Claudia Petritsch, PhD
Assistant Professor, Brain Tumor Research Center and Department of Neurological Surgery; and Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, UCSF
Contact
.(JavaScript must be enabled to view this email address)
(415) 514-9785 (office); (415) 514-4990 (lab)
(415) 514-9791 (fax)
Box 0520, UCSF; San Francisco, CA 94143-0520
Education
University of Vienna BioCenter, Vienna, MS, BA, 1985 -1991, Cell and Molecular Biology and Biochemistry
University of Vienna BioCenter, Vienna, PhD, 1991-1996, Cell & Molecular Biology
Institute of Molecular Pathology, Vienna, Postdoc, 1996-1997
University of California, San Francisco, Dept of Physiology, Postdoc, 1997-2002
Professional Experience
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2002-2003
Postgraduate Researcher, Department of Physiology, University of California, San Francisco
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2003-2005
Investigator, GeneCenter and Institute of Biochemistry at the University of Munich
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2005-2008
Associate Research Biochemist, Department of Neurological Surgery, University of California, San Francisco
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2008-present
Assistant Professor, Brain Tumor Research Center and Department of Neurological Surgery, University of California, San Francisco
Honors & Awards
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1990
Diploma Fellowship, Institute of Molecular Pathology
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1991-96
PhD Fellowship, Institute for Molecular Pathology
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1993
European Molecular Biology Organisation short-term fellowship
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1994
Federation of European Biochemical Societies short-term fellowship
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1996
European Molecular Biology Organisation long-term fellowship
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1999
Human Frontiers Science Program Organization long-term fellowship
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2003
PO 1 Research Grant; German Research Council (DFG) # SFB 413
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2004
PO 1 Research Grant; German Research Council (DFG) # SFB 413
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2004-06
Award for Outstanding Women in Life Sciences (University of Munich)
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2005-06
Bavarian California Technology Award
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2006
California Breast Cancer Research Program/CBRCP, IDEA Award, San Francisco, USA
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2007-2008
National Brain Tumor Foundation, Oligodendroglioma Award, San Francisco, USA
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2007-2008
Brain Tumor SPORE, Career Development Research Award, San Francisco, USA
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2010
American Brain Tumor Association, Discovery Award, Des Plaines, USA
Selected Publications
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Petritsch C., Beug H., Balmain A. and Oft M.: TGFbeta inhibits p70 S6 Kinase via Protein Phosphatase 2A to induce G1 arrest. Genes & Dev. 14, 3093-3101 (2000). PMCID: PMC317138
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Petritsch C., Tavosanis, G., Turck, CW., Jan, LY. and Jan YN. (2003). The Drosophila myosin VI Jaguar controls spindle orientation and basal determinant targeting in mitotic neuroblasts. Developmental Cell. 4, 273-281.
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Ye B, Petritsch C., Clark, I. E., Gavis, E. R., Jan LY. and Jan YN. (2004). nanos and pumilio, two genes known for translational regulation of embryonic body patterning, are essential for proper dendrite morphogenesis in Drosophila peripheral neurons. Current Biology. 14, 314-21.
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Waldhuber, M., Emoto, K. and Petritsch, C. The Drosophila caspase DRONC is required for metamorphosis and cell death in response to irradiation and developmental signals. Mech. Dev. 122 (7-8), 914-27 (2005)
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Erben, V., Waldhuber, M, Langer, D., Fetka, I, Jansen, R. P., Petritsch, C. (2008). Asymmetric localization of the adaptor protein Miranda is achieved by diffusion and sequential interaction of Myosin II and VI. Journal of Cell Science (121).
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Silber, J., Lim, D.A., Petritsch, C.*, Maunakea, A. K.*, Persson, A.*, Yu, M., Vandenberg, S., Ginzinger, D. G., James, C. D., Costello, J. F., Weiss, W. A., Bergers, G., Alvarez-Buylla, A., Hodgson, G. (2008). miR-124a and miR-137 inhibit proliferation of GBM cells and induce differentiation of tumor stem cells." (*authors contributed equally), BioMedCentral Medicine 6:14. PMCID: PMC2443372
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Du, R., Petritsch, C., Ganss, R., Song, H., Vandenberg, S., Bergers, G. (2008). Matrix metalloproteinase 2 regulates tumor cell survival, invasion and vascular branching in GBM. Neuro-oncology, 10(3):254-64. PMCID: PMC2563048
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Du, R.*, Lu, K.*, Petritsch, C., Liu, P., Ganss, R., Passague, E., Song, H., VandenBerg, S., Werb, Z., Bergers, G. (2008). Hif1a induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion. (*authors contributed equally), Cancer Cell (3), 206-20. PMCID: PMC2643426
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Persson, A., Petritsch, C., Itsara, M., Swartling, F., Goldenberg, D., Vandenberg, S., Ngyuen, K., Yakovenko, S., Thorne, C.A., Lee, E., Nishiyama, A., Stallcup, W., Berger, M.S., Goldman, S., Bergers, G., Weiss, W.A. (2010). Non-stem cell origin of oligodendondrogliomas. In Press. Cancer Cell.
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Sugiarto, S, Persson, A., Gonzalez-Munoz, E., Waldhuber, M., Lamagna, C., Hanecker, P., Philips, J., Vandenberg, S., Berger, M. S., Stallcup, W., Bergers, G., Weiss, W. A., Petritsch, C. (2010) Asymmetry-defective oligodendrocyte progenitors as glioma precursors. In revision. Cancer Cell
Updated: November 4, 2010