Staff Scientist, Lawrence Berkeley National Laboratory
| CONTACT | |
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fmarchetti@lbl.gov
Life Sciences Division, LBNL |
| EDUCATION | |
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1990, University "La Sapienza", Rome, Italy, Doctor of Biological Sciences, Cytogenetics
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| PROFESSIONAL EXPERIENCE | |
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04/06-Present |
Staff Scientist, Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA |
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02/02-04/06 |
Staff Biomedical Scientist, Bioscience Directorate, Lawrence Livermore National Laboratory, Livermore, CA. |
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5/97-02/02 |
Biomedical Scientist, Biology and Biotechnology Research Program, Lawrence Livermore National Laboratory, Livermore, CA. |
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5/94-4/97 |
Post Doctoral Staff Member, Biology and Biotechnology Research Program, Lawrence Livermore National Laboratory, Livermore, CA. |
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5/91-4/94 |
Visiting Scholar, Department of Obstetrics and Gynecology, Louisiana State University Medical Center, Shreveport, LA. |
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4/90-5/91 |
Postdoctoral Student, Department of Health Effects, ENEA, C.R.E. Casaccia, Anguillara, Italy. |
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5/88-3/90 |
Predoctoral Student, Department of Genetics, University of Rome "La Sapienza", Italy |
| HONORS & AWARDS | |
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1990 |
Summa Cum Laude, Doctoral Degree in Biological Sciences |
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1997 |
Environmental Mutagen Society International Travel Award |
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2000 |
Best Presentation, 6th Cancer Research Symposium, University of California at Davis, Medical Center |
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2000-2002 |
Member, Institutional Animal Care and Use Committee, Lawrence Livermore National Laboratory |
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2002-2006 |
Chair, Institutional Animal Care and Use Committee, Lawrence Livermore National Laboratory |
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2004-2006 |
Member, Laboratory Biosafety Operations Committee, Lawrence Livermore National Laboratory |
| SELECTED PUBLICATIONS | |
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Marchetti F, Lowe X, Moore II DH, Bishop J, and Wyrobek AJ (1996) Paternally inherited chromosomal structural aberrations detected in mouse first-cleavage zygote metaphases by multicolor FISH painting. Chromosome Research, 4, 604-613. |
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Marchetti F, Lowe X, Bishop J, and Wyrobek AJ (1997) Induction of chromosomal aberrations in mouse zygotes by acrylamide treatment of male germ cells and their correlation with dominant lethality and heritable translocations. Environmental and Molecular Mutagenesis, 30, 410-417. |
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F. Marchetti, X. Lowe, J. Bishop, A.J. Wyrobek (1999) Absence of selection against aneuploid mouse sperm at fertilization. Biology of Reproduction 61, 948-954. |
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T.E. Schmid, X. Lowe, F. Marchetti, J. Bishop, J. Haseman, A.J. Wyrobek (2001) Evaluation of inter-scorer and inter-laboratory reliability of the mouse epididymal sperm aneuploidy (m-ESA) assay. Mutagenesis 16, 189-195. |
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F. Marchetti, J.B. Bishop, X. Lowe, W.M. Generoso, J. Hozier , A.J. Wyrobek (2001) Etoposide induces heritable chromosomal aberrations and aneuploidy during male meiosis in the mouse. Proceedings of the National Academy of Sciences USA 98, 3952-3957. |
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L.M. Tomascik-Cheeseman, F. Marchetti, X. Lowe, Shamanski FL, Nath J, Pedersen R, and Wyrobek AJ (2002) CENP-B is not critical for meiotic segregation in male mice. Mutation Research 513, 197-203. |
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A.T. Christian, M.S. Pattee, F. Marchetti (2002) Meiotic chromosomes as templates for microdissection. Chromosome Research, 10, 45-48. |
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F. Pacchierotti, B. Bassani, F. Marchetti, C. Tiveron (2002) Griseofulvin induces mitotic delay and aneuploidy in bone marrow cells of orally treated mice. Mutagenesis, 17, 219-222. |
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F. Marchetti, A.J. Wyrobek (2003) PAINT/DAPI analysis of mouse zygotes to detect paternally transmitted chromosomal aberrations. Advances in Experimental Medicine and Biology, 518, 131-145. |
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Hill F*, Marchetti F*, Liechty M, Bishop J, Hozier J, Wyrobek AJ (2003) A new FISH assay to simultaneously detect structural and chromosomal abnormalities in mouse sperm. Molecular Reproduction and Development 66, 172-180. *These authors contributed equally to this work. |
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Marchetti F, Bishop J, Cosentino L, Moore Dan II and Wyrobek AJ (2004) Paternally transmitted chromosomal aberrations in zygotes determine their embryonic fate. Biology of Reproduction 70, 616-624; Epub 2003 Oct 29. |
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Schmid TE, Brinkworth MH, Hill F, Sloter ED, Kamischke A, Marchetti F, Nieschlag E, Wyrobek AJ (2004) Detection of structural and numerical chromosomal abnormalities by multicolor-FISH analysis in sperm of oligozoospermic infertility patients. Human Reproduction, 19:1395-1400; Epub 2004 April 29. |
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Tomascik-Cheeseman LM, Coleman MA, Marchetti F, Nelson D, Kegelmeyer LM, Nath J, Wyrobek AJ (2004) Differential basal expression of genes associated with stress response, damage recognition and DNA repair among healty mouse tissues. Mutation Research, 561, 1-14. |
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Zudova D, Wyrobek AJ, Bishop J, Marchetti F (2004) Impaired fertility in T-stock female mice after superovulation. Reproduction, 128, 573-581. |
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Wyrobek AJ, Schmid TS, Marchetti F (2005) Cross-species sperm-FISH assays for chemical testing and assessing paternal risk for chromosomally abnormal pregnancies. Environmental and Molecular Mutagenesis, 45:271-283; Epub 2005, March 7. |
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Wyrobek AJ, Schmid TE, Marchetti F (2005) Relative susceptibilities of male germ cells to genetic defects induced by cancer chemotherapies. Journal of the National Cancer Institute Monographs, 34, 31-35. |
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Marchetti F, Wyrobek AJ (2005) Mechanisms and consequences of paternally transmitted chromosomal abnormalities. Birth Defects Research, Part C, Embryo Today 75, 112-129. |
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Mailhes JB, Marchetti F (2005) Mechanisms and chemical induction of aneuploidy in rodent germ cells. Cytogenetic and Genome Research, 111, 384-391. |
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Marchetti F, Pearson F, Bishop JB, Wyrobek AJ (2006) Etoposide induces chromosomal abnormalities in mouse spermatocytes and stem cell spermatogonia. Human Reproduction, 21, 888-895. Epub: November 25, 2005. |
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6/19/06 |
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