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Sophie Dumont, PhD

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
dumont_sophie

Assistant Professor, Dept of Cell & Tissue Biology, Dept of Cellular & Molecular Pharmacology, University of California, San Francisco


Additional Websites


Education

Princeton University, Princeton, NJ, USA, B.A., 08/95-06/99, Physics
University of Oxford, UK, D.Phil. candidate, 09/99-08/00, Theoretical Physics
University of California, Berkeley, CA, USA, Ph.D., 08/00-12/05, Molecular Biophysics
University of California, Berkeley, CA, USA, Postdoc, 01/06-03/06, Molecular Biophysics
Harvard Society of Fellows, Junior Fellow, 07/06-06/09, Cellular Biophysics
Harvard Medical School, Boston, MA, USA, Postdoc, 07/06-05/12, Cellular Biophysics
 


Professional Experience

  • 1997-1999
    Undergraduate Student Researcher, Princeton University, Advisor: Prof. Stanislas Leibler (Physics), Thesis: Thermal sensing network of E. coli
  • 1999-2000
    Graduate Student Researcher, University of Oxford, Advisor: Prof. Douglas Abraham (Theoretical Physics), Topic: Statistical mechanics of neural networks
  • 2000-2005
    Graduate Student Researcher, University of California, Berkeley, Advisor: Prof. Carlos Bustamante (Physics), Thesis: Force and helicase-catalyzed mechanical unfolding of single RNA molecules
  • 2006
    Postdoctoral fellow, University of California, Berkeley, Advisors: Prof. Carlos Bustamante (Physics), Prof. Ignacio Tinoco Jr. (Chemistry), Topic: Helicase mechanochemistry
  • 2006-2009
    Junior Fellow, Harvard Society of Fellows, Mentor: Prof. Timothy J. Mitchison (Systems Biology), Topic: Mechanical forces in cell division
  • 2006-2012
    Postdoctoral Fellow, Harvard Medical School, Mentor: Prof. Timothy J. Mitchison (Systems Biology), Topic: Mechanical forces in cell division
  • 2012-
    Assistant Professor, University of California, San Francisco, Dept of Cell & Tissue Biology, Dept of Cellular & Molecular Pharmacology

Honors & Awards

  • 1999
    Phi Beta Kappa; Sigma Xi
  • 1999
    Allen G. Shenstone Prize in Physics, Princeton University
  • 1999-2000
    Rhodes Scholarship
  • 1999-2001
    Québec Fund for Nature and Technology Research Fellowship (masters)
  • 2001-2003
    Natural Sciences and Engineering Council of Canada Fellowship (doctoral)
  • 2001-2004
    Québec Fund for Nature and Technology Research Fellowship (doctoral)
  • 2004
    Outstanding Graduate Student Instructor Award, UC Berkeley
  • 2004
    Teaching Effectiveness Graduate Student Instructor Award, UC Berkeley
  • 2004-2005
    Canadian Institutes of Health Research Fellowship (doctoral)
  • 2006
    Alan Bearden Outstanding Graduate Research Award, UC Berkeley
  • 2006
    Weintraub Graduate Student Award
  • 2006-2009
    Junior Fellow, Harvard Society of Fellows
  • 2007-2009
    Harvard University William F. Milton Fund Award
  • 2009-2011
    Charles A. King Trust Postdoctoral Fellowship
  • 2010-2015
    NIH K99/R00 Pathway to Independence Award
  • 2013-2015
    Sloan Research Fellow
  • 2013-2015
    Kimmel Cancer Foundation Scholar
  • 2013-2016
    Searle Scholar
  • 2013-2018
    Rita Allen Foundation and Milton E. Cassel Scholar

Selected Publications

  1. Dumont S. Spindle size: small droplets and a big step forward. Curr Biol. 2014 Feb 3; 24(3):R116-8.
    View on PubMed
  2. Kuhn J, Dumont S. Methods in Cell Biology. Imaging and physically probing kinetochores in live dividing cells. 2014; in press.
    View on PubMed
  3. Dumont S, Salmon ED, Mitchison TJ. Deformations within moving kinetochores reveal different sites of active and passive force generation. Science. 2012 Jul 20; 337(6092):355-8.
    View on PubMed
  4. Dumont S, Mitchison TJ. Comprehensive Biophysics. Mechanical Forces in Mitosis. 2012; 298-320.
    View on PubMed
  5. Dumont S. Chromosome segregation: spindle mechanics come to life. Curr Biol. 2011 Sep 27; 21(18):R688-90.
    View on PubMed
  6. Dumont S, Mitchison TJ. Force and length in the mitotic spindle. Curr Biol. 2009 Sep 15; 19(17):R749-61.
    View on PubMed
  7. Dumont S, Mitchison TJ. Compression regulates mitotic spindle length by a mechanochemical switch at the poles. Curr Biol. 2009 Jul 14; 19(13):1086-95.
    View on PubMed
  8. Wühr M, Dumont S, Groen AC, Needleman DJ, Mitchison TJ. How does a millimeter-sized cell find its center? Cell Cycle. 2009 Apr 15; 8(8):1115-21.
    View on PubMed
  9. Wühr M, Chen Y, Dumont S, Groen AC, Needleman DJ, Salic A, Mitchison TJ. Evidence for an upper limit to mitotic spindle length. Curr Biol. 2008 Aug 26; 18(16):1256-61.
    View on PubMed
  10. Cheng W, Dumont S, Tinoco I, Bustamante C. NS3 helicase actively separates RNA strands and senses sequence barriers ahead of the opening fork. Proc Natl Acad Sci U S A. 2007 Aug 28; 104(35):13954-9.
    View on PubMed
  11. Dumont S, Cheng W, Serebrov V, Beran RK, Tinoco I, Pyle AM, Bustamante C. RNA translocation and unwinding mechanism of HCV NS3 helicase and its coordination by ATP. Nature. 2006 Jan 5; 439(7072):105-8.
    View on PubMed
  12. Onoa B, Dumont S, Liphardt J, Smith SB, Tinoco I, Bustamante C. Identifying kinetic barriers to mechanical unfolding of the T. thermophila ribozyme. Science. 2003 Mar 21; 299(5614):1892-5.
    View on PubMed
  13. Liphardt J, Dumont S, Smith SB, Tinoco I, Bustamante C. Equilibrium information from nonequilibrium measurements in an experimental test of Jarzynski's equality. Science. 2002 Jun 7; 296(5574):1832-5.
    View on PubMed

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