University of California San Francisco
Helen Diller Family Comprehensive Cancer Center
Mary Feng, MD

Mary Feng, MD

Associate Professor of Clinical Radiation Oncology, UCSF

Cancer Center Program Memberships

Experimental Therapeutics

Research Summary

Dr. Mary Feng specialized in treatment of gastrointestinal and hepatobiliary cancers. Her research focuses on technical and biological methods to individualize and adapt radiotherapy for each patient with pancreas and liver cancer to maximize the effectiveness of treatment. Her primary goals are 1) Improving outcomes for patients with pancreas and liver cancer through novel combination treatments; 2) Adapting radiotherapy based on early blood and imaging biomarkers of tumor response and treatment effects on nearby organs; and 3) Evaluating the use of advanced technologies in radiotherapy.

Dr. Feng is Vice-Chair for Clinical Research, Clinical site director for the Mission Bay Clinic, and Director of Quality Assurance and Safety for the Department of Radiation Oncology at UCSF. She also serves on numerous national and international cancer organization panels and groups, including the National Comprehensive Cancer Network Pancreatic Adenocarcinoma Panel, the American Society of Clinical Oncology Gastrointestinal Cancer Guideline Advisory Group, and the American Society for Radiation Oncology IHE-RO Clinical Advisory Subcommittee as co-chair.

Education

Stanford University, Stanford, CA, BS with Honors, 06/1997, Biological Sciences
Washington University School of Medicine, MD, 05/2002
University of Michigan Medical Center, Intern, 06/2003, Preliminary Medical
University of Michigan Medical Center, Resident, 06/2006, Radiation Oncology
University of Michigan Medical Center, Chief Resident, 06/2007, Radiation Oncology

Professional Experience

  • 2007-2009
    Clinical Instructor, Radiation Oncology, University of Michigan
  • 2009-2013
    Clinical Assistant Professor, Radiation Oncology, University of Michigan
  • 2011-2016
    Medical Director, MRI Program, Radiation Oncology, University of Michigan
  • 2012-2016
    Associate Director of Clinical Research, Radiation Oncology, University of Michigan
  • 2013-2016
    Clinical Associate Professor, Radiation Oncology, University of Michigan
  • 2016-present
    Associate Professor, Radiation Oncology, UCSF
  • 2016-present
    Vice Chair for Clinical Research, Radiation Oncology, UCSF
  • 2016-present
    Director of Mission Bay Clinic, Radiation Oncology, UCSF
  • 2016-present
    Director of Quality Assurance and Safety, Radiation Oncology, UCSF

Honors & Awards

  • 1996
    Howard Hughes Medical Institute Summer Research Fellowship, Stanford University
  • 1998
    American Red Cross Volunteer of the Year, Palo Alto, CA chapter
  • 1998
    Philpott Scholarship, Washington University School of Medicine
  • 1999
    Howard Hughes Medical Institute Summer Radiation Oncology Fellowship, Mallinckrodt Institute
  • 2005
    Member-in-Training Award for Outstanding RSNA Presentation in Radiation Oncology, American Association for Women Radiologists
  • 2006
    Member-in-Training Award for Outstanding ASTRO Presentation in Radiation Oncology, American Association for Women Radiologists
  • 2007
    Resident Research and Education Foundation Award, RSNA
  • 2007
    ASTRO plenary session presentation

