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Helen Diller Family Compr Cancer Ctr
SARAH J. NELSON, PHD

Margaret Hart Surbeck Distinguished Professor of Advanced Imaging, UCSF
Director, Surbeck Laboratory of Advanced Imaging
Chair, Division of Bioengineering, UCSF

CONTACT

sarah.nelson@radiology.ucsf.edu
(415) 514-9242 (Asst), 476-6383 (office)
(415) 476-6022 (fax)

Box 0775, UCSF; San Francisco, CA 94143-0775

EDUCATION

University of Manchester, England, Hons. B.S., 1975, Mathematics
University of Heidelberg, West Germany, Dr.rer.Nat., 1982, Applied Math/Rad. Biol.
Fox Chase Cancer Center, Philadelphia, PA, Postdoc, 1985-87, NMR

PROFESSIONAL EXPERIENCE

1975-1978

Systems Analyst/Applied Mathematician, EASAMS Ltd., Surrey, England

1978

Mathematics Teacher, Geroge Abbott School, Surrey, England

1979-1982

Research Fellow / Graduate Student of Special Research. Project 123 "Stochastic Mathematical Models." Department of Applied Mathematics, University of Heidelberg, West Germany

1985-1987

Postdoctoral Fellow, Biostatistics Laboratory, Fox Chase Cancer Center, Philadelphia, PA

1987-1988

Research Associate of NMR and Medical Spectroscopy, Fox Chase Cancer Center, Phila. PA

1988-1990

Associate Member, Dept. of NMR and Medical Spectroscopy, Fox Chase Cancer Center Phila. PA

1990-1994

Assistant Professor of Radiology, University of California, San Francisco, CA

1995-1997

Associate Director, Magnetic Resonance Science Center, UCSF, CA

1994-2000

Associate Professor of Radiology, University of California, San Francisco, CA

1997-2003

Scientific Director, Magnetic Resonance Science center, UCSF, CA

1999-2001

Visiting Professor of Bioengineering, University of California, Berkeley, CA

2000-present

Professor of Radiology, University of California, San Francisco. CA.

2002-present

Professor of Bioengineering, University of California, Berkeley CA.

2002-present

Chair, Division of Bioengineering, University of California, San Francisco, CA

2003-present

Director, Surbeck Laboratory of Advanced Imaging, University of California, San Francisco, CA

2004-present

Margaret Hart Surbeck Distinguished Professorship in Advanced Imaging, University of Califonria, San Francisco, CA.

2005-present

Director, Program in Bioengineering of UCSF School of Medicine, UCSF, CA

SELECTED PUBLICATIONS

(from 116 total)

Nelson, SJ. Multivoxel magnetic resonance spectroscopy of brain tumors. Oncology Spectrums 3:6 2002.

Fischbein NJ, Noworolski SM, Henry RG, Kaplan MJ, Dillon WP, Nelson, SJ. Assessment of metastatic cervical adenopathy using dynamic contrast-enhanced MR imaging. Am J Neuroradiol 24(3):301-311, 2003.

Srinivasan R, Henry R, Pelletier D, Nelson S. Standardized, Reproducible, High Resolution Global Measurements of T1 Relaxation Metrics in Multiple Sclerosis. Am J Neuroradiol 2003 24:58-67.

Nelson SJ, Cha S. Imaging glioblastoma multiforme, The Cancer Journal 9(2):134-145, 2003.

Pelletier D, Nelson SJ, Oh J, Antel JP, Kita M, Zamvil SS, Goodkin DE. MRI lesion volume heterogeneity in primary progressive MS in relation with axonal damage and brain atrophy. J Neurol Neurosurg Psychiatry 74:1-4, 2003.

Nelson SJ. Multivoxel magnetic resonance spectroscopy of brain tumors. Mol Can Therapeutics May 2(5):497-507, 2003.

Mohr DC, Epstein, L. Luks, TL, Goodkin D, Cox D, Goldberg A, Chin C, Nelson SJ. Brain lesion volume and neuropsychological function predict efficacy of treatment for depression in multiple sclerosis. J Consult Clin Psychol 71(6): 1017-1024, 2003.

Lee M, Pirzkall A, Akazawa P, Verhey LJ, Nelson SJ. MR spectroscopy of radiation effects in healthy brain tissue following radiotherapy. Int J Radiat Oncol Biol Phys 57(S):133-134, 2003

Oh J, Henry RG, Pirzkall A, Lu Y, Li X, Catalaa I, Chang S, Dillon WP, Nelson SJ. Survival analysis in patients with glioblastoma multiforme: predictive value of choline to N-acetylaspartate index, apparent diffusion coefficient and relative cerebral blood volume. J Magn Reson Imaging 19:546-554, 2004

Lee MC, Pirzkall A, McKnight T, Nelson SJ, 1H-MRSI of Radiation Effects in Normal-appearing white matter: dose-dependence and impact on automated spectral classification. J Magn Reson Imag. 19(4):379-388, 2004.

