Lorriana Leard, MD

Lorriana Leard, MD

Professor of Clinical Medicine; Vice Chief of Clinical Activities, Pulmonary, Critical Care, Allergy & Sleep Medicine; Associate Director, Pulmonary & Critical Care Fellowship Program, UCSF

Phone: (415) 885-3882

Box 0111, UCSF
San Francisco, CA 94143-0111

Physician Biography

UCSF Profiles

Research Summary

Dr. Lorri Leard received her undergraduate degree from Stanford University and her M.D. from the University of California San Diego. After completing her Internal Medicine residency at the University of Texas Southwestern in Dallas, she came to the University of California San Francisco for her Pulmonary and Critical Care Fellowship. She completed an additional subspecialty fellowship in Lung Transplantation at the University of California San Francisco and joined the faculty in 2006. She pursued further training in medical education in the UCSF Teaching Scholars program and was selected to join the Academy of Medical Educators in 2011.

Dr. Leard is Vice Chief of Clinical Operations for the UCSF Division of Pulmonary, Critical Care, Allergy and Sleep Medicine and a Coach for UCSF medical students. Her major academic interests include Medical Education, Lung Transplantation and Lung Cancer. She cares for patients on the Advanced Lung Disease Service at UCSF Moffitt-Long Hospital, and sees patients at the Mt. Zion Comprehensive Cancer Center.

She is a past president of the California Thoracic Society. She serves on Item Review Committees for the National Board of Medical Educators and is an Editorial Board Consultant for the Journal of Heart and Lung Transplantation.

Education

  • 2019 - Relationship-Centered Communication Skills for Racial Equity in Healthcare, University of California
  • 2018 - Diversity, Equity, and Inclusion Champion Training, University of California
  • Fellowship, 2006 - Lung Transplantation, University of California
  • Fellowship, 2005 - Pulmonary and Critical Care Medicine, University of California
  • Internship & Residency, 2001 - Internal Medicine, University of Texas Southwestern
  • M.D., 1998 - School of Medicine, University of California

Honors & Awards

  • V. Courtney Broaddus Award for Leadership and Service, UCSF, 2022
  • Academy of Medical Educators, UCSF, 2011
  • Michael S. Stulbarg Outstanding Teaching Award, UCSF, 2007

