University of California San Francisco
Helen Diller Family Comprehensive Cancer Center
Spencer Behr, MD

Spencer Behr, MD

Co-Director, Cancer Imaging Research Shared Resource, UCSF Helen Diller Family Comprehensive Cancer Center; Assistant Professor of Radiology, UCSF

Research Summary

Spencer Behr, MD, is an Assistant Professor of Clinical Radiology and the Director of the Fellowship for both the Abdominal Imaging subspecialty and for the Department of Radiology and Biomedical Imaging at the University of California, San Francisco. He obtained his medical degree from Tufts University School of Medicine, Boston in 2005. In 2010, he completed a four-year Diagnostic Radiology residency at the Lahey Clinic Medical Center in Burlington, Massachusetts, followed by a fellowship in Abdominal Imaging and Nuclear Medicine at UCSF.

Dr. Behr has subspecialty training in abdominal imaging and nuclear medicine, and his research interests are focused on molecular and hybrid imaging translational research. He has selectively pursued interdepartmental projects to foster cross-disciplinary discussions and optimize the clinical impact of these projects.

Projects include: FDG PET in breast cancer, comparing breast cancer molecular subtypes with their respective FDG PET and breast MRI findings, CT findings in Celiac Disease, fluoro-18-fluorothymidine (FLT) PET as a potential marker of early response in patients with metastatic melanoma, CT appearance of malabsorption, and clinical applications of iodine-124 PET/CT in thyroid cancer.

