Assistant Professor, Pathology, UCSF
| CONTACT | |
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scott.oakes@ucsf.edu Box 0511, UCSF; San Francisco, CA 94143-0511 |
| EDUCATION | |
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Elmira College, Elmira, NY, B.A., 1993, Biochemistry
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| PROFESSIONAL EXPERIENCE | |
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1995-1996 |
Research Scholar, HHMI, Lymphocyte Cell Biology Section, National Institute of Arthritis, Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD. Advisor: John J. O'Shea, M.D. |
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1998-2000 |
Resident, Anatomic Pathology, Brigham and Women's Hospital, Boston, MA |
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1998-2002 |
Clinical Fellow in Pathology, Harvard Medical School, Boston, MA |
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2000-2005 |
Research Associate, Department of Cancer Immunology & AIDS, Dana-Farber Cancer Institute, Boston, MA. Advisor: Stanley J. Korsmeyer, M.D. |
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2002-2005 |
Instructor in Pathology, Harvard Medical School, Boston, MA. |
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2005-present |
Assistant Professor, Department of Pathology, University of California San Francisco |
| HONORS & AWARDS | |
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1989 |
Salutatorian Scholarship |
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1990 |
Borden Highest Freshman GPA Prize |
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1991 |
Phi Beta Kappa Prize |
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1992 |
Phi Beta Kappa Prize |
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1992 |
Gorman Prize for Most Scholarly Work in Chemistry |
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1993 |
Outstanding Senior Chemistry Award |
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1993 |
Elmira College Valedictorian |
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1998 |
American Endocrine Society Award |
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1998 |
American Endocrine Society Award |
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2000-2003 |
NIH Pathology Training Grant Recipient |
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2003-2008 |
NIH Mentored Clinical Scientist Development Award (K08) |
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2006-2007 |
American Cancer Society Junior Investigator Award |
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2007-2009 |
HHMI Early Career Physician Scientist Award |
| SELECTED PUBLICATIONS | |
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Johnston JA, Wang LM, Hanson EP, Sun XJ, White MF, Oakes SA, Pierce JH, O'Shea JJ. Interleukins 2, 4, 7, and 15 stimulate tyrosine phosphorylation of insulin receptor substrates 1 and 2 in T cells. Potential role of JAK kinases. J. Biol. Chem. 1995;270:28527-28530. | |
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Candotti F, Oakes SA, Johnston JA, Notarangelo LD, O'Shea JJ, Blaese RM. In vitro correction of JAK3-deficient severe combined immunodeficiency by retroviral-mediated gene transduction. J. Exp. Med. 1996;183:2687-2692. | |
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Oakes SA, Candotti F, Johnston JA, Chen YQ, Ryan JJ, Taylor N, Lui X, Hennighauser L, Notarangelo LD, Paul WE, Blaese RM, O'Shea JJ. Signaling via IL-2 and IL-4 in JAK3-deficient severe combined immunodeficiency lymphocytes: JAK3-dependent and -independent pathways. Immunity 1996;5:605-615. | |
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Taylor N, Candott F, Smith S, Oakes SA, Jahn T, Isakov J, Puck JM, O'Shea JJ, Weinberg K, Johnston JA. Interluekin-4 signaling in B lymphocytes from patients with X-linked severe combined immunodeficiency. J. Biol. Chem. 1997;272:7314-7319. | |
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Candotti F, Oakes SA, Johnston JA, Giliani S, Schumacher RF, Mella P, Fiorini M, Ugazio AG, Badolato R, Notarangelo LD, Bozzi F, Macchi P, Strina D, Vezzoni P, Blaese RM, O'Shea JJ, Villa A. Structural and functional basis for JAK3-deficient severe combined immunodeficiency. Blood 1997;90:3996-4003. | |
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Scorrano L, Ashiya M, Buttle K, Weiler S, Oakes SA, Mannella CA, Korsmeyer SJ. Distinct pathways remodel mitochondrial cristae or release cytochrome c during apoptosis. Dev. Cell 2002;2:55-67. | |
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Scorrano L*, Oakes SA*, Opferman JT, Cheng EH, Sorcinelli MD, Pozza T, Korsmeyer SJ. BAX and BAK regulation of endoplasmic reticulum Ca2+:a control point for apoptosis. Science 2003;300:135-139. *These authors contributed equally. | |
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Bassik MC, Scorrano L, Oakes SA, Pozzan T, Korsmeyer SJ. Phosphorylation of BCL-2 regulates ER Ca2+ homeostasis and apoptosis. EMBO J. 2004;23:1207-1216. | |
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Oakes SA, Scorrano L, Opferman JT, Bassik MC, Nishino M, Pozzan T, Korsmeyer SJ. Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum. Proc. Natl. Acad. Sci. USA. 2005;102:105-110. |
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12/11/06 |
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