University of California San Francisco
Helen Diller Family Comprehensive Cancer Center
Kord Kober, PhD

Kord Kober, PhD

Assistant Professor, Physiological Nursing, UCSF

Cancer Center Program Memberships

Breast Oncology

Research Summary

Dr. Kober is highly qualified to serve as a co-investigator, geneticist and bioinformatician for the proposed project. Dr. Kober has worked in this capacity both in the Academic (e.g., UC Santa Cruz Genome Browser) and non-Academic (e.g., Navigenics, Inc) environments. He has in-depth experience in computer science, biochemistry, and molecular evolution, the later which requires considered expertise in bioinformatics (i.e., scripting languages, data management and visualization, interrogation and deposition of data into public databases with strict formatting requirements). He has experience in molecular analysis of cancer related symptoms. He has worked both at the wet bench (i.e., molecular biologist) and in the dry laboratory (i.e., Bioinformatician) for over 10 years. He is experienced with the molecular and data analytic procedures described in the current application. Of note, Dr. Kober plays a key role in an NIH-funded Biostatistics and Bioinformatics Group as part of the NIH NIAID-funded Women’s Interagency HIV Study (WIHS), which currently focused primarily on genome wide association studies and large-scale molecular data analyses. He will bring these experiences to the proposed project.

Education

University of California, Los Angeles, BS, 06/96, Biochemistry
University of California, Santa Cruz, MA, 06/09, Molecular Evolutionary Biology
University of California, Santa Cruz, PhD, 06/12, Molecular Evolutionary Biology


Professional Experience

  • 1997-2000
    Programmer Analyst, Information Services & Technology, UC Berkeley
  • 2000-2004
    Unix Systems Architect, eCommerce, Moët Hennessy Louis Vuitton S.A. & Prosodie Interactive
  • 2000-present
    Founder, Board member, Secretary, Treasurer, Benjamin Links. A 501(c)3 public benefit charity for families of children with Autism.
  • 2004-2005
    Director, eCommerce, Moët Hennessy Louis Vuitton S.A. & Prosodie Interactive
  • 2006-2008
    Research Associate (Molecular Genetics), Physiological Nursing, UCSF School of Nursing
  • 2008-2009
    Bioinformatics Consultant (Personal Genomics), Research and Development, Navigenics, Inc.
  • 2010-2011
    Biological Data Engineer (Cancer Genomics), Cancer Genome Browser, UC Santa Cruz
  • 2011-2011
    Bioinformatics Consultant (Personal Genomics), Research and Development, Navigenics, Inc.
  • 2011-2013
    Bioinformaticist (Genomics of Human Disease), Physiological Nursing/ WIHS Genomics Unit, UCSF School of Nursing
  • 2013-present
    Assistant Professor, Physiological Nursing, UCSF School of Nursing
  • 2013-present
    Vice-Chair, UCSF Genomics Working Group, Women's Interagency HIV Study

Honors & Awards

  • 2006
    Regents' Fellowship, University of California, Santa Cruz, CA
  • 2007
    STEPS Institute Graduate Research Grant Award, University of California, Santa Cruz, CA
  • 2007
    Summer Research Fellowship, Dept. of EE Biology, University Of California, Santa Cruz, CA
  • 2007
    Student Research and Education Award, Friends of Long Marine Lab, Santa Cruz, CA
  • 2008
    Summer Research Fellowship, Dept. of EE Biology, University Of California, Santa Cruz, CA
  • 2011
    Graduate Student Support Award, CSHL Meeting on The Biology of Genomes
  • 2011
    Research Award, Dr. Earl H. Myers and Ethel M. Myers Oceonographic and Marine Biology Trust
  • 2013
    Annual Meeting Best Poster Nominee, American Pain Society
  • 2014
    New Investigator Abstract Award (Fatigue Study Group), MASCC
  • 2015
    Faculty Learning and Development, UCSF Chancellor’s Fund

