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Helen Diller Family Compr Cancer Ctr
AMY KRONENBERG, SCD

Deputy Head, Biophysics Dept. and Program Leader, Radiation Biology, Lawrence Berkeley Nat'l Laboratory, University of California, Berkeley

CONTACT

a_kronenberg@lbl.gov
(510) 486-6449 (voice)
(510) 486-4475 (fax)

LBNL, Mailstop: 70A-1118
1 Cyclotron Road, Berkeley, CA 94720

additional websites:

Kronenberg Lab Website, LBNL

EDUCATION

Brown University, Providence, RI, A.B., 1979, Biology
Harvard University, School of Public Health, Boston, MA, Sc.D., 1988, Cancer Biology

PROFESSIONAL EXPERIENCE

1988-present

Staff Scientist, Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA

1988-1989

Research Assistant Professor of Biophysics, University of California, Berkeley, CA

1991-present

Adjunct Faculty Member, Dept.of Radiol. Health Sci., Colorado State University, Ft. Collins, CO

1993-2012

Council Member, National Council on Radiation Protection & Measurements, Bethesda, MD

1993-2004

Member, Life Sciences Advisory Subcommittee, NASA, Washington, DC

1999-2004

Group Leader, Radiation Biology and Environmental Toxicology, Department of Cell and Molecular Biology, Life Sciences Division, Lawrence Berkeley National Lab, Berkeley, CA

2000-2008

Vice-Chair, Commission F (Life Sciences), Intl. Committee on Space Research (COSPAR)

2002-2006

Board of Directors, National Council on Radiation Protection & Measurements, Bethesda, MD

2004-present

Deputy Head, Biophysics Dept., and Program Leader, Radiation Biology, Life Sciences Division, Lawrence Berkeley National Lab, Berkeley, CA

2003-2007

Member, Radiation Therapeutics and Biology Study Section, National Institutes of Health

2005-present

Member, Exploration Systems Advisory Committee, National Aeronautics and Space Administration

Selected Teaching Experience

1994-2000

Lecturer, Advances in Radiation Biology graduate course R751, Department of Radiological Health Sciences, Colorado State University, Ft. Collins, CO.

1997, 1999, 2000

Lecturer, Human Biology 107, Astrobiology and Space Exploration, Stanford University

Fall 2001

Instructor, School of Radiobiology, Universites Paris 7 et Paris 6, Paris FRANCE.

Summer 2004-06

Lecturer, NASA Summer School in Radiation Health, Brookhaven National Lab, Upton NY

HONORS & AWARDS

2001-2005

Associate Editor, Radiation Research

2002

Invited Speaker, Symposium on Radiation Carcinogenesis in vitro and in vivo, Molecular and Cellular Aspects, Radiation Effects Research Foundation, Hiroshima, Japan

2002

Invited Speaker, State University of New York at Stony Brook Medical School, NY

2002

Organizing Cmte - Amer. Statistical Assn. Conf. on Radiation and Health, Deerfield Beach, FL

2002

External Reviewer, MRC Radiation and Genome Stability Unit, Harwell, England

2003-2007

Member, Radiation Therapeutics and Biology Study Section, National Institutes of Health, USA

2004-2006

Conference Co-Organizer, American Statistical Assn. Conf. on Radiation and Health (2006)

2004-present

Foreign Editor, Journal of Radiation Research (Japan)

2004

Invited Speaker, Yale University School of Medicine, New Haven, CT

2004

Invited Speaker, Grand Rounds, MD Anderson Cancer Center, Houston, TX

2005

Invited Plenary Speaker, European Radiation Research Society Meeting, Leicester, England

2005

Chair, Ion Beam Symposium, Radiation Research Society Meeting, Denver, CO

SELECTED PUBLICATIONS

Kronenberg, A. and Little, J.B. Molecular characterization of thymidine kinase mutants of human cells induced by densely ionizing radiation. Mutation Research 211: 215-224 (1989).

Kronenberg, A. and Little, J.B. Locus specificity for mutation induction in human cells exposed to accelerated heavy ions. Int. J. Radiat. Biol. 55: 913-924 (1989).

Kronenberg, A. Perspectives on Fast Neutron Mutagenesis in Human Cells. Radiation Res., 128: S87-S93 (1991).

