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Helen Diller Family Compr Cancer Ctr
WALLACE MARSHAL, PHD

Assistant Professor in Residence, Biochemistry and Biophysics, UCSF

CONTACT

wmarshall@biochem.ucsf.edu
(415) 514-4304
(415) 502-4315 (fax)

Box 2200, San Francisco, CA 94143-2200

EDUCATION

State University of New York at Stony Brook, BE, 1991, Electrical Engineering
State University of New York at Stony Brook, BS, 1991, Biochemistry
University of California, San Francisco, PhD, 1997, Biochemistry
Yale University, New Haven CT, Postdoc, 1997-2003, Cell Biology

PROFESSIONAL EXPERIENCE

2003 - present

Assistant Professor of Biochemistry, UCSF

HONORS & AWARDS

2005 - 2008

Searle Scholar Award

2000 - 2003

Leukemia & Lymphoma Society Special Fellowship

1997 - 2000

Helen Hay Whitney Foundation Fellowship

1991 - 1996

Howard Hughes Medical Institute Predoctoral Fellowship

SELECTED PUBLICATIONS

Marshall, W.F., Dernburg, A.F., Harmon, B., Agard, D.A., and Sedat, J.W. 1996. Specific interactions of chromatin with the nuclear envelope: Positional determination within the nucleus in Drosophila melanogaster. Molecular Biology of the Cell 7,825-42.

Dernburg, A.F., Broman, K.W., Fung, J.C., Marshall, W.F., Philips, J., Agard, D.A., and Sedat, J.W. 1996. Perturbation of nuclear architecture by long-distance interactions. Cell 85,745-759.

Marshall, W.F., Straight, A.F., Marko, J., Dernburg, A.F., Swedlow, J.R., Murray, A., Belmont, A., Agard, D.A., and Sedat, J.W. 1997. Interphase chromatin undergoes constrained diffusional motion in living cells. Current Biology 7,930-939.

Straight, A.F., Marshall, W.F., Sedat, J.W., and Murray, A.W. 1997. Mitosis in living budding yeast: anaphase A but no metaphase plate. Science 277,574-578.

Bass, H.W., Marshall, W.F., Sedat, J.W., Agard, D.A., and Cande, W.Z. 1997. Telomeres cluster de novo before the initiation of synapsis: a three-dimensional spatial analysis of telomere positions before and during meiotic prophase. J. Cell Biol. 137,5-18.

Oegema, K., Marshall, W.F., Sedat, J., and Alberts, B. 1997. Two proteins that cycle asynchronously between centrosomes and nuclear structures: Drosophila CP60 and CP190. J. Cell Sci. 110,1573-1583.

Nunnari, J., Marshall, W.F., Straight, A., Murray, A., Sedat, J.W., and Walter, P. 1997. Mitochondrial transmission during mating in Saccharomyces cerevisiae is determined by mitochondrial fusion and fission and the intramitochondrial segregation of mitochondrial DNA. Molecular Biology of the Cell 8,1233-1242.

Fung, J.C., Marshall, W.F., Dernburg, A.F., Agard, D.A., and Sedat, J.W. 1998. Homologous chromosome pairing in Drosophila melanogaster proceeds through multiple independent initiations. J. Cell Biol. 141,5-20.

Marshall, W.F., Marko, J.F., Agard, D.A., and Sedat, J.W. 2001. Chromosome elasticity and mitotic polar ejection force measured in living Drosophila embryos using four-dimensional microscopy-based motion analysis. Curr. Biol. 11,569-578.

Marshall, W.F. and Rosenbaum, J.L. 2001. Intraflagellar transport balances continuous turnover of outer doublet microtubules: implications for flagellar length control. J. Cell Biol. 155,405-414.

Marshall, W.F., Vucica, Y, and Rosenbaum, J.L. 2001. Kinetics and regulation of de novo centriole assembly: implications for the mechanism of centriole duplication. Curr. Biol. 11,308-317.

Zamora, I., Feldman, J.L., and Marshall, W.F. 2004. PCR-based assay for mating type and diploidy in Chlamydomonas reinhardtii. Biotechniques. 37,534-535.

Marshall, W.F. 2004. Human ciliary proteome contains a homolog of the zebrafish polycystic kidney disease gene qilin. Curr. Biol. 14,R913-914.

Marshall, W.F., Qin, H., Rodrigo Brenni, M., and Rosenbaum, J.L. 2005. Flagellar length control system: testing a simple model based on intraflagellar transport and turnover. Mol. Biol. Cell 16,270-278.

Stolc, V., Samanta, M.P., Tongprasit, W., and Marshall, W.F. 2005. Genome-wide transcriptional analysis of flagellar regeneration in Chlamydomonas reinhardtii identifies orthologs of ciliary disease genes. Proc. Natl. Acad. Sci. U.S.A. 102,3703-3707.

Zamora, I., and Marshall, W.F. 2005. A mutation in the centriole-associated protein centrin causes genomic instability via increased chromosome loss. BMC Biology. 3,15.

Keller, L.C., Romijn, E.P., Zamora, I., Yates, J.R. 3rd., and Marshall, W.F. 2005. Proteomic analysis of isolated Chlamydomonas centrioles reveals orthologs of ciliary disease genes. Curr. Biol. 15,1090-8.

Nonaka, S., Yoshiba, S., Goto, T., Marshall, W.F., and Hamada, H. 2005. De novo formation of left-right asymmetry by posterior tilt of nodal cilia. PloS Biology. 3,e268

Kennedy, T.E., Wang, H., Marshall, W.F., and Tessier-Lavigne, M. 2006. Axon guidance by diffusible chemoattractants: a gradient of netrin protein in the developing spinal cord. J. Neurosci. 26,8866-74.

Feldman, J.L, Geimer, S., and Marshall, W.F. 2007. The mother centriole plays an instructive role in defining cell geometry. PLoS Biology. 5,e149.

7/6/07

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