Selected Publications

  1. Behr SC, Aggarwal R, Van Brocklin HF, Flavell RR, Geo K, Small EJ, Blecha J, Jivan S, Hope TA, Simko JP, Kurhanewicz J, Noworolski SM, Korn NJ, De Los Santos R, Cooperberg MR, Carroll PR, Nguyen HG, Greene KL, Langton-Webster B, Berkman CE, Seo Y. First-in-Human Phase I study of CTT1057, a Novel 18F Labeled Imaging Agent with Phosphoramidate Core Targeting Prostate Specific Membrane Antigen in Prostate Cancer. J Nucl Med. 2018 Nov 21.
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  2. Ding Y, Sohn JH, Kawczynski MG, Trivedi H, Harnish R, Jenkins NW, Lituiev D, Copeland TP, Aboian MS, Mari Aparici C, Behr SC, Flavell RR, Huang SY, Zalocusky KA, Nardo L, Seo Y, Hawkins RA, Hernandez Pampaloni M, Hadley D, Franc BL. A Deep Learning Model to Predict a Diagnosis of Alzheimer Disease by Using 18F-FDG PET of the Brain. Radiology. 2018 Nov 06; 180958.
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  3. Perez PM, Hope TA, Behr SC, van Zante A, Small EJ, Flavell RR. Intertumoral Heterogeneity of 18F-FDG and 68Ga-PSMA Uptake in Prostate Cancer Pulmonary Metastases. Clin Nucl Med. 2018 Nov 03.
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  4. Behr SC, Villanueva-Meyer JE, Li Y, Wang YH, Wei J, Moroz A, Lee JK, Hsiao JC, Gao KT, Ma W, Cha S, Wilson DM, Seo Y, Nelson SJ, Chang SM, Evans MJ. Targeting iron metabolism in high-grade glioma with 68Ga-citrate PET/MR. JCI Insight. 2018 Nov 02; 3(21).
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  5. Sherman CB, Behr S, Dodge JL, Roberts JP, Yao FY, Mehta N. Distinguishing Tumor from Bland Portal Vein Thrombus in Liver Transplant Candidates with Hepatocellular Carcinoma: The "A-VENA" Criteria. Liver Transpl. 2018 Sep 24.
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  6. Huang SY, Franc BL, Harnish RJ, Liu G, Mitra D, Copeland TP, Arasu VA, Kornak J, Jones EF, Behr SC, Hylton NM, Price ER, Esserman L, Seo Y. Exploration of PET and MRI radiomic features for decoding breast cancer phenotypes and prognosis. NPJ Breast Cancer. 2018; 4:24.
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  7. Wang ZJ, Behr S, Consunji MV, Yeh BM, Ohliger MA, Gao K, Ko AH, Cinar P, Tempero MA, Collisson EA. Early Response Assessment in Pancreatic Ductal Adenocarcinoma Through Integrated PET/MRI. AJR Am J Roentgenol. 2018 Jul 31; 1-10.
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  8. Jha P, Behr S, Morgan T, Washburn E, Lucero J, Chen LM, Poder L. Imaging findings of concealed intra-amniotic hemorrhage in the setting of placenta previa and placenta accreta spectrum disorder. Emerg Radiol. 2018 Jun 17.
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  9. Jordan CD, Han M, Kondapavulur S, Vera DB, Neumann KD, Moore T, Stillson C, Krug R, Behr S, Seo Y, VanBrocklin HF, Larson PEZ, Wilson M, Martin AJ, Hetts SW. Quantification of 89 Zr-Iron oxide nanoparticle biodistribution using PET-MR and ultrashort TE sequences. J Magn Reson Imaging. 2018 May 14.
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  10. Calabrese E, Baghdanian AH, Zagoria RJ, Behr SC. Arteriovenous malformation of the ureter diagnosed by CT urogram. Urol Case Rep. 2018 Jul; 19:20-22.
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  11. Lim HC, Montesion M, Botton T, Collisson EA, Umetsu SE, Behr SC, Gordan JD, Stephens PJ, Kelley RK. Hybrid Capture-Based Tumor Sequencing and Copy Number Analysis to Confirm Origin of Metachronous Metastases in BRCA1-Mutant Cholangiocarcinoma Harboring a Novel YWHAZ-BRAF Fusion. Oncologist. 2018 Apr 05.
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  12. Marcus SG, Candia S, Kohli MD, Mongan J, Zagoria RJ, Behr SC, Sun D, Westphalen AC. Association between misty mesentery with baseline or new diagnosis of cancer: a matched cohort study. Clin Imaging. 2017 Dec 15; 50:57-61.
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  13. Behr SC, Bahroos E, Hawkins RA, Nardo L, Ravanfar V, Capbarat EV, Seo Y. Quantitative and Visual Assessments toward Potential Sub-mSv or Ultrafast FDG PET Using High-Sensitivity TOF PET in PET/MRI. Mol Imaging Biol. 2017 Nov 30.
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  14. Cabarrus MC, Yeh BM, Phelps AS, Ou JJ, Behr SC. From Inguinal Hernias to Spermatic Cord Lipomas: Pearls, Pitfalls, and Mimics of Abdominal and Pelvic Hernias. Radiographics. 2017 Nov-Dec; 37(7):2063-2082.
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  15. Fernandez A, Conrad M, Gill RM, Choi WT, Kumar V, Behr S. Solitary fibrous tumor in the abdomen and pelvis: A case series with radiological findings and treatment recommendations. Clin Imaging. 2018 Mar - Apr; 48:48-54.
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  16. Garcia-Reyes K, Nguyen HG, Zagoria RJ, Shinohara K, Carroll PR, Behr SC, Westphalen AC. Impact of Lesion Visibility on Transrectal Ultrasound on the Prediction of Clinically Significant Prostate Cancer (Gleason Score 3 + 4 or Greater) with Transrectal Ultrasound-Magnetic Resonance Imaging Fusion Biopsy. J Urol. 2017 Sep 20.
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  17. Lake ST, Greene KL, Westphalen AC, Behr SC, Zagoria R, Small EJ, Carroll PR, Hope TA. Optimal MRI sequences for 68Ga-PSMA-11 PET/MRI in evaluation of biochemically recurrent prostate cancer. EJNMMI Res. 2017 Sep 19; 7(1):77.
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  18. Leapman MS, Wang ZJ, Behr SC, Kurhanewicz J, Zagoria RJ, Carroll PR, Westphalen AC. Impact of the integration of proton magnetic resonance imaging spectroscopy to PI-RADS 2 for prediction of high grade and high stage prostate cancer. Radiol Bras. 2017 Sep-Oct; 50(5):299-307.
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  19. Katz MHG, Ou FS, Herman JM, Ahmad SA, Wolpin B, Marsh R, Behr S, Shi Q, Chuong M, Schwartz LH, Frankel W, Collisson E, Koay EJ, Hubbard JM, Leenstra JL, Meyerhardt J, O'Reilly E. Alliance for clinical trials in oncology (ALLIANCE) trial A021501: preoperative extended chemotherapy vs. chemotherapy plus hypofractionated radiation therapy for borderline resectable adenocarcinoma of the head of the pancreas. BMC Cancer. 2017 Jul 27; 17(1):505.
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  20. Aggarwal R, Behr SC, Paris PL, Truillet C, Parker MFL, Huynh LT, Wei J, Hann B, Youngren J, Huang J, Premasekharan G, Ranatunga N, Chang E, Gao KT, Ryan CJ, Small EJ, Evans MJ. Real-Time Transferrin-Based PET Detects MYC-Positive Prostate Cancer. Mol Cancer Res. 2017 Sep; 15(9):1221-1229.
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