University of California San Francisco
Helen Diller Family Comprehensive Cancer Center
Steve E. Braunstein, MD, PhD

Steve E. Braunstein, MD, PhD

Assistant Professor, Associate Program Director, Dept. of Radiation Oncology, UCSF

Cancer Center Program Memberships

Neurologic Oncology

Research Summary

Dr. Braunstein is a radiation oncologist with a clinical interest in the treatment of pediatric, central nervous system, and soft tissue malignancies. He has expertise in modern radiation therapy techniques including stereotactic radiotherapy (Gamma Knife, Cyberknife, Linac-based SBRT), intraoperative radiotherapy, and intensity modulated radiation therapy.

Dr. Braunstein earned his M.D. at New York University School of Medicine where he also obtained a Ph.D. studying essential molecular pathways by which cancer cells mediate response to radiation. He completed residency at UCSF in 2014, during which time he continued to study cancer cell response to radiation, investigating genetic polymorphisms which yield the observed heterogeneity of tumor cell population radiosensitivity and risk of radiation-related secondary cancer.

Education

University of California, San Francisco, 06/14, Radiation Oncology
Brighman and Women's Hospital, 06/10, Internal Medicine
New York University School of Medicine, M.D., Ph.D., 06/09


Professional Experience

  • 2014-present
    Assistant Professor, Radiation Oncology, UCSF
  • 2010-2014
    Resident, Radiation Oncology, UCSF
  • 2015-present
    Associate Program Director, Department of Radiation Oncology, UCSF

Honors & Awards

  • 2014
    RSNA Resident Research Award, Radiological Society of North America
  • 2014
    UCSF Patient Care Fund Award, UCSF
  • 2014
    Mount Zion Fund Research Travel Award, UCSF
  • 2013
    UCSF Exceptional Physician Award, UCSF
  • 2013
    UCSF Resident QI Champion, UCSF
  • 2012
    UCSF Patient Care Fund Award, UCSF
  • 2008
    AOA Inductee, NYUSOM
  • 2008
    Honors in Doctoral Dissertation, NYUSOM
  • 2003
    NYC Urban Health Initiative Award, NYC Department of Public Health

