Daphne A. Haas-Kogan, MD

Professor, Vice-Chair for Research, Department of Radiation Oncology, UCSF

Phone: (415) 353-9807 (appts)
Box 1708, UCSF
San Francisco, CA 94143-1708

View on UCSF Profiles

Additional Websites

• Physician Referral Directory

Education

Harvard University Cambridge, MA, A.B., 1986, Biochemical Sciences
University of California, San Francisco, M.D., 1991, Medicine
University of California, San Francisco, Postdoctorate, 1993, Radiation Oncology
University of California, San Francisco, Residency, 1997, Radiation Oncology

Professional Experience

• 1989-1990
  Research Fellow, Laboratory of Dr. J. Michael Bishop, G. W. Hooper Foundation, University of California, San Francisco, CA
• 1991-1992
  Medical Intern, California Pacific Medical Center, San Francisco, CA
• 1992-1994
  Postdoctoral Fellow, Laboratory of Dr. Mark Israel, Brain Tumor Research Institute, University of California, San Francisco, CA
• 1994-1997
  Resident, Department of Radiation Oncology, University of California, San Francisco, CA.
• 1996-1997
  Chief Resident, Department of Radiation Oncology, University of California, San Francisco, CA
• 1997-2003
  Assistant Professor, Dept. of Radiation Oncology, University of California, San Francisco, CA
• 2002-2011
  Associate Professor, Dept. of Radiation Oncology, University of California, San Francisco, CA
• 2003-present
  Vice-Chair for Research, Dept. of Radiation Oncology, University of California, San Francisco, CA
• 2011-present
  Professor, Dept. of Radiation Oncology, University of California, San Francisco, CA

Honors & Awards

• 1985
  Joseph L. Barrett Award for Teaching, Harvard University
• 1986
  Phi Beta Kappa, Harvard University
• 1986
  Thomas T. Hoopes Prize awarded to Senior Honors Thesis
• 1986
  Summa cum laude awarded to Senior Honors Thesis
• 1991
  Alpha Omega Alpha, University of California, San Francisco
• 1995
  ASTRO Basic Scientist Research Award
• 1995
  Junior Scientist Travel Award, 10th International Congress of Radiation Research
• 1995
  American Cancer Society Clinical Oncology Fellowship
• 1997
  Radiological Society of North America Scholar Award
• 1998
  UCSF Dean representative to Association of American Medical Colleges Professional Development Seminar for Junior Women Faculty, Santa Fe, New Mexico.
• 1999
  Pfizer Scholars Grant for New Faculty.
• 1999
  First place: CAP competition, General Clinical Research Center National Meeting; Arlington, VA.
• 1999
  UCSF-Mount Zion Clinical Investigator Award.
• 2000
  American Society of Clinical Oncology Career Development Award.
• 2002
  Henry J. Kaiser Award for Excellence in Teaching, UCSF School of Medicine.
• 2002
  UCSF Nominee, Assoc of American Medical Colleges (AAMC) Humanism in Medicine Award.
• 2003
  Nominated for Teaching Award, UCSF School of Medicine.
• 2004
  Nominee: Henry J. Kaiser Award for Excellence in Teaching, UCSF School of Medicine.
• 2005
  Selected one of Best San Francisco Doctors for San Francisco Magazine, January 2005.
• 2006
  Alpha Omega Alpha, nominated by Medical Student Class of 2007 for AOA membership in the alumni category at the University of California, San Francisco.
• 2009-2010
  Mentor: Howard Hughes Medical Institute Research Training Fellowship for Medical Students.
• 2007-2011
  Best Doctors in America®

