About UCSF Search UCSF UCSF Medical Center

Biao He, PhD

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
he_biao

Associate Adjunct Professor, Department of Surgery, UCSF

bhe@cc.ucsf.edu

Phone: (415) 502-0555
Box 1724, UCSF
San Francisco, CA 94143-1724

View on UCSF Profiles


Education

Tsinghua University, Beijing, China, BS, 1993, Biochemistry
Tsinghua University, Beijing, China, MS, 1995, Biochemistry
University of Virginia, VA, PhD, 2001, Molecular, Cell Biology and Genetics
Comprehensive Cancer Center, University of California, San Francisco, CA, Postdoctoral training, 2002, Molecular, Cell Biology and Signal Transduction


Professional Experience

  • 1994-1995
    Graduate Research Assistant, Department of Biology, Tsinghua University, Beijing, China
  • 1995-1996
    Graduate Research Assistant, Biological Timing Center, University of Virginia, VA
  • 1996-1997
    Graduate Teaching Assistant, Department of Biology, University of Virginia, VA
  • 1997-2001
    Graduate Research Assistant, Department of Biology, University of Virginia, VA
  • 2001-2002
    Postdoctoral Researcher, Cancer Center, University of California San Francisco, CA
  • 2002-2004
    Assistant Research Molecular Biologist, Cancer Center, Univ. of California San Francisco, CA
  • 2004-2009
    Assistant Adjunct Professor, Department of Surgery, University of California San Francisco, CA
  • 2009-present
    Associate Adjunct Professor, Department of Surgery, University of California San Francisco, CA

Honors & Awards

  • 1989
    Honor of Outstanding Student, Tsinghua University, Beijing, China
  • 1990
    Honor of Outstanding Student, Tsinghua University, Beijing, China
  • 1991
    Honor of Outstanding Student, Tsinghua University, Beijing, China
  • 1992
    Guanghua Scholarship, Tsinghua University, Beijing, China
  • 1993
    Honor of Outstanding Graduate, Tsinghua University, Beijing, China
  • 1995
    Hua Luogeng Memorial Fellowship, Tsinghua University, Beijing, China
  • 1995
    Fellowship, University of Virginia, Charlottesville, VA
  • 1996
    Fellowship, University of Virginia, Charlottesville, VA
  • 2004
    Barbara Isackson Endowed Research Fellow, University of California, San Francisco, CA
  • 2007
    Eileen Ludwig Award in Thoracic Oncology Research, Univ. of California, San Francisco, CA

