Akiko Hata, PhD

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Akiko Hata, PhD

Professor, Dept. of Biochemistry & Biophysics, Cardiovascular Research Institute, UCSF

Akiko.Hata@ucsf.edu

Phone: (415) 476-9758
Box 3118, UCSF
San Francisco, CA 94143

UCSF Profiles

Cancer Center Membership

Member » Cancer Genetics

Education

Tokyo University of Science, Tokyo, Japan, B.A., 03/1988, Pharmacy
University of Tokyo, Tokyo, Japan, M.S., 03/1990, Biochemistry
Rockefeller University, NY, Ph.D., 06/1995, Cell Biology


Professional Experience

  • 1995-1998
    Post-doctoral Research Fellow, Cell Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY
  • 1999-2000
    Research Associate, Cell Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY
  • 2000-2008
    Assistant Professor of Biochemistry, Tufts University School of Medicine, Boston, MA
  • 2000-2008
    Assistant Professor of Medicine, Tufts University School of Medicine, Boston, MA
  • 2000-present
    Director of Molecular Signaling Laboratory, Molecular Cardiology Research Institute, Tufts-New England Medical Center, Boston, MA
  • 2008-2011
    Associate Professor of Biochemistry, Tufts University School of Medicine, Boston, MA
  • 2008-2011
    Associate Professor of Medicine, Tufts University School of Medicine, Boston, MA
  • 2011-present
    Professor of Dept. of Biochemistry & Biophysics, Cardiovascular Research Institute, University of California San Francisco

Selected Publications

  1. Celona B, von Dollen J, Vatsavayai SC, Kashima R, Johnson JR, Tang AA, Hata A, Miller BL, Huang EJ, Krogan NJ, Seeley WW, Black BL. Suppression of C9orf72 RNA repeat-induced neurotoxicity by the ALS-associated RNA-binding protein Zfp106. Elife. 2017 Jan 10; 6.
    View on PubMed
  2. Hata A, Chen YG. TGF-ß Signaling from Receptors to Smads. Cold Spring Harb Perspect Biol. 2016; 8(9).
    View on PubMed
  3. Kashima R, Roy S, Ascano M, Martinez-Cerdeno V, Ariza-Torres J, Kim S, Louie J, Lu Y, Leyton P, Bloch KD, Kornberg TB, Hagerman PJ, Hagerman R, Lagna G, Hata A. Augmented noncanonical BMP type II receptor signaling mediates the synaptic abnormality of fragile X syndrome. Sci Signal. 2016; 9(431):ra58.
    View on PubMed
  4. Kang H, Hata A. Quantitative Real-Time PCR Analysis of MicroRNAs and Their Precursors Regulated by TGF-ß Signaling. Methods Mol Biol. 2016; 1344:313-23.
    View on PubMed
  5. Morrell NW, Bloch DB, Ten Dijke P, Goumans MJ, Hata A, Smith J, Yu PB, Bloch KD. Targeting BMP signalling in cardiovascular disease and anaemia. Nat Rev Cardiol. 2016 Feb; 13(2):106-20.
    View on PubMed
  6. Nazer B, Ghahghaie F, Kashima R, Khokhlova T, Perez C, Crum L, Matula T, Hata A. Therapeutic Ultrasound Promotes Reperfusion and Angiogenesis in a Rat Model of Peripheral Arterial Disease. Circ J. 2015; 79(9):2043-9.
    View on PubMed
  7. Kang H, Hata A. The role of microRNAs in cell fate determination of mesenchymal stem cells: balancing adipogenesis and osteogenesis. BMB Rep. 2015 Jun; 48(6):319-23.
    View on PubMed
  8. Cushing L, Costinean S, Xu W, Jiang Z, Madden L, Kuang P, Huang J, Weisman A, Hata A, Croce CM, Lü J. Disruption of miR-29 Leads to Aberrant Differentiation of Smooth Muscle Cells Selectively Associated with Distal Lung Vasculature. PLoS Genet. 2015 May; 11(5):e1005238.
    View on PubMed
  9. Hata A, Lieberman J. Dysregulation of microRNA biogenesis and gene silencing in cancer. Sci Signal. 2015 Mar 17; 8(368):re3.
    View on PubMed
  10. Hata A, Kang H. Functions of the bone morphogenetic protein signaling pathway through microRNAs (review). Int J Mol Med. 2015 Mar; 35(3):563-8.
    View on PubMed
  11. Kim S, Hata A, Kang H. Down-regulation of miR-96 by bone morphogenetic protein signaling is critical for vascular smooth muscle cell phenotype modulation. J Cell Biochem. 2014 May; 115(5):889-95.
    View on PubMed
  12. Nazer B, Gerstenfeld EP, Hata A, Crum LA, Matula TJ. Cardiovascular applications of therapeutic ultrasound. J Interv Card Electrophysiol. 2014 Apr; 39(3):287-94.
    View on PubMed
  13. Chang J, Davis-Dusenbery BN, Kashima R, Jiang X, Marathe N, Sessa R, Louie J, Gu W, Lagna G, Hata A. Acetylation of p53 stimulates miRNA processing and determines cell survival following genotoxic stress. EMBO J. 2013 Dec 11; 32(24):3192-205.
    View on PubMed
  14. Arora P, Wu C, Khan AM, Bloch DB, Davis-Dusenbery BN, Ghorbani A, Spagnolli E, Martinez A, Ryan A, Tainsh LT, Kim S, Rong J, Huan T, Freedman JE, Levy D, Miller KK, Hata A, Del Monte F, Vandenwijngaert S, Swinnen M, Janssens S, Holmes TM, Buys ES, Bloch KD, Newton-Cheh C, Wang TJ. Atrial natriuretic peptide is negatively regulated by microRNA-425. J Clin Invest. 2013 Aug; 123(8):3378-82.
    View on PubMed
  15. Sessa R, Hata A. Role of microRNAs in lung development and pulmonary diseases. Pulm Circ. 2013 Apr; 3(2):315-28.
    View on PubMed
  16. Blahna MT, Hata A. Regulation of miRNA biogenesis as an integrated component of growth factor signaling. Curr Opin Cell Biol. 2013 Apr; 25(2):233-40.
    View on PubMed
  17. Hata A. Functions of microRNAs in cardiovascular biology and disease. Annu Rev Physiol. 2013; 75:69-93.
    View on PubMed
  18. Akhurst RJ, Hata A. Targeting the TGFß signalling pathway in disease. Nat Rev Drug Discov. 2012 Oct; 11(10):790-811.
    View on PubMed
  19. Kang H, Louie J, Weisman A, Sheu-Gruttadauria J, Davis-Dusenbery BN, Lagna G, Hata A. Inhibition of microRNA-302 (miR-302) by bone morphogenetic protein 4 (BMP4) facilitates the BMP signaling pathway. J Biol Chem. 2012 Nov 9; 287(46):38656-64.
    View on PubMed
  20. Wang D, Prakash J, Nguyen P, Davis-Dusenbery BN, Hill NS, Layne MD, Hata A, Lagna G. Bone morphogenetic protein signaling in vascular disease: anti-inflammatory action through myocardin-related transcription factor A. J Biol Chem. 2012 Aug 10; 287(33):28067-77.
    View on PubMed

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