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Manish K. Aghi, MD, PhD

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
aghi_manish

Assistant Professor in Residence, Department of Neurological Surgery, UCSF

Phone: (415) 353-7500 (appts)
Box 0112, UCSF
San Francisco, CA 94143-0112

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Additional Websites


Education

Stanford University (Stanford, CA), BS, 1993, Biological Sciences
Stanford University (Stanford, CA), MS, 1993, Biological Sciences
Harvard Medical School (Boston, MA), MD, 2000, Medicine
Harvard Medical School (Boston, MA), PhD, 2000, Neuroscience

Professional Experience

  • 2000-2001
    Intern, General Surgery, Massachusetts General Hospital, Boston, MA
  • 2001-2007
    Resident, Neurosurgery, Massachusetts General Hospital, Boston, MA
  • 2007
    Assistant Professor, Neurosurgery, Massachusetts General Hospital, Boston, MA
  • 2008-present
    Assistant Professor in Residence, Neurosurgery, University of California, San Francisco, CA

Honors & Awards

  • 2004
    Preuss Award, best basic science brain tumor research, American Association of Neurologic Surgeons (AANS) meeting, "Generation of Brain Tumor Neovasculature from Transplanted Bone Marrow."
  • 2005
    Ronald L. Bittner Award, best brain tumor research, American Association of Neurologic Surgeons (AANS) meeting
  • 2005
    William Scoville Resident Research Award, New England Neurosurgery meeting, "Generation of Glioma Neovasculature from Transplanted Bone Marrow."
  • 2005
    Congress of Neurologic Surgeons (CNS) Resident Research Award, "Enhanced Replication of Oncolytic HSV in Glioma Cells that Evade Temozolomide Chemotherapy Through DNA Repair."
  • 2005
    American Academy of Neurologic Surgeons Resident Research Award, "Stromal Derived Factor-1 Interacts with Environmental Cues to Induce Bone Marrow-Derived Cells to Differentiate into Tumor Endothelium and Pericytes."
  • 2006
    Mahaley Award, best clinical study in neuro-oncology, presented at American Association of Neurologic Surgeons (AANS) meeting
  • 2006
    Integra Foundation Award, best benign brain and peripheral nerve tumor research, presented at Congress of Neurologic Surgeons (CNS) meeting
  • 2007
    Synthes Skull Base Award, Congress of Neurologic Surgeons (CNS) meeting
  • 2009
    American Brian Tumor Association (ABTA) Young Investigator Award, Congress of Neurological Surgeons (CNS) meeting