R. Hurd, S. Napapon, R. Srinivasan, D. Vigneron, D. Pelletier, S. Nelson, Measurement of Brain Glutamate using TE-averaged PRESS at 3T. Magn Reson Med, 51(3):435-440, 2004.

R. Srinivasan, D. Vigneron, S. Napapon, R. Hurd, N. SJ, Comparative study of Myo-inositol quantification using LC model at 1.5T and 3.0T with 3D 1H Proton Spectroscopic Imaging of the Human Brain. J Magn Reson Imaging 22(4):523-528, 2004.

Pirzkall, X. Li, J. Oh, S. Chang, M.S. Berger, M.W. McDermott, D.A. Larson, L.J. Verhey, W.P. Dillon, S.J. Nelson, Ò3D MR-Spectroscopy for Resected High-Grade Gliomas Prior to RT: Tumor Extent according to Metabolic Activity in Relation to MRIÓ, Int J Radiat Oncol Biol Phys 59(1):126-137, 2004.

Li X, Jin H, Lu Y, Oh J, Chang S, Nelson SJ. Identification of MRI and 1H MRSI parameters that may predict survival for patients with malignant gliomas. NMR Biomed, 17(1):10-20, 2004.

Oh J, Henry RG, Genain C, Nelson SJ, Pelletier D. Mechanisms of normal appearing corpus callosum injury related to pericallosal T1 lesions in multiple sclerosis using directional diffusion tensor and 1H MRS imaging. J Neurol Neurosurg Psychiatry 75:1281-1286, 2004.

Oh J, Pelletier D, Nelson SJ, Preferential Corpus Callosum Axonal Injury in Multiple Sclerosis Measured by Proton Magnetic Resonance Spectroscopic Imaging, Arch. Neurology, 61(7): 1081-1086.2004.

Chan, AA, Lau, A, Pirzkall, A, Chang SM, Verhey LJ, Larson, D, McDermott, M, Dillon, W, Nelson SJ, Proton Magnetic Resonance Spectroscopic Imaging as a tool for evaluating grade IV glioma patients undergoing gamma knife radiosurgery, J. Neurosurgery, 101(3):467-475, 2004.

Nelson, SJ. MR Imaging and Spectroscopy, Engineering in Medicine and Biology Special Issue on Molecular Imaging, Sept-Oct (2), 2004.

Arias-Mendoze F, Zakian K, Schwartz A, Howe FA, Koutcher JA, Leache MO, Griffiths JR, Heerschap A, Glickson JD, Nelson SJ, Evelhoch JL, Charles HC, Brown TR: Cooperative Group on MRS Applications in Cancer. Methodological standardization for a multi-institutional in vivo trial of localized 31P MR spectroscopy in human cancer research: In vitro and normal volunteer studies. NMR Biomed, 17(6):382-391; 2004

Oh J, Cha S, Aiken AH, Han ET, Crane JC, Stainsby JA, Wright GA, Dillon WP, Nelson SJ. Quantitative apparent diffusion coefficients and T2 relaxation times in characterizing contrast enhancing brain tumors and regions of peritumoral edema. J Magn Reson Imag 21(6):701-708, 2005.

Cha S, Tihan T, Crawford F, Fischbein NJ, Chang S, Bollen A, Nelson SJ, Prados M, Berger MS, Dillon WP. Differentiation of low-grade oligodendrogliomas from low-grade astrocytomas by using quantitative blood-volume measurements derived from dynamic susceptibility contrast-enhanced MR imaging. AJNR Am J Neuroradiol. 26:266-273, 2005.

Li X, Vigneron DB, Cha S, Graves EE, Crawford F, Chang S, Nelson SJ. Relationship of MR-derived lactate, mobile lipids and relative blood volume for gliomas in vivo. Am J Neuroradiol, 26:760-769, 2005.

Srinivasan R, Sailasuta N, Hurd R, Nelson SJ, Pelletier D. Evidence of elevated glutamate in multiple sclerosis using magnetic resonance spectroscopy at 3 T. Brain 128:1016-1025, 2005.

Lee MC, Chang SM, Cha S, Nelson SJ. Dynamic susceptibility contrast perfusion imaging of radiation effects in normal appearing brain tissue: changes in the first-pass and recirculation phases, in press J Magn Reson Imag, 19(2):123-129, 2005.

Lupo JM, Cha S, Sadarangani P, Chang S, Nelson SJ, Dynamic susceptibility-weighted perfusion imaging of high-grade gliomas: characterization of spatial heterogeneity. Am J Neuroradiol, 26(6): 1446-1454, 2005.

Zektzer AS, Swanson MG, Jarso S, Nelson SJ, Vigneron DB, Kurhanewicz J. Improved signal to noise in high-resolution magic angle spinning total correlation spectroscopy studies of prostate tissues using rotor-synchronized adiabatic pulses. Magn Reson Med. 2005 Jan;53(1):41-8.

Lee MC, Cha S, Chang SM, Nelson SJ. A Partial-volume Model for Determining White Matter and Gray Matter Cerebral Blood Volume for Analysis of Gliomas. J Magn Reson Imaging. Feb 2, 2006.

12/8/06

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