Selected Publications

  1. Pollom EL, Lee K, Durkee BY, Grade M, Mokhtari DA, Wahl DR, Feng M, Kothary N, Koong AC, Owens DK, Goldhaber-Fiebert J, Chang DT. Cost-effectiveness of Stereotactic Body Radiation Therapy versus Radiofrequency Ablation for Hepatocellular Carcinoma: A Markov Modeling Study. Radiology. 2017 May; 283(2):460-468.
    View on PubMed
  2. Moran JM, Feng M, Benedetti LA, Marsh R, Griffith KA, Matuszak MM, Hess M, McMullen M, Fisher JH, Nurushev T, Grubb M, Gardner S, Nielsen D, Jagsi R, Hayman JA, Pierce LJ. Development of a model web-based system to support a statewide quality consortium in radiation oncology. Pract Radiat Oncol. 2017 May - Jun; 7(3):e205-e213.
    View on PubMed
  3. Wu VW, Epelman MA, Wang H, Edwin Romeijn H, Feng M, Cao Y, Ten Haken RK, Matuszak MM. Optimizing global liver function in radiation therapy treatment planning. Phys Med Biol. 2016 Sep 07; 61(17):6465-84.
    View on PubMed
  4. Wahl DR, Tao Y, Schipper M, Lawrence TS, Feng M. Reply to Yang et al and De Bari et al. J Clin Oncol. 2016 Aug 10; 34(23):2799.
    View on PubMed
  5. Sapir E, Tao Y, Feng F, Samuels S, El Naqa I, Murdoch-Kinch CA, Feng M, Schipper M, Eisbruch A. Predictors of Dysgeusia in Patients With Oropharyngeal Cancer Treated With Chemotherapy and Intensity Modulated Radiation Therapy. Int J Radiat Oncol Biol Phys. 2016 Oct 01; 96(2):354-361.
    View on PubMed
  6. Younge KC, Lee C, Moran JM, Feng M, Novelli P, Prisciandaro JI. Failure mode and effects analysis in a dual-product microsphere brachytherapy environment. Pract Radiat Oncol. 2016 Nov - Dec; 6(6):e299-e306.
    View on PubMed
  7. Shilkrut M, Sapir E, Hanasoge S, Schipper MJ, Normolle DP, Ben-Josef E, Ensminger W, Lawrence TS, Feng M. Phase I Trial of Dose-escalated Whole Liver Irradiation With Hepatic Arterial Fluorodeoxyuridine/Leucovorin and Streptozotocin Followed by Fluorodeoxyuridine/Leucovorin and Chemoembolization for Patients With Neuroendocrine Hepatic Metastases. Am J Clin Oncol. 2016 Feb 15.
    View on PubMed
  8. Matuszak MM, Hadley SW, Feng M, Hayman JA, Brock KK, Burger P, Owen D, Suresh K, Schipper M, Lawrence TS, Moran JM. Enhancing safety and quality through preplanning peer review for patients undergoing stereotactic body radiation therapy. Pract Radiat Oncol. 2016 Mar-Apr; 6(2):e39-46.
    View on PubMed
  9. Wahl DR, Stenmark MH, Tao Y, Pollom EL, Caoili EM, Lawrence TS, Schipper MJ, Feng M. Outcomes After Stereotactic Body Radiotherapy or Radiofrequency Ablation for Hepatocellular Carcinoma. J Clin Oncol. 2016 Feb 10; 34(5):452-9.
    View on PubMed
  10. Wang H, Feng M, Jackson A, Ten Haken RK, Lawrence TS, Cao Y. Local and Global Function Model of the Liver. Int J Radiat Oncol Biol Phys. 2016 Jan 01; 94(1):181-8.
    View on PubMed
  11. Jagsi R, Griffith KA, Boike TP, Walker E, Nurushev T, Grills IS, Moran JM, Feng M, Hayman J, Pierce LJ. Differences in the Acute Toxic Effects of Breast Radiotherapy by Fractionation Schedule: Comparative Analysis of Physician-Assessed and Patient-Reported Outcomes in a Large Multicenter Cohort. JAMA Oncol. 2015 Oct; 1(7):918-30.
    View on PubMed
  12. Paradis E, Cao Y, Lawrence TS, Tsien C, Feng M, Vineberg K, Balter JM. Assessing the Dosimetric Accuracy of Magnetic Resonance-Generated Synthetic CT Images for Focal Brain VMAT Radiation Therapy. Int J Radiat Oncol Biol Phys. 2015 Dec 01; 93(5):1154-61.
    View on PubMed
  13. Feng M, Brunner TB, Ben-Josef E. Stereotactic Body Radiation Therapy for Liver Cancer: Effective Therapy With Minimal Impact on Quality of Life. Int J Radiat Oncol Biol Phys. 2015 Sep 01; 93(1):26-8.
    View on PubMed
  14. Zhou J, Fang CX, Shen J, Schipper MJ, Zalupski MM, Minter RM, Simeone DM, Hart D, Eagle T, Kimmel GW, Vainshtein J, Lawrence TS, Feng M. Definitive Chemoradiation With Full-dose Gemcitabine for Unresectable Pancreatic Cancer: Efficacy of Involved-Field Radiotherapy. Am J Clin Oncol. 2015 Jul 09.
    View on PubMed
  15. Davis EJ, Chugh R, Zhao L, Lucas DR, Biermann JS, Zalupski MM, Feng M, Wong SL, Jacobson J, Zyczynski L, Reinke D, Metko G, Baker LH, Schuetze SM. A randomised, open-label, phase II study of neo/adjuvant doxorubicin and ifosfamide versus gemcitabine and docetaxel in patients with localised, high-risk, soft tissue sarcoma. Eur J Cancer. 2015 Sep; 51(13):1794-802.
    View on PubMed
  16. Hsu SH, Cao Y, Lawrence TS, Tsien C, Feng M, Grodzki DM, Balter JM. Quantitative characterizations of ultrashort echo (UTE) images for supporting air-bone separation in the head. Phys Med Biol. 2015 Apr 07; 60(7):2869-80.
    View on PubMed
  17. Shumway DA, Griffith KA, Pierce LJ, Feng M, Moran JM, Stenmark MH, Jagsi R, Hayman JA. Wide Variation in the Diffusion of a New Technology: Practice-Based Trends in Intensity-Modulated Radiation Therapy (IMRT) Use in the State of Michigan, With Implications for IMRT Use Nationally. J Oncol Pract. 2015 May; 11(3):e373-9.
    View on PubMed
  18. Siegel GW, Biermann JS, Chugh R, Jacobson JA, Lucas D, Feng M, Chang AC, Smith SR, Wong SL, Hasen J. The multidisciplinary management of bone and soft tissue sarcoma: an essential organizational framework. J Multidiscip Healthc. 2015; 8:109-15.
    View on PubMed
  19. Jagsi R, Griffith KA, Heimburger D, Walker EM, Grills IS, Boike T, Feng M, Moran JM, Hayman J, Pierce LJ. Choosing wisely? Patterns and correlates of the use of hypofractionated whole-breast radiation therapy in the state of Michigan. Int J Radiat Oncol Biol Phys. 2014 Dec 01; 90(5):1010-6.
    View on PubMed
  20. Cuneo KC, Chenevert TL, Ben-Josef E, Feng MU, Greenson JK, Hussain HK, Simeone DM, Schipper MJ, Anderson MA, Zalupski MM, Al-Hawary M, Galban CJ, Rehemtulla A, Feng FY, Lawrence TS, Ross BD. A pilot study of diffusion-weighted MRI in patients undergoing neoadjuvant chemoradiation for pancreatic cancer. Transl Oncol. 2014 Oct; 7(5):644-9.
    View on PubMed

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