Selected Publications

1. Mueller S, Bhargava S, Molinaro AM, Yang X, Kolkowitz I, Olow A, Wehmeijer N, Orbach S, Chen J, Matthay KK, Haas-Kogan DA. Poly (ADP-Ribose) Polymerase Inhibitor MK-4827 together with Radiation as a Novel Therapy for Metastatic Neuroblastoma. Anticancer Res. 2013 Mar; 33(3):755-62.
   View on PubMed
2. Raleigh DR, Haas-Kogan DA. Molecular targets and mechanisms of radiosensitization using DNA damage response pathways. Future Oncol. 2013 Feb; 9(2):219-33.
   View on PubMed
3. Gajjar A, Packer RJ, Foreman NK, Cohen K, Haas-Kogan D, Merchant TE. Children's Oncology Group's 2013 blueprint for research: Central nervous system tumors. Pediatr Blood Cancer. 2013 Jun; 60(6):1022-6.
   View on PubMed
4. Seo Y, Gustafson WC, Dannoon SF, Nekritz EA, Lee CL, Murphy ST, Vanbrocklin HF, Hernandez-Pampaloni M, Haas-Kogan DA, Weiss WA, Matthay KK. Tumor Dosimetry Using [(124)I]m-iodobenzylguanidine MicroPET/CT for [(131)I]m-iodobenzylguanidine Treatment of Neuroblastoma in a Murine Xenograft Model. Mol Imaging Biol. 2012 Dec; 14(6):735-42.
   View on PubMed
5. Tinkle CL, Haas-Kogan D. Hepatocellular carcinoma: natural history, current management, and emerging tools. Biologics. 2012; 6:207-19.
   View on PubMed
6. Mueller S, Phillips J, Onar-Thomas A, Romero E, Zheng S, Wiencke JK, McBride SM, Cowdrey C, Prados MD, Weiss WA, Berger MS, Gupta N, Haas-Kogan DA. PTEN promoter methylation and activation of the PI3K/Akt/mTOR pathway in pediatric gliomas and influence on clinical outcome. Neuro Oncol. 2012 Sep; 14(9):1146-52.
   View on PubMed
7. Cage TA, Mueller S, Haas-Kogan D, Gupta N. High-grade gliomas in children. Neurosurg Clin N Am. 2012 Jul; 23(3):515-23.
   View on PubMed
8. Schoenfeld A, Pekmezci M, Barnes MJ, Tihan T, Gupta N, Lamborn KR, Banerjee A, Mueller S, Chang S, Berger MS, Haas-Kogan D. The superiority of conservative resection and adjuvant radiation for craniopharyngiomas. J Neurooncol. 2012 May; 108(1):133-9.
   View on PubMed
9. Venkatesh HS, Chaumeil MM, Ward CS, Haas-Kogan DA, James CD, Ronen SM. Reduced phosphocholine and hyperpolarized lactate provide magnetic resonance biomarkers of PI3K/Akt/mTOR inhibition in glioblastoma. Neuro Oncol. 2012 Mar; 14(3):315-25.
   View on PubMed
10. Pejavar S, Polley MY, Rosenberg-Wohl S, Chennupati S, Prados MD, Berger MS, Banerjee A, Gupta N, Haas-Kogan D. Pediatric intracranial ependymoma: the roles of surgery, radiation and chemotherapy. J Neurooncol. 2012 Jan; 106(2):367-75.
    View on PubMed
11. Mueller S, Yang X, Sottero TL, Gragg A, Prasad G, Polley MY, Weiss WA, Matthay KK, Davidoff AM, DuBois SG, Haas-Kogan DA. Cooperation of the HDAC inhibitor vorinostat and radiation in metastatic neuroblastoma: efficacy and underlying mechanisms. Cancer Lett. 2011 Jul 28; 306(2):223-9.
    View on PubMed
12. More SS, Itsara M, Yang X, Geier EG, Tadano MK, Seo Y, Vanbrocklin HF, Weiss WA, Mueller S, Haas-Kogan DA, Dubois SG, Matthay KK, Giacomini KM. Vorinostat increases expression of functional norepinephrine transporter in neuroblastoma in vitro and in vivo model systems. Clin Cancer Res. 2011 Apr 15; 17(8):2339-49.
    View on PubMed
13. Polishchuk AL, Dubois SG, Haas-Kogan D, Hawkins R, Matthay KK. Response, survival, and toxicity after iodine-131-metaiodobenzylguanidine therapy for neuroblastoma in preadolescents, adolescents, and adults. Cancer. 2011 Sep 15; 117(18):4286-93.
    View on PubMed
14. Zheng S, Houseman EA, Morrison Z, Wrensch MR, Patoka JS, Ramos C, Haas-Kogan DA, McBride S, Marsit CJ, Christensen BC, Nelson HH, Stokoe D, Wiemels JL, Chang SM, Prados MD, Tihan T, Vandenberg SR, Kelsey KT, Berger MS, Wiencke JK. DNA hypermethylation profiles associated with glioma subtypes and EZH2 and IGFBP2 mRNA expression. Neuro Oncol. 2011 Mar; 13(3):280-9.
    View on PubMed
15. Haas-Kogan DA, Banerjee A, Poussaint TY, Kocak M, Prados MD, Geyer JR, Fouladi M, Broniscer A, Minturn JE, Pollack IF, Packer RJ, Boyett JM, Kun LE. Phase II trial of tipifarnib and radiation in children with newly diagnosed diffuse intrinsic pontine gliomas. Neuro Oncol. 2011 Mar; 13(3):298-306.
    View on PubMed
16. Prasad G, Sottero T, Yang X, Mueller S, James CD, Weiss WA, Polley MY, Ozawa T, Berger MS, Aftab DT, Prados MD, Haas-Kogan DA. Inhibition of PI3K/mTOR pathways in glioblastoma and implications for combination therapy with temozolomide. Neuro Oncol. 2011 Apr; 13(4):384-92.
    View on PubMed
17. Poussaint TY, Kocak M, Vajapeyam S, Packer RI, Robertson RL, Geyer R, Haas-Kogan D, Pollack IF, Vezina G, Zimmerman R, Cha S, Patay Z, Boyett JM, Kun LE. MRI as a central component of clinical trials analysis in brainstem glioma: a report from the Pediatric Brain Tumor Consortium (PBTC). Neuro Oncol. 2011 Apr; 13(4):417-27.
    View on PubMed
18. Zukotynski KA, Fahey FH, Kocak M, Alavi A, Wong TZ, Treves ST, Shulkin BL, Haas-Kogan DA, Geyer JR, Vajapeyam S, Boyett JM, Kun LE, Poussaint TY. Evaluation of 18F-FDG PET and MRI associations in pediatric diffuse intrinsic brain stem glioma: a report from the Pediatric Brain Tumor Consortium. J Nucl Med. 2011 Feb; 52(2):188-95.
    View on PubMed
19. Fan QW, Cheng C, Hackett C, Feldman M, Houseman BT, Nicolaides T, Haas-Kogan D, James CD, Oakes SA, Debnath J, Shokat KM, Weiss WA. Akt and autophagy cooperate to promote survival of drug-resistant glioma. Sci Signal. 2010; 3(147):ra81.
    View on PubMed
20. Prabhu SP, Ng S, Vajapeyam S, Kieran MW, Pollack IF, Geyer R, Haas-Kogan D, Boyett JM, Kun L, Poussaint TY. DTI assessment of the brainstem white matter tracts in pediatric BSG before and after therapy: a report from the Pediatric Brain Tumor Consortium. Childs Nerv Syst. 2011 Jan; 27(1):11-8.
    View on PubMed

View on UCSF Profiles