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Andrew Hsieh, MD


Assistant Adjunct Professor, Division of Hematology/Oncology, UCSF

Phone: 415-353-7171

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UC Berkeley, Berkeley, CA B.A. 1996-1999 Cell Biology
Albert Einstein College of Medicine, Bronx, NY M.D. 2000-2005 Medicine
UCSF Internal Medicine Residency, SF, CA 2005-2007 Internal Medicine
UCSF Oncology Fellowship, SF, CA 2007-2011 Oncology
Postdoctoral Fellow (PI – Davide Ruggero PhD) 2008-Current Cancer Biology

Professional Experience

  • 1997 – 1999
    Undergraduate Researcher (Mentor – Gary L. Firestone, PhD), UC Berkeley, Berkeley, CA
  • 2001 – 2003
    Research Fellow (Mentor – William R. Sellers, MD), Dana Farber Cancer Institute, Boston, MA
  • 2005 – 2007
    Internal Medicine Resident, UCSF, San Francisco, CA
  • 2005 – 2011
    Molecular Medicine Training Program, UCSF, San Francisco, CA
  • 2007 – 2011
    Oncology Fellow, UCSF, San Francisco, CA
  • 2008 – Present
    Post-doctoral Fellow (Mentor – Davide Ruggero, PhD), UCSF, San Francisco, CA
  • 2011 – 2013
    Instructor, Division of Hematology/Oncology, UCSF, San Francisco, CA
  • 2013 - Present
    Assistant Adjunct Professor, Division of Hematology/Oncology, UCSF, San Francisco, CA


Honors & Awards

  • 1998
    Golden Key Honor Society
  • 1998
    UC Berkeley President’s Undergraduate Fellowship
  • 1999
    Phi Beta Kappa
  • 1999
    Chaikoff Award for Biological Research
  • 2001
    American Federation for Aging Research Scholarship for Aging Research
  • 2002
    Howard Hughes Medical Institute Medical Student Fellow
  • 2003
    Academy of Achievement International Honor Delegate
  • 2003
    Howard Hughes Medical Institute Continuing Support Award
  • 2004
    Albert Einstein College of Medicine Global Health Fellowship
  • 2005
    Alpha Omega Alpha Honor Society
  • 2005
    Albert Einstein College of Medicine Distinction in Cancer Research
  • 2008
    NIH T32 award - Basic Research in Hematology and Oncology
  • 2009
    AACR Scholar-in-Training Award
  • 2009
    Best Laboratory Science Poster – UCSF Prostate Cancer Program Retreat
  • 2010
    AACR-Astellas USA Foundation Fellowship in Clinical/Translational Cancer Research (declined)
  • 2010
    ASCO Young Investigator Award
  • 2010
    NIH Loan Repayment Program
  • 2010
    American Cancer Society Postdoctoral Fellowship
  • 2010
    Prostate Cancer Foundation Young Investigator Award
  • 2011
    DOD Prostate Cancer Training Award
  • 2012
    27th Annual Aspen Cancer Conference Fellow
  • 2013
    NIH K08 award 1K08CA175154 from the NCI
  • 2013
    Burroughs Wellcome Fund Career Award for Medical Scientists

Selected Publications

  1. Edlind MP, Hsieh AC. PI3K-AKT-mTOR signaling in prostate cancer progression and androgen deprivation therapy resistance. Asian J Androl. 2014 May-Jun; 16(3):378-86.
    View on PubMed
  2. Olshen AB, Hsieh AC, Stumpf CR, Olshen RA, Ruggero D, Taylor BS. Assessing gene-level translational control from ribosome profiling. Bioinformatics. 2013 Dec 1; 29(23):2995-3002.
    View on PubMed
  3. Hsieh AC, Liu Y, Edlind MP, Ingolia NT, Janes MR, Sher A, Shi EY, Stumpf CR, Christensen C, Bonham MJ, Wang S, Ren P, Martin M, Jessen K, Feldman ME, Weissman JS, Shokat KM, Rommel C, Ruggero D. The translational landscape of mTOR signalling steers cancer initiation and metastasis. Nature. 2012 May 3; 485(7396):55-61.
    View on PubMed
  4. Hsieh AC, Truitt ML, Ruggero D. Oncogenic AKTivation of translation as a therapeutic target. Br J Cancer. 2011 Jul 26; 105(3):329-36.
    View on PubMed
  5. Kondrashov N, Pusic A, Stumpf CR, Shimizu K, Hsieh AC, Xue S, Ishijima J, Shiroishi T, Barna M. Ribosome-mediated specificity in Hox mRNA translation and vertebrate tissue patterning. Cell. 2011 Apr 29; 145(3):383-97.
    View on PubMed
  6. Hsieh AC, Ruggero D. Targeting eukaryotic translation initiation factor 4E (eIF4E) in cancer. Clin Cancer Res. 2010 Oct 15; 16(20):4914-20.
    View on PubMed
  7. Hsieh AC, Costa M, Zollo O, Davis C, Feldman ME, Testa JR, Meyuhas O, Shokat KM, Ruggero D. Genetic dissection of the oncogenic mTOR pathway reveals druggable addiction to translational control via 4EBP-eIF4E. Cancer Cell. 2010 Mar 16; 17(3):249-61.
    View on PubMed
  8. Hsieh AC, Ryan CJ. Novel concepts in androgen receptor blockade. Cancer J. 2008 Jan-Feb; 14(1):11-4.
    View on PubMed
  9. Hsieh AC, Small EJ, Ryan CJ. Androgen-response elements in hormone-refractory prostate cancer: implications for treatment development. Lancet Oncol. 2007 Oct; 8(10):933-9.
    View on PubMed
  10. Hsieh AC, Moasser MM. Targeting HER proteins in cancer therapy and the role of the non-target HER3. Br J Cancer. 2007 Aug 20; 97(4):453-7.
    View on PubMed

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