
Joachim J. Li, MD, PhD
Associate Professor, Department of Microbiology and Immunology, UCSF
Cancer Center Program Memberships
Cancer GeneticsEducation
University of Chicago, Chicago, IL, B.S., M.S., 1980, Chemistry
Johns Hopkins University School of Medicine, Baltimore, MD, M.D., Ph.D., 1988, Medicine/Molecular Biology
Professional Experience
-
1980-1982, 1987-1988
Medical Student, Johns Hopkins University School of Medicine, Baltimore, MD -
1982-1987
Graduate Student (Thomas J. Kelly), Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD -
1988
Postdoctoral Fellow,Yeast Genetics (Phil Hieter), Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD -
1989-1993
Postdoctoral Fellow, Yeast Genetics/Molecular Biology (Ira Herskowitz), Department of Biochemistry and Biophysics, University of California-San Francisco, San Francisco, CA -
1993-2000
Assistant Professor, Department of Microbiology and Immunology, University of California-San Francisco, San Francisco, CA -
2000-present
Associate Professor, Department of Microbiology and Immunology, University of California-San Francisco, San Francisco, CA
Honors & Awards
- 1977
United States Presidential Scholar - 1979
Phi Beta Kappa - 1979-1980
National Science Foundation Graduate Fellow - 1987
Michael A. Shanoff Research Award for Ph.D. Thesis, Johns Hopkins University School of Medicine - 1989-1990
Squibb Fellow, Life Sciences Research Foundation - 1990-1997
Markey Scholar Award - 1994-1999
Rita Allen Scholar - 1995-1998
Searle Scholar - 1998
Distinction in Teaching Award, UCSF
Selected Publications
- Hanlon SL, Li JJ. Re-replication of a centromere induces chromosomal instability and aneuploidy. PLoS Genet. 2015 Apr; 11(4):e1005039.
View on PubMed - Richardson CD, Li JJ. Regulatory mechanisms that prevent re-initiation of DNA replication can be locally modulated at origins by nearby sequence elements. PLoS Genet. 2014 Jun; 10(6):e1004358.
View on PubMed - Green BM, Finn KJ, Li JJ. Loss of DNA replication control is a potent inducer of gene amplification. Science. 2010 Aug 20; 329(5994):943-6.
View on PubMed - Moses AM, Liku ME, Li JJ, Durbin R. Regulatory evolution in proteins by turnover and lineage-specific changes of cyclin-dependent kinase consensus sites. Proc Natl Acad Sci U S A. 2007 Nov 06; 104(45):17713-8.
View on PubMed - Green BM, Morreale RJ, Ozaydin B, Derisi JL, Li JJ. Genome-wide mapping of DNA synthesis in Saccharomyces cerevisiae reveals that mechanisms preventing reinitiation of DNA replication are not redundant. Mol Biol Cell. 2006 May; 17(5):2401-14.
View on PubMed - Liku ME, Nguyen VQ, Rosales AW, Irie K, Li JJ. CDK phosphorylation of a novel NLS-NES module distributed between two subunits of the Mcm2-7 complex prevents chromosomal rereplication. Mol Biol Cell. 2005 Oct; 16(10):5026-39.
View on PubMed - Green BM, Li JJ. Loss of rereplication control in Saccharomyces cerevisiae results in extensive DNA damage. Mol Biol Cell. 2005 Jan; 16(1):421-32.
View on PubMed