Long-Cheng Li, MD

Tongji Medical University, China, MD, 1979-1984, Medicine
Tongji Medical University, China, MChir, 1988-1991, Surgery
Palermo University, Italy, Postdoc, 1997-1998, Urology
University of California, San Francisco, Postdoc, 1999-2001, Molecular Biology

• 1983 - 1984
  Intern, Medicine, Tongji Medical University (China)
• 1984-1988
  Resident, Surgery and Urology, Shashi Second Hospital, Hubei (China)
• 1989-1991
  Chief Resident, Urology, Tongji Medical University (China)
• 1991-1996
  Attending Urologist, Tongji Medical University (China)
• 2000 - 2001
  Bioinformatics Scientist, DoubleTwist, Inc., Oakland, CA
• 2001 - 2006
  Research Scientist, Urology, Northern California Institute for Research and Education (NCIRE), SF VAMC
• 2006-2007
  Assistant Researcher, Dept. of Urology, University of California San Francisco, San Francisco, CA
• 2007-2010
  Assistant Adjunct Professor, Dept. of Urology, University of California San Francisco, San Francisco, CA
• 2010-2011
  Assistant Professor, Dept. of Urology, University of California San Francisco, San Francisco, CA
• 2010-2011
  Associate Professor in Residence, Dept. of Urology, University of California San Francisco, San Francisco, CA

• 1997
  Société Internationale d'Urologie Fellowship

• Li LC, Chui R, Nakajima K, Oh BR, Au HC, Dahiya R: Frequent methylation of estrogen receptor in prostate cancer: correlation with tumor progression. Cancer Res 2000 Feb 1;60(3):702-6.
• Li LC, Chui RM, Sasaki M, Nakajima K, Perinchery G, Au HC, Nojima D, Carroll PR, Dahiya R: A single nucleotide polymorphism in the E-cadherin gene promoter alters transcriptional activities. Cancer Res 2000 Feb 15;60(4):873-6.
• Li LC, Yeh CC, Nojima D, Dahiya R. Cloning and characterization of human estrogen receptor beta promoter. Biochem Biophys Res Commun. 2000 Aug 28;275(2):682-9.
• Li LC and Dahiya R. MethPrimer: designing primers for methylation PCRs. Bioinformatics 2002;18:1-5.
• Li LC, Zhao H, Shiina H, Kane CJ and Dahiya R. PGDB: a curated and integrated database of genes related to the prostate. Nucleic Acids Research 2003, Jan 1;31(1):291-3.
• Li LC, Okino ST and Dahiya R. DNA methylation in prostate cancer. Biochim Biophys Acta Reviews on Cancer 2004 Sep 20;1704(2):87-102.
• Li LC, Shiina H, Deguchi M, Zhao H, Okino ST, Kane CJ, Carroll PR, Igawa M and Dahiya R. Age-dependent methylation of estrogen receptor alpha in prostate cancer. Biochem Biophys Res Commun 2004 Aug; 20 321(2):455-461.
• Pokot D, Li LC, Enokida H, Tabatabai ZL, Kane CJ, Carroll P, and Dahiya R. The E-cadherin -160 C/A polymorphism can predict higher risk for race-related prostate cancer. J Urol 2006 Aug;176(2):793-6.
• Li LC, Okino ST, Zhao H, Pokot D, Place RF, Dahiya R. Small double-stranded RNAs induce transcriptional activation in human cells. Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17337-17342.
• Place RF, Li LC, Pookot D, Noonan EJ, Dahiya R. MicroRNA-373 induces expression of genes with complementary promoter sequences. Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1608-13. Epub 2008 Jan 28.
• Chen Z, Place RF, Jia ZJ, Pookot D, Dahiya R, Li LC. Antitumor effect of dsRNA-induced p21WAF1/CIP1 gene activation in human bladder cancer cells. Mol Cancer Ther. 2008 Mar;7(3):698-703.
• Li LC. The multifaceted small RNAs. RNA Biol. 2008 Apr-Jun;5(2):61-4. Epub 2008 Mar 29.
• Yan TZ, Jin FS, Xie LP, Li LC. Relationship between glucocorticoid receptor signal pathway and androgen-independent prostate cancer. Urol Int. 2008;81(2):228-33. Epub 2008 Aug 29.
• Ning H, Liu G, Lin G, Garcia M, Li LC, Lue TF, Lin CS. Identification of an aberrant cell line among human adipose tissue-derived stem cell isolates. Differentiation. 2009 Feb;77(2):172-80. Epub 2008 Oct 21.
• Dharap A, Bowen K, Place R, Li LC, Vemuganti R. Transient focal ischemia induces extensive temporal changes in rat cerebral MicroRNAome. J Cereb Blood Flow Metab. 2009 Apr;29(4):675-87.
• Ning H, Huang YC, Banie L, Hung S, Lin G, Li LC, Lue TF, Lin CS. MicroRNA regulation of neuron-like differentiation of adipose tissue-derived stem cells. Differentiation. 2009 Aug 18. [Epub ahead of print]
• Lin G, Yang R, Banie L, Wang G, Ning H, Li LC, Lue TF, Lin CS. Effects of transplantation of adipose tissue-derived stem cells on prostate tumor. Prostate. 2010 Mar 15. [Epub ahead of print]
• Huang V, Qin Y, Wang J, Wang X, Place RF, Lin GT, Lue TF, Li LC. RNAa is conserved in mammalian cells. PLoS ONE. 2010 5(1): e8848. doi:10.1371/journal.pone.0008848.
• Place RF, Noonan EJ, Foldes-Papp Z and Li LC. Defining features and exploring chemical medications to manipulate RNAa activity. Current Pharm Biotech 2010 Aug;11(5):518-26.
• Noonan EJ, Place RF, Basak S, Pookot D, Li LC. miR-449a causes Rb-dependent cell cycle arrest and senescence in prostate cancer cells. OncoTarget, 2010 Sep 13;1(5):349-358.
• Wang J, Place RF, Huang V, Wang X, Noonan EJ, Magyar CE, Huang J, and Li LC. Prognostic value and function of KLF4 in prostate cancer: RNAa and vector-mediated overexpression identify KLF4 as an inhibitor of tumor cell growth and migration. Cancer Res. 2010;70:10182-10191.
• Portnoy V, Huang V, Place RF and Li, LC. Small RNA and transcriptional upregulation. WIREs RNA 2011 May 2