Selected Publications

  1. Castro BA, Aghi MK. Getting more out of radiation therapy in glioblastoma. Neuro Oncol. 2014 Jan; 16(1):4-6.
    View on PubMed
  2. Jahangiri A, Aghi MK, Carbonell WS. ß1 Integrin: Critical Path to Antiangiogenic Therapy Resistance and Beyond. Cancer Res. 2014 Jan 1; 74(1):3-7.
    View on PubMed
  3. Ayodele MO, Pekmezci M, Aghi MK, Scott BJ. Headache and focal neurologic deficits in a 37-year-old woman. JAMA Neurol. 2013 Nov 1; 70(11):1445-9.
    View on PubMed
  4. Jahangiri A, Wagner J, Tran MT, Miller LM, Tom MW, Kunwar S, Blevins L, Aghi MK. Factors predicting postoperative hyponatremia and efficacy of hyponatremia management strategies after more than 1000 pituitary operations. J Neurosurg. 2013 Dec; 119(6):1478-83.
    View on PubMed
  5. Jahangiri A, Clark AJ, Han SJ, Kunwar S, Blevins LS, Aghi MK. Socioeconomic factors associated with pituitary apoplexy. J Neurosurg. 2013 Dec; 119(6):1432-6.
    View on PubMed
  6. Jahangiri A, Wagner JR, Pekmezci M, Hiniker A, Chang EF, Kunwar S, Blevins L, Aghi MK. A comprehensive long-term retrospective analysis of silent corticotrophic adenomas vs hormone-negative adenomas. Neurosurgery. 2013 Jul; 73(1):8-17; discussion 17-8.
    View on PubMed
  7. Bloch O, Safaee M, Sun MZ, Butowski NA, McDermott MW, Berger MS, Aghi MK, Parsa AT. Disseminated progression of glioblastoma after treatment with bevacizumab. Clin Neurol Neurosurg. 2013 Sep; 115(9):1795-801.
    View on PubMed
  8. Carbonell WS, DeLay M, Jahangiri A, Park CC, Aghi MK. ß1 integrin targeting potentiates antiangiogenic therapy and inhibits the growth of bevacizumab-resistant glioblastoma. Cancer Res. 2013 May 15; 73(10):3145-54.
    View on PubMed
  9. Hiniker A, Hagenkord JM, Powers MP, Aghi MK, Prados MD, Perry A. Gliosarcoma arising from an oligodendroglioma (oligosarcoma). Clin Neuropathol. 2013 May-Jun; 32(3):165-70.
    View on PubMed
  10. Ameri K, Rajah AM, Nguyen V, Sanders TA, Jahangiri A, Delay M, Donne M, Choi HJ, Tormos KV, Yeghiazarians Y, Jeffrey SS, Rinaudo PF, Rowitch DH, Aghi M, Maltepe E. Nuclear localization of the mitochondrial factor HIGD1A during metabolic stress. PLoS One. 2013; 8(4):e62758.
    View on PubMed
  11. Clark AJ, Jahangiri A, Garcia RM, George JR, Sughrue ME, McDermott MW, El-Sayed IH, Aghi MK. Endoscopic surgery for tuberculum sellae meningiomas: a systematic review and meta-analysis. Neurosurg Rev. 2013 Jul; 36(3):349-59.
    View on PubMed
  12. Safaee M, Clark AJ, Bloch O, Oh MC, Singh A, Auguste KI, Gupta N, McDermott MW, Aghi MK, Berger MS, Parsa AT. Surgical outcomes in choroid plexus papillomas: an institutional experience. J Neurooncol. 2013 May; 113(1):117-25.
    View on PubMed
  13. Jahangiri A, De Lay M, Miller LM, Carbonell WS, Hu YL, Lu K, Tom MW, Paquette J, Tokuyasu TA, Tsao S, Marshall R, Perry A, Bjorgan KM, Chaumeil MM, Ronen SM, Bergers G, Aghi MK. Gene expression profile identifies tyrosine kinase c-Met as a targetable mediator of antiangiogenic therapy resistance. Clin Cancer Res. 2013 Apr 1; 19(7):1773-83.
    View on PubMed
  14. Kaur G, Kane AJ, Sughrue ME, Madden M, Oh MC, Sun MZ, Safaee M, El-Sayed I, Aghi M, McDermott MW, Berger MS, Parsa AT. The prognostic implications of Hyam's subtype for patients with Kadish stage C esthesioneuroblastoma. J Clin Neurosci. 2013 Feb; 20(2):281-6.
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  15. Xi Y, Wei Y, Sennino B, Ulsamer A, Kwan I, Brumwell AN, Tan K, Aghi MK, McDonald DM, Jablons DM, Chapman HA. Identification of pY654-ß-catenin as a critical co-factor in hypoxia-inducible factor-1a signaling and tumor responses to hypoxia. Oncogene. 2013 Oct 17; 32(42):5048-57.
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  16. Jahangiri A, Jian B, Miller L, El-Sayed IH, Aghi MK. Skull base chordomas: clinical features, prognostic factors, and therapeutics. Neurosurg Clin N Am. 2013 Jan; 24(1):79-88.
    View on PubMed
  17. Bloch O, Han SJ, Cha S, Sun MZ, Aghi MK, McDermott MW, Berger MS, Parsa AT. Impact of extent of resection for recurrent glioblastoma on overall survival: clinical article. J Neurosurg. 2012 Dec; 117(6):1032-8.
    View on PubMed
  18. Ivan ME, Jahangiri A, El-Sayed IH, Aghi MK. Minimally invasive approaches to the anterior skull base. Neurosurg Clin N Am. 2013 Jan; 24(1):19-37.
    View on PubMed
  19. Hu YL, Jahangiri A, Delay M, Aghi MK. Tumor cell autophagy as an adaptive response mediating resistance to treatments such as antiangiogenic therapy. Cancer Res. 2012 Sep 1; 72(17):4294-9.
    View on PubMed
  20. Oh MC, Tihan T, Kunwar S, Blevins L, Aghi MK. Clinical management of pituitary carcinomas. Neurosurg Clin N Am. 2012 Oct; 23(4):595-606.
    View on PubMed

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