Selected Publications

  1. Santos J, Wang P, Shemesh A, Liu F, Tsao T, Aguilar OA, Cleary SJ, Singer JP, Gao Y, Hays SR, Golden J, Leard LE, Kleinhenz ME, Kolaitis NA, Shah RJ, Venado A, Kukreja J, Weigt SS, Belperio JA, Lanier LL, Looney MR, Greenland JR, Calabrese DR. CCR5 drives NK cell-associated airway damage in pulmonary ischemia-reperfusion injury. JCI Insight. 2023 Oct 03.  View on PubMed
  2. Santos J, Hays SR, Golden JA, Calabrese DR, Kolaitis N, Kleinhenz ME, Shah R, Estrada AV, Leard LE, Kukreja J, Singer JP, Greenland JR. Decreased Lymphocytic Bronchitis Severity in the Era of Azithromycin Prophylaxis. Transplant Direct. 2023 Sep; 9(9):e1495.  View on PubMed
  3. Singer JP, Christie JD, Diamond JM, Anderson MA, Benvenuto LA, Gao Y, Arcasoy SM, Lederer DJ, Calabrese D, Wang P, Hays SR, Kukreja J, Venado A, Kolaitis NA, Leard LE, Shah RJ, Kleinhenz ME, Golden J, Betancourt L, Oyster M, Zaleski D, Adler J, Kalman L, Balar P, Patel S, Medikonda N, Koons B, Tevald M, Covinsky KE, Greenland JR, Katz PK. Development of the Lung Transplant Frailty Scale (LT-FS). J Heart Lung Transplant. 2023 Jul; 42(7):892-904.  View on PubMed
  4. Odisho AY, Liu AW, Maiorano AR, Bigazzi MOA, Medina E, Leard LE, Shah R, Venado A, Perez A, Golden J, Kleinhenz ME, Kolaitis NA, Maheshwari J, Trinh BN, Kukreja J, Greenland J, Calabrese D, Neinstein AB, Singer JP, Hays SR. Design and implementation of a digital health home spirometry intervention for remote monitoring of lung transplant function. J Heart Lung Transplant. 2023 06; 42(6):828-837.  View on PubMed
  5. Kolaitis NA, Chen H, Calabrese DR, Kumar K, Obata J, Bach C, Golden JA, Simon MA, Kukreja J, Hays SR, Leard LE, Singer JP, De Marco T. The Lung Allocation Score Remains Inequitable for Patients with Pulmonary Arterial Hypertension, Even after the 2015 Revision. Am J Respir Crit Care Med. 2023 02 01; 207(3):300-311.  View on PubMed
  6. Calabrese DR, Chong T, Singer JP, Rajalingam R, Hays SR, Kukreja J, Leard L, Golden JA, Lanier LL, Greenland JR. CD16+ natural killer cells in bronchoalveolar lavage are associated with antibody-mediated rejection and chronic lung allograft dysfunction. Am J Transplant. 2023 01; 23(1):37-44.  View on PubMed
  7. Calabrese DR, Tsao T, Magnen M, Valet C, Gao Y, Mallavia B, Tian JJ, Aminian EA, Wang KM, Shemesh A, Punzalan EB, Sarma A, Calfee CS, Christenson SA, Langelier CR, Hays SR, Golden JA, Leard LE, Kleinhenz ME, Kolaitis NA, Shah R, Venado A, Lanier LL, Greenland JR, Sayah DM, Ardehali A, Kukreja J, Weigt SS, Belperio JA, Singer JP, Looney MR. NKG2D receptor activation drives primary graft dysfunction severity and poor lung transplantation outcomes. JCI Insight. 2022 12 22; 7(24).  View on PubMed
  8. Wood DE, Kazerooni EA, Aberle D, Berman A, Brown LM, Eapen GA, Ettinger DS, Ferguson JS, Hou L, Kadaria D, Klippenstein D, Kumar R, Lackner RP, Leard LE, Lennes IT, Leung ANC, Mazzone P, Merritt RE, Midthun DE, Onaitis M, Pipavath S, Pratt C, Puri V, Raz D, Reddy C, Reid ME, Sandler KL, Sands J, Schabath MB, Studts JL, Tanoue L, Tong BC, Travis WD, Wei B, Westover K, Yang SC, McCullough B, Hughes M. NCCN Guidelines® Insights: Lung Cancer Screening, Version 1.2022. J Natl Compr Canc Netw. 2022 07; 20(7):754-764.  View on PubMed
  9. Solomon M, Willemse BWM, Ramos KJ, Leard LE. Response to selection of lung transplant candidates: A pediatric perspective on the ISHLT consensus document. J Heart Lung Transplant. 2022 07; 41(7):1000-1001.  View on PubMed
