Joachim J. Li, MD, PhD

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Joachim J. Li, MD, PhD

Associate Professor, Department of Microbiology and Immunology, UCSF

jli@itsa.ucsf.edu

Phone: (415) 476-8782, 476-3841, 514-4081 (voice)
Box 2200, UCSF
San Francisco, CA 94143-2200

View on UCSF Profiles

Cancer Center Membership

Program Member ยป Cancer Genetics

Additional Websites


Education

University of Chicago, Chicago, IL, B.S., M.S., 1980, Chemistry
Johns Hopkins University School of Medicine, Baltimore, MD, M.D., Ph.D., 1988, Medicine/Molecular Biology


Professional Experience

  • 1980-1982, 1987-1988
    Medical Student, Johns Hopkins University School of Medicine, Baltimore, MD
  • 1982-1987
    Graduate Student (Thomas J. Kelly), Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD
  • 1988
    Postdoctoral Fellow,Yeast Genetics (Phil Hieter), Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD
  • 1989-1993
    Postdoctoral Fellow, Yeast Genetics/Molecular Biology (Ira Herskowitz), Department of Biochemistry and Biophysics, University of California-San Francisco, San Francisco, CA
  • 1993-2000
    Assistant Professor, Department of Microbiology and Immunology, University of California-San Francisco, San Francisco, CA
  • 2000-present
    Associate Professor, Department of Microbiology and Immunology, University of California-San Francisco, San Francisco, CA

Honors & Awards

  • 1977
    United States Presidential Scholar
  • 1979
    Phi Beta Kappa
  • 1979-1980
    National Science Foundation Graduate Fellow
  • 1987
    Michael A. Shanoff Research Award for Ph.D. Thesis, Johns Hopkins University School of Medicine
  • 1989-1990
    Squibb Fellow, Life Sciences Research Foundation
  • 1990-1997
    Markey Scholar Award
  • 1994-1999
    Rita Allen Scholar
  • 1995-1998
    Searle Scholar
  • 1998
    Distinction in Teaching Award, UCSF

Selected Publications

  1. Hanlon SL, Li JJ. Re-replication of a Centromere Induces Chromosomal Instability and Aneuploidy. PLoS Genet. 2015 Apr; 11(4):e1005039.
    View on PubMed
  2. Richardson CD, Li JJ. Regulatory mechanisms that prevent re-initiation of DNA replication can be locally modulated at origins by nearby sequence elements. PLoS Genet. 2014 Jun; 10(6):e1004358.
    View on PubMed
  3. Finn KJ, Li JJ. Single-stranded annealing induced by re-initiation of replication origins provides a novel and efficient mechanism for generating copy number expansion via non-allelic homologous recombination. PLoS Genet. 2013; 9(1):e1003192.
    View on PubMed
  4. Green BM, Finn KJ, Li JJ. Loss of DNA replication control is a potent inducer of gene amplification. Science. 2010 Aug 20; 329(5994):943-6.
    View on PubMed
  5. Moses AM, Liku ME, Li JJ, Durbin R. Regulatory evolution in proteins by turnover and lineage-specific changes of cyclin-dependent kinase consensus sites. Proc Natl Acad Sci U S A. 2007 Nov 6; 104(45):17713-8.
    View on PubMed
  6. Green BM, Morreale RJ, Ozaydin B, Derisi JL, Li JJ. Genome-wide mapping of DNA synthesis in Saccharomyces cerevisiae reveals that mechanisms preventing reinitiation of DNA replication are not redundant. Mol Biol Cell. 2006 May; 17(5):2401-14.
    View on PubMed
  7. Liku ME, Nguyen VQ, Rosales AW, Irie K, Li JJ. CDK phosphorylation of a novel NLS-NES module distributed between two subunits of the Mcm2-7 complex prevents chromosomal rereplication. Mol Biol Cell. 2005 Oct; 16(10):5026-39.
    View on PubMed
  8. Green BM, Li JJ. Loss of rereplication control in Saccharomyces cerevisiae results in extensive DNA damage. Mol Biol Cell. 2005 Jan; 16(1):421-32.
    View on PubMed

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