 2711, UCSF; San Francisco, CA 94143-2711

additional websites:

Kornberg Lab Website

Juilliard School of Music
Columbia College, B.A., 1970, Biology
Columbia University, Ph.D., 1973, Biochemistry
Princeton University, postdoctoral, 1973-1975, Biochemistry
Cambridge MRC Laboratory of Molecular Biology, postdoctoral, 1975-1976, Developmental Genetics

Tabata, T. and Kornberg, T.B. (1994) Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs. Cell 76, 89-102.

Fristrom, D., Gotwals, P., Eaton, S., Kornberg, T.B., Sturtevant, M., Bier, E., and Fristrom, J.W. (1994) blistered: a gene required for vein/intervien formation in wings of Drosophila. Development 120, 2661-2671.

Goldsborough, A.S. and Kornberg, T.B. (1994) Allele-specific amplification of Drosophila engrailed and invected transcripts. Proc. Natl. Acad. Sci. USA 91, 12696-700.

Schwartz, C., Nishida, C. and Kornberg, T.B. (1995) Regulating posterior compartment development invovles repression of cubitus interruptus expression by the engrailed protein. Development 121, 1625-1635.

Serrano, N., Demeret, C., Dura, J.M., Brock, H.W., Kornberg, T.B., and Maschat, F. (1995) polyhomeotic is a target of engrailed regulation in Drosophila. Development 121, 1691-1703.

Bourbon, H., Martin-Blanco, E., and Kornberg, T. (1995) Phosphorylation of the Drosophila engrailed protein at a site outside its homeodomain enhances DNA binding. J. Biol. Chem. 270, 11130-11139

Raeber, A.J., Muramoto, T., Kornberg, T.B., and Prusiner, S.B. (1995) Expression and targeting of Syrian hamster prion protein induced by heat shock in Drosophila melanogaster. Mech. of Development 51, 317-328.

Kuhn, D.T., Turenchalk, G., Mack, J.A., Packert, G. and Kornberg, T.B. (1995) Analysis of the genes involved in organizing the tail segments of the Drosophila melanogaster embryo. Mech. of Development 53, 3-14.

Saenz-Robles, M.T., Maschat, F., Scott, M.P. and Kornberg, T.B. (1995) Isolation and characterization of the Drosophila 110 gene, a target of engrailed regulation. Mech. of Development 53, 185-195.

Tabata, T., Schwartz, C., Gustavson, E., Ali, Z., and Kornberg, T.B. (1995) Creating a Drosophila wing de novo, the role of engrailed, and the compartment border hypothesis. Development 121, 3359-3369.

Gustavson, E., Goldsborough, A.S., Ali, Z., and Kornberg, T.B. (1996) The Drosophila engrailed and invected genes: partners in regulation, expression and function. Genetics 142, 893-906.

Goldsborough, A.G. and Kornberg, T.B. (1996) Reduction of transcription by homolog asynapsis in Drosophila imaginal discs. Nature 381, 807-810.

Aza-Blanc, P., Ramírez-Webber, F.-A., Laget, M.-P., Schwartz, C., and Kornberg. T.B. (1997) Proteolysis inhibited by Hedgehog directs Cubitus interruptus protein to the nucleus and changes its activity as a transcription regulator. Cell 89, 1043-1053.

Tsuneizumi, K. Nakayama, T., Kamoshida, Y., Kornberg, T.B., Christian, J.L. and Tabata, T. (1997) Daughters against dpp modulates dpp organizing activity in Drosophila wing development. Nature 389, 627-631.

Ramírez-Weber, F.-A. and Kornberg, T.B. (1999) Cytonemes: cellular processes that project to the principal signaling center in Drosophila imaginal discs. Cell 97, 599-607.

Aza-Blanc, P. and Kornberg, T.B. (1999) Ci, a complex transducer of the Hedgehog signal. Trends in Genetics 15, 458-462.

Casso, D., Ramírez-Weber, F.-A., and Kornberg, T.B. (1999) GFP-tagged balancer chromosomes for Drosophila melanogaster. Mech. of Development 88, 229-232.

Kornberg, T.B. and Krasnow, M.A. (2000) The Drosophila genome sequence: implications for biology and medicine. Science 287, 2218-20.

Ramírez-Weber, F.-A., Casso, D., Aza-Blanc, P., Tabata, T. and Kornberg, T.B. (2000) Hedgehog signal transduction in the posterior compartments of Drosophila wing imaginal discs. Molec. Cell 6, 479-85..

Aza-Blanc, P., Lin, H.-Y., Ruiz i Altaba, A., and Kornberg, T.B. (2000) Expression of the vertebrate Gli proteins in Drosophila reveals a distribution of activator and repressor activities. Development 127, 4293-301.

Read, D., Butte, M.J., Dernburg, A.F., Frasch, M. and Kornberg, T.B. (2000) Functional Studies of the BTB Domain in the Drosophila GAGA and Mod(mdg4) Proteins. Nucleic Acids Res. 28, 3864-70.

Chuang, P.-T. and Kornberg, T.B. (2000) On the range of Hedgehog signaling. Cur. Opin. Genet. Dev. 10, 515-22.

Llano, E., Pendas, A., Aza-Blanc, P., Kornberg, T.B. and Lopez-Otin, C. (2000) Dm1-MMP, a matrix metalloproteinase from drosophila with a potential role in extracellular matrix remodeling during neural development. J. Biol. Chem. 275, 35798-35985.

Ramírez-Weber, F.-A. and Kornberg, T.B. (2000) Signaling Reaches to New Dimensions in Drosophila Imaginal Discs. Cell 103, 189-192.

Sato M, Kornberg TB. (2002). FGF is an essential mitogen and chemoattractant for the air sacs of the drosophila tracheal system. Dev Cell. ; 3(2):195-207.

3/15/05