  10. Kolaitis NA, Gao Y, Soong A, Greenland JR, Hays SR, Golden JA, Venado A, Leard LE, Shah RJ, Kleinhenz ME, Katz PP, Kukreja J, Blanc PD, Smith PJ, Singer JP. Depressive symptoms in lung transplant recipients: trajectory and association with mortality and allograft dysfunction. Thorax. 2022 09; 77(9):891-899.  View on PubMed
  11. Greenland NY, Deiter F, Calabrese DR, Hays SR, Kukreja J, Leard LE, Kolaitis NA, Golden JA, Singer JP, Greenland JR. Inflammation on bronchoalveolar lavage cytology is associated with decreased chronic lung allograft dysfunction-free survival. Clin Transplant. 2022 06; 36(6):e14639.  View on PubMed
  12. Warrior K, Leard LE, Nair AR, Gries CJ, Fisher AJ, Johnson SR, McCormack FX, Dilling DF. A survey of use of mTOR inhibitors in patients with lymphangioleiomyomatosis listed for lung transplant. Respir Med. 2022 Apr-May; 195:106779.  View on PubMed
  13. Perez AA, Leard LE. What's in a name: The importance of lung transplant at Cystic Fibrosis Foundation Accredited Care Centers for patients with Cystic Fibrosis. J Heart Lung Transplant. 2022 03; 41(3):308-310.  View on PubMed
  14. Dugger DT, Calabrese DR, Gao Y, Deiter F, Tsao T, Maheshwari J, Hays SR, Leard L, Kleinhenz ME, Shah R, Golden J, Kukreja J, Gordon ED, Singer JP, Greenland JR. Lung Allograft Epithelium DNA Methylation Age Is Associated With Graft Chronologic Age and Primary Graft Dysfunction. Front Immunol. 2021; 12:704172.  View on PubMed
  15. Maheshwari JA, Kolaitis NA, Anderson MR, Benvenuto L, Gao Y, Katz PP, Greenland J, Wolters PJ, Covinsky K, Hays SR, Kukreja J, Calabrese DR, Venado A, Shah RJ, Leard LE, Trinh B, Huang CY, Glidden D, Kleinhenz ME, Golden JA, Sutter N, Tietje-Ulrich G, Criner RN, Arcasoy SM, Christie JD, Diamond J, Singer JP. Construct and Predictive Validity of Sarcopenia in Lung Transplant Candidates. Ann Am Thorac Soc. 2021 09; 18(9):1464-1474.  View on PubMed
  16. Lew J, Casey M, Leard LE, Hays S, Otani IM. Perceptions Around Lung Transplant-Associated Hypogammaglobulinemia. J Clin Immunol. 2021 11; 41(8):1940-1942.  View on PubMed
  17. Leard LE, Holm AM, Valapour M, Glanville AR, Attawar S, Aversa M, Campos SV, Christon LM, Cypel M, Dellgren G, Hartwig MG, Kapnadak SG, Kolaitis NA, Kotloff RM, Patterson CM, Shlobin OA, Smith PJ, Solé A, Solomon M, Weill D, Wijsenbeek MS, Willemse BWM, Arcasoy SM, Ramos KJ. Consensus document for the selection of lung transplant candidates: An update from the International Society for Heart and Lung Transplantation. J Heart Lung Transplant. 2021 11; 40(11):1349-1379.  View on PubMed
  18. DeBolt CL, Gao Y, Sutter N, Soong A, Leard L, Jeffrey G, Kleinhenz ME, Calabrese D, Greenland J, Venado A, Hays SR, Shah R, Kukreja J, Trinh B, Kolaitis NA, Douglas V, Diamond JM, Smith P, Singer J. The association of post-operative delirium with patient-reported outcomes and mortality after lung transplantation. Clin Transplant. 2021 05; 35(5):e14275.  View on PubMed
  19. Tsou S, Chen J, Brzezinski M, Hays S, Leard L, Singer JP, Trinh B, Kukreja J. Lung transplantation from swimming pool drowning victims: A case series. Am J Transplant. 2021 06; 21(6):2273-2278.  View on PubMed
  20. Iasella CJ, Hoji A, Popescu I, Wei J, Snyder ME, Zhang Y, Xu W, Iouchmanov V, Koshy R, Brown M, Fung M, Langelier C, Lendermon EA, Dugger D, Shah R, Lee J, Johnson B, Golden J, Leard LE, Ellen Kleinhenz M, Kilaru S, Hays SR, Singer JP, Sanchez PG, Morrell MR, Pilewski JM, Greenland JR, Chen K, McDyer JF. Type-1 immunity and endogenous immune regulators predominate in the airway transcriptome during chronic lung allograft dysfunction. Am J Transplant. 2021 06; 21(6):2145-2160.  View on PubMed

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