Selected Publications

  1. Kratz JR, Tham PT, Mulvihill MS, Ziaei F, Ray MR, Hurst JW, Segal MR, Berryman DM, Chu W, He B, Jablons DM, Mann MJ. Analytical validation of a practical molecular assay prognostic of survival in nonsquamous non-small cell lung cancer. Diagn Mol Pathol. 2013 Jun; 22(2):65-9.
    View on PubMed
  2. Bosco-Clément G, Zhang F, Chen Z, Zhou HM, Li H, Mikami I, Hirata T, Yagui-Beltran A, Lui N, Do HT, Cheng T, Tseng HH, Choi H, Fang LT, Kim IJ, Yue D, Wang C, Zheng Q, Fujii N, Mann M, Jablons DM, He B. Targeting Gli transcription activation by small molecule suppresses tumor growth. Oncogene. 2014 Apr 17; 33(16):2087-97.
    View on PubMed
  3. Li H, Lui N, Cheng T, Tseng HH, Yue D, Giroux-Leprieur E, Do HT, Sheng Q, Jin JQ, Luh TW, Jablons DM, He B. Gli as a novel therapeutic target in malignant pleural mesothelioma. PLoS One. 2013; 8(3):e57346.
    View on PubMed
  4. Zhang Y, He J, Zhang F, Li H, Yue D, Wang C, Jablons DM, He B, Lui N. SMO expression level correlates with overall survival in patients with malignant pleural mesothelioma. J Exp Clin Cancer Res. 2013; 32:7.
    View on PubMed
  5. Tseng HH, He B. Molecular markers as therapeutic targets in lung cancer. Chin J Cancer. 2013 Feb; 32(2):59-62.
    View on PubMed
  6. Mulvihill MS, Kratz JR, Pham P, Jablons DM, He B. The role of stem cells in airway repair: implications for the origins of lung cancer. Chin J Cancer. 2013 Feb; 32(2):71-4.
    View on PubMed
  7. Kratz JR, He J, Van Den Eeden SK, Zhu ZH, Gao W, Pham PT, Mulvihill MS, Ziaei F, Zhang H, Su B, Zhi X, Quesenberry CP, Habel LA, Deng Q, Wang Z, Zhou J, Li H, Huang MC, Yeh CC, Segal MR, Ray MR, Jones KD, Raz DJ, Xu Z, Jahan TM, Berryman D, He B, Mann MJ, Jablons DM. A practical molecular assay to predict survival in resected non-squamous, non-small-cell lung cancer: development and international validation studies. Lancet. 2012 Mar 3; 379(9818):823-32.
    View on PubMed
  8. Okamoto J, Kratz JR, Hirata T, Mikami I, Raz D, Segal M, Chen Z, Zhou HM, Pham P, Li H, Yagui-Beltran A, Beltran A, Ray MR, Koizumi K, Shimizu K, Jablons D, He B. Downregulation of EMX2 is associated with clinical outcomes in lung adenocarcinoma patients. Clin Lung Cancer. 2011 Jul; 12(4):237-44.
    View on PubMed
  9. Mikami I, Zhang F, Hirata T, Okamoto J, Koizumi K, Shimizu K, Jablons D, He B. Inhibition of activated phosphatidylinositol 3-kinase/AKT pathway in malignant pleural mesothelioma leads to G1 cell cycle arrest. Oncol Rep. 2010 Dec; 24(6):1677-81.
    View on PubMed
  10. Ray MR, Jablons D, He B. Lung cancer therapeutics that target signaling pathways: an update. Expert Rev Respir Med. 2010 Oct; 4(5):631-45.
    View on PubMed
  11. Okamoto J, Hirata T, Chen Z, Zhou HM, Mikami I, Li H, Yagui-Beltran A, Beltran A, Johansson M, Coussens LM, Clement G, Shi Y, Zhang F, Koizumi K, Shimizu K, Jablons D, He B. EMX2 is epigenetically silenced and suppresses growth in human lung cancer. Oncogene. 2010 Nov 4; 29(44):5969-75.
    View on PubMed
  12. Lemjabbar-Alaoui H, van Zante A, Singer MS, Xue Q, Wang YQ, Tsay D, He B, Jablons DM, Rosen SD. Sulf-2, a heparan sulfate endosulfatase, promotes human lung carcinogenesis. Oncogene. 2010 Feb 4; 29(5):635-46.
    View on PubMed
  13. Yagui-Beltrán A, He B, Jablons DM. The role of cancer stem cells in neoplasia of the lung: past, present and future. Clin Transl Oncol. 2008 Nov; 10(11):719-25.
    View on PubMed
  14. Okamoto J, Mikami I, Tominaga Y, Kuchenbecker KM, Lin YC, Bravo DT, Clement G, Yagui-Beltran A, Ray MR, Koizumi K, He B, Jablons DM. Inhibition of Hsp90 leads to cell cycle arrest and apoptosis in human malignant pleural mesothelioma. J Thorac Oncol. 2008 Oct; 3(10):1089-95.
    View on PubMed
  15. Raz DJ, Ray MR, Kim JY, He B, Taron M, Skrzypski M, Segal M, Gandara DR, Rosell R, Jablons DM. A multigene assay is prognostic of survival in patients with early-stage lung adenocarcinoma. Clin Cancer Res. 2008 Sep 1; 14(17):5565-70.
    View on PubMed
  16. Chou J, Lin YC, Kim J, You L, Xu Z, He B, Jablons DM. Nasopharyngeal carcinoma--review of the molecular mechanisms of tumorigenesis. Head Neck. 2008 Jul; 30(7):946-63.
    View on PubMed
  17. Clément G, Guilleret I, He B, Yagui-Beltrán A, Lin YC, You L, Xu Z, Shi Y, Okamoto J, Benhattar J, Jablons D. Epigenetic alteration of the Wnt inhibitory factor-1 promoter occurs early in the carcinogenesis of Barrett's esophagus. Cancer Sci. 2008 Jan; 99(1):46-53.
    View on PubMed
  18. Shi Y, He B, Kuchenbecker KM, You L, Xu Z, Mikami I, Yagui-Beltran A, Clement G, Lin YC, Okamoto J, Bravo DT, Jablons DM. Inhibition of Wnt-2 and galectin-3 synergistically destabilizes beta-catenin and induces apoptosis in human colorectal cancer cells. Int J Cancer. 2007 Sep 15; 121(6):1175-81.
    View on PubMed
  19. Shi Y, He B, You L, Jablons DM. Roles of secreted frizzled-related proteins in cancer. Acta Pharmacol Sin. 2007 Sep; 28(9):1499-504.
    View on PubMed
  20. Lee AY, Raz DJ, He B, Jablons DM. Update on the molecular biology of malignant mesothelioma. Cancer. 2007 Apr 15; 109(8):1454-61.
    View on PubMed

Go to UCSF Profiles, powered by CTSI