Adelstein, S.J., Becker, B.B., Brooks, A.L., Kase, K.R., Kronenberg, A., McNeil, B.J., Shore, R.E., and Templeton, W.L. Identification of Research Needs For Radiation Protection. NCRP Report 117, National Council on Radiation Protection and Measurements, Bethesda, MD (1993).

Kronenberg, A. Mutation induction in human lymphoid cells by energetic heavy ions. Advances in Space Research, 14:339-346 (1994).

Kronenberg, A. Radiation-induced genomic instability. Int. J. Radiat. Biol. 66:603-609 (1994).

Kronenberg, A., and Waldren, C. Heavy ion mutagenesis: LET effects and genetic linkage. Radiat. Environ. Biophysics, 34:73-78 (1995).

Kronenberg, A., Gauny, S., Cherbonnel, C., Vannais, D., Ueno, A., Kraemer, S., and Waldren, C.A. Mechanisms of ionizing radiation-induced mutagenesis. In Radiation Research 1895-1995 (eds. U. Hagen, D. Harder, H. Jung and C. Streffer), Volume 2. Congress Lectures, Proceedings of the 10th International Congress of Radiation Research, Wurzburg, Germany, pp. 535-538 (1995).

Cherbonnel-Lasserre, C., Gauny, S., and Kronenberg, A. Suppression of apoptosis by Bcl-2 or Bcl-XL promotes susceptibility to mutagenesis. Oncogene, 13:1489-1497 (1996).

Blakely, E. A. and Kronenberg, A. Heavy-ion radiobiology: New approaches to delineate mechanisms underlying enhanced biological effectiveness. Radiation Research 150:S126-145 (1998).

Waldren, C., Vannais, D., Drabek, R., Gustafson, D., Kraemer, S., Lenarczyk, M., Kronenberg, A., Hei, T., and Ueno, U. Analysis of mutant quantity and quality in human-hamster hybrid AL and AL-179 cells exposed to 137Cs-gamma rays or HZE-Fe ions. Advances in Space Research 22(4):579-585 (1998).

Kraemer, S.M., Kronenberg, A., Ueno, A. and Waldren, C.A. Measuring the spectrum of mutations induced by nitrogen ions and protons in the human-hamster hybrid cell line ALC. Radiation Research, 153:743-751, 2000.

Grosovsky, A., Bethel, H., Parks, K., Ritter, L., Giver, C., Gauny, S., Wiese, C. and Kronenberg, A. Genomic instability in human lymphoid cells exposed to 1 GeV/amu Fe ions. Physica Medica 17:Suppl. 1, p. 240-242, 2001.

Gauny, S., Wiese, C., and Kronenberg, A. Mechanisms of mutagenesis in human cells exposed to 55 MeV protons. Physica Medica 17: Supplement 1, p. 237-239, 2001.

Wiese, C., Gauny, S., Liu, W., Cherbonnel-Lasserre, C. and Kronenberg, A. Different mechanisms of radiation-induced loss of heterozygosity in two human lymphoid cell lines from a single donor. Cancer Research 61:1129-1137, 2001.

Kraemer, S., Vannais, D.B., Kronenberg, A., Ueno, A., and Waldren C.A. Gamma-ray mutagenesis studies in a new human-hamster hybrid, ALCD59+/-, which has two human chromosomes 11 but is hemizygous for the CD59 gene. Radiation Research 156:10-19, 2001.

Wiese, C., Collins, D.W., Albala, J.S., Thompson, L.H., Kronenberg, A. and Schild, D. Interactions involving the Rad51 paralogs Rad51C and XRCC3 in human cells. Nucleic Acids Research, 30: 1009-1105, 2002.

Wiese, C., Pierce, A.J., Gauny, S.S., Jasin, M. and Kronenberg, A. Gene conversion is strongly induced in human cells by double-strand breaks and is modulated by the expression of BCL-XL. Cancer Research, 62:1279-1283,2002.

Lenarczyk, M. , Ueno, A, Vannais, D.B., Kraemer, S., Kronenberg, A., Roberts, J.R., Tatsumi, K., Hei, T.,K. and Waldren, C.A. The "pro-drug" RibCys decreases the mutagenicity of high LET radiation in cultured mammalian cells. Radiation Research 160:579-583, 2003.

Durante, M. and Kronenberg, A. Ground-based research with heavy ions for space radiation protection. Advances in Space Research 35:180-184, 2005.

5/15/06

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