Selected Publications

  1. Singh KP, Kober KM, Dhruva AA, Flowers E, Paul SM, Hammer MJ, Cartwright F, Wright F, Conley YP, Levine JD, Miaskowski C. Risk Factors Associated With Chemotherapy-Induced Nausea in the Week Prior to the Next Cycle and Impact of Nausea on Quality of Life Outcomes. J Pain Symptom Manage. 2018 May 29.
    View on PubMed
  2. Knisely MR, Conley YP, Kober KM, Smoot B, Paul SM, Levine JD, Miaskowski C. Associations Between Catecholaminergic and Serotonergic Genes and Persistent Breast Pain Phenotypes Following Breast Cancer Surgery. J Pain. 2018 Apr 30.
    View on PubMed
  3. Tantoy IY, Cooper BA, Dhruva A, Cataldo J, Paul SM, Conley YP, Hammer M, Kober KM, Levine JD, Miaskowski C. Quality of life of patients with gastrointestinal cancers undergoing chemotherapy. Qual Life Res. 2018 Apr 21.
    View on PubMed
  4. Carrico AW, Flentje A, Kober K, Lee S, Hunt P, Riley ED, Shoptaw S, Flowers E, Dilworth SE, Pahwa S, Aouizerat BE. Recent stimulant use and leukocyte gene expression in methamphetamine users with treated HIV infection. Brain Behav Immun. 2018 Apr 18.
    View on PubMed
  5. Flentje A, Kober K, Carrico A, Neilands TB, Flowers E, Heck N, Aouizerat B. Minority Stress and Leukocyte Gene Expression in Sexual Minority Men Living with Treated HIV Infection. Brain Behav Immun. 2018 Mar 13.
    View on PubMed
  6. Miaskowski C, Paul SM, Mastick J, Abrams G, Topp K, Smoot B, Kober KM, Chesney M, Mazor M, Mausisa G, Schumacher M, Conley YP, Sabes JH, Cheung S, Wallhagen M, Levine JD. Associations Between Perceived Stress and Chemotherapy-Induced Peripheral Neuropathy and Otoxicity in Adult Cancer Survivors. J Pain Symptom Manage. 2018 Mar 07.
    View on PubMed
  7. Singh KP, Miaskowski C, Dhruva AA, Flowers E, Kober KM. Mechanisms and Measurement of Changes in Gene Expression. Biol Res Nurs. 2018 Jan 01; 1099800418772161.
    View on PubMed
  8. Singh KP, Dhruva AA, Flowers E, Kober KM, Miaskowski C. A review of the literature on the relationships between genetic polymorphisms and chemotherapy-induced nausea and vomiting. Crit Rev Oncol Hematol. 2018 Jan; 121:51-61.
    View on PubMed
  9. Miaskowski C, Mastick J, Paul SM, Abrams G, Cheung S, Sabes JH, Kober KM, Schumacher M, Conley YP, Topp K, Smoot B, Mausisa G, Mazor M, Wallhagen M, Levine JD. Impact of chemotherapy-induced neurotoxicities on adult cancer survivors' symptom burden and quality of life. J Cancer Surviv. 2017 Nov 20.
    View on PubMed
  10. Miaskowski C, Paul SM, Mastick J, Schumacher M, Conley YP, Smoot B, Abrams G, Kober KM, Cheung S, Henderson-Sabes J, Chesney M, Mazor M, Wallhagen M, Levine JD. Hearing loss and tinnitus in survivors with chemotherapy-induced neuropathy. Eur J Oncol Nurs. 2018 Feb; 32:1-11.
    View on PubMed
  11. Dapp MJ, Kober KM, Chen L, Westfall DH, Wong K, Zhao H, Hall BM, Deng W, Sibley T, Ghorai S, Kim K, Chen N, McHugh S, Au L, Cohen M, Anastos K, Mullins JI. Patterns and rates of viral evolution in HIV-1 subtype B infected females and males. PLoS One. 2017; 12(10):e0182443.
    View on PubMed
  12. Saarman NP, Kober KM, Simison WB, Pogson GH. Sequence-Based Analysis of Thermal Adaptation and Protein Energy Landscapes in an Invasive Blue Mussel (Mytilus galloprovincialis). Genome Biol Evol. 2017 Oct 01; 9(10):2739-2751.
    View on PubMed
  13. Flowers E, Miaskowski C, Conley Y, Hammer MJ, Levine J, Mastick J, Paul S, Wright F, Kober K. Differential expression of genes and differentially perturbed pathways associated with very high evening fatigue in oncology patients receiving chemotherapy. Support Care Cancer. 2018 Mar; 26(3):739-750.
    View on PubMed
  14. Papachristou N, Barnaghi P, Cooper BA, Hu X, Maguire R, Apostolidis K, Armes J, Conley YP, Hammer M, Katsaragakis S, Kober KM, Levine JD, McCann L, Patiraki E, Paul SM, Ream E, Wright F, Miaskowski C. Congruence Between Latent Class and K-Modes Analyses in the Identification of Oncology Patients With Distinct Symptom Experiences. J Pain Symptom Manage. 2018 Feb; 55(2):318-333.e4.
    View on PubMed
  15. Miaskowski C, Conley YP, Mastick J, Paul SM, Cooper BA, Levine JD, Knisely M, Kober KM. Cytokine Gene Polymorphisms Associated With Symptom Clusters in Oncology Patients Undergoing Radiation Therapy. J Pain Symptom Manage. 2017 Sep; 54(3):305-316.e3.
    View on PubMed
  16. Park SY, Love TMT, Reynell L, Yu C, Kang TM, Anastos K, DeHovitz J, Liu C, Kober KM, Cohen M, Mack WJ, Lee HY. The HIV Genomic Incidence Assay Meets False Recency Rate and Mean Duration of Recency Infection Performance Standards. Sci Rep. 2017 Aug 07; 7(1):7480.
    View on PubMed
  17. Kober KM, Pogson GH. Genome-wide signals of positive selection in strongylocentrotid sea urchins. BMC Genomics. 2017 07 21; 18(1):555.
    View on PubMed
  18. Wright F, Cooper BA, Conley YP, Hammer MJ, Chen LM, Paul SM, Levine JD, Miaskowski C, Kober KM. Distinct Evening Fatigue Profiles in Oncology Outpatients Receiving Chemotherapy. Fatigue. 2017; 5(3):131-144.
    View on PubMed
  19. Smoot B, Kober KM, Paul SM, Levine JD, Abrams G, Mastick J, Topp K, Conley YP, Miaskowski CA. Potassium Channel Candidate Genes Predict the Development of Secondary Lymphedema Following Breast Cancer Surgery. Nurs Res. 2017 Mar/Apr; 66(2):85-94.
    View on PubMed
  20. Kober KM, Bernardi G. Erratum to: Phylogenomics of strongylocentrotid sea urchins. BMC Evol Biol. 2017 02 13; 17(1):50.
    View on PubMed

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