Selected Publications

  1. Chen WC, Magill ST, Wu A, Vasudevan HN, Morin O, Aghi MK, Theodosopoulos PV, Perry A, McDermott MW, Sneed PK, Braunstein SE, Raleigh DR. Histopathological features predictive of local control of atypical meningioma after surgery and adjuvant radiotherapy. J Neurosurg. 2018 Apr 06; 1-8.
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  2. Vasudevan HN, Braunstein SE, Phillips JJ, Pekmezci M, Tomlin BA, Wu A, Reis GF, Magill ST, Zhang J, Feng FY, Nicholaides T, Chang SM, Sneed PK, McDermott MW, Berger MS, Perry A, Raleigh DR. Comprehensive Molecular Profiling Identifies FOXM1 as a Key Transcription Factor for Meningioma Proliferation. Cell Rep. 2018 Mar 27; 22(13):3672-3683.
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  3. Weinberg BD, Boreta L, Braunstein S, Cha S. Location of subventricular zone recurrence and its radiation dose predicts survival in patients with glioblastoma. J Neurooncol. 2018 Mar 15.
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  4. Chen WC, Hara J, Magill ST, Wu A, Aghi MK, Theodosopoulos PV, Perry A, McDermott MW, Sneed PK, Raleigh DR, Braunstein SE. Salvage therapy outcomes for atypical meningioma. J Neurooncol. 2018 Feb 26.
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  5. McTyre E, Ayala-Peacock D, Contessa J, Corso C, Chiang V, Chung C, Fiveash J, Ahluwalia M, Kotecha R, Chao S, Attia A, Henson A, Hepel J, Braunstein S, Chan M. Multi-institutional competing risks analysis of distant brain failure and salvage patterns after upfront radiosurgery without whole brain radiotherapy for brain metastasis. Ann Oncol. 2018 Feb 01; 29(2):497-503.
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  6. Krauze AV, Attia A, Braunstein S, Chan M, Combs SE, Fietkau R, Fiveash J, Flickinger J, Grosu A, Howard S, Nieder C, Niyazi M, Rowe L, Smart DD, Tsien C, Camphausen K. Correction to expert consensus on re-irradiation for recurrent glioma. Radiat Oncol. 2018 01 18; 13(1):8.
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  7. Han DY, Ma L, Braunstein S, Raleigh D, Sneed PK, McDermott M. Resection Cavity Contraction Effects in the Use of Radioactive Sources (1-25 versus Cs-131) for Intra-Operative Brain Implants. Cureus. 2018 Jan 16; 10(1):e2079.
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  8. Xu MJ, Su D, Deboer R, Garcia M, Tahir P, Anderson W, Kinderman A, Braunstein S, Sherertz T. Palliative Oncologic Care Curricula for Providers in Resource-Limited and Underserved Communities: a Systematic Review. J Cancer Educ. 2017 Dec 20.
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  9. Wu A, Garcia MA, Magill ST, Chen W, Vasudevan HN, Perry A, Theodosopoulos PV, McDermott MW, Braunstein SE, Raleigh DR. Presenting Symptoms and Prognostic Factors for Symptomatic Outcomes Following Resection of Meningioma. World Neurosurg. 2018 Mar; 111:e149-e159.
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  10. Krauze AV, Attia A, Braunstein S, Chan M, Combs SE, Fietkau R, Fiveash J, Flickinger J, Grosu A, Howard S, Nieder C, Niyazi M, Rowe L, Smart DD, Tsien C, Camphausen K. Expert consensus on re-irradiation for recurrent glioma. Radiat Oncol. 2017 Dec 01; 12(1):194.
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  11. Sperduto PW, Jiang W, Brown PD, Braunstein S, Sneed P, Wattson DA, Shih HA, Bangdiwala A, Shanley R, Lockney NA, Beal K, Lou E, Amatruda T, Sperduto WA, Kirkpatrick JP, Yeh N, Gaspar LE, Molitoris JK, Masucci L, Roberge D, Yu J, Chiang V, Mehta M. Estimating Survival in Melanoma Patients With Brain Metastases: An Update of the Graded Prognostic Assessment for Melanoma Using Molecular Markers (Melanoma-molGPA). Int J Radiat Oncol Biol Phys. 2017 11 15; 99(4):812-816.
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  12. Ayala-Peacock DN, Attia A, Braunstein SE, Ahluwalia MS, Hepel J, Chung C, Contessa J, McTyre E, Peiffer AM, Lucas JT, Isom S, Pajewski NM, Kotecha R, Stavas MJ, Page BR, Kleinberg L, Shen C, Taylor RB, Onyeuku NE, Hyde AT, Gorovets D, Chao ST, Corso C, Ruiz J, Watabe K, Tatter SB, Zadeh G, Chiang VLS, Fiveash JB, Chan MD. Prediction of new brain metastases after radiosurgery: validation and analysis of performance of a multi-institutional nomogram. J Neurooncol. 2017 Nov; 135(2):403-411.
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  13. Neeley BC, Golden DW, Brower JV, Braunstein SE, Hirsch AE, Mattes MD. Student Perspectives on Oncology Curricula at United States Medical Schools. J Cancer Educ. 2017 Aug 07.
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  14. Paulsson AK, Braunstein S, Phillips J, Theodosopoulos PV, McDermott M, Sneed PK, Ma L. Patient-Specific Fetal Dose Determination for Multi-Target Gamma Knife Radiosurgery: Computational Model and Case Report. Cureus. 2017 Jul 31; 9(7):e1527.
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  15. Vasudevan HN, Raleigh DR, Johnson J, Garsa AA, Theodosopoulos PV, Aghi MK, Ames C, McDermott MW, Barani IJ, Braunstein SE. Management of Chordoma and Chondrosarcoma with Fractionated Stereotactic Radiotherapy. Front Surg. 2017; 4:35.
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  16. Sperduto PW, Yang TJ, Beal K, Pan H, Brown PD, Bangdiwala A, Shanley R, Yeh N, Gaspar LE, Braunstein S, Sneed P, Boyle J, Kirkpatrick JP, Mak KS, Shih HA, Engelman A, Roberge D, Arvold ND, Alexander B, Awad MM, Contessa J, Chiang V, Hardie J, Ma D, Lou E, Sperduto W, Mehta MP. Estimating Survival in Patients With Lung Cancer and Brain Metastases: An Update of the Graded Prognostic Assessment for Lung Cancer Using Molecular Markers (Lung-molGPA). JAMA Oncol. 2017 Jun 01; 3(6):827-831.
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  17. Kline CN, Joseph NM, Grenert JP, van Ziffle J, Talevich E, Onodera C, Aboian M, Cha S, Raleigh DR, Braunstein S, Torkildson J, Samuel D, Bloomer M, Campomanes AGA, Banerjee A, Butowski N, Raffel C, Tihan T, Bollen AW, Phillips JJ, Korn WM, Yeh I, Bastian BC, Gupta N, Mueller S, Perry A, Nicolaides T, Solomon DA. Targeted next-generation sequencing of pediatric neuro-oncology patients improves diagnosis, identifies pathogenic germline mutations, and directs targeted therapy. Neuro Oncol. 2017 05 01; 19(5):699-709.
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  18. Braunstein S, Raleigh D, Bindra R, Mueller S, Haas-Kogan D. Pediatric high-grade glioma: current molecular landscape and therapeutic approaches. J Neurooncol. 2017 Sep; 134(3):541-549.
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  19. Sperduto PW, Jiang W, Brown PD, Braunstein S, Sneed P, Wattson DA, Shih HA, Bangdiwala A, Shanley R, Lockney NA, Beal K, Lou E, Amatruda T, Sperduto WA, Kirkpatrick JP, Yeh N, Gaspar LE, Molitoris JK, Masucci L, Roberge D, Yu J, Chiang V, Mehta M. The Prognostic Value of BRAF, C-KIT, and NRAS Mutations in Melanoma Patients With Brain Metastases. Int J Radiat Oncol Biol Phys. 2017 08 01; 98(5):1069-1077.
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  20. Magnuson WJ, Lester-Coll NH, Wu AJ, Yang TJ, Lockney NA, Gerber NK, Beal K, Amini A, Patil T, Kavanagh BD, Camidge DR, Braunstein SE, Boreta LC, Balasubramanian SK, Ahluwalia MS, Rana NG, Attia A, Gettinger SN, Contessa JN, Yu JB, Chiang VL. Management of Brain Metastases in Tyrosine Kinase Inhibitor-Naïve Epidermal Growth Factor Receptor-Mutant Non-Small-Cell Lung Cancer: A Retrospective Multi-Institutional Analysis. J Clin Oncol. 2017 Apr 01; 35(10):1070-1077.
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