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Joachim J. Li, MD, PhD

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
li_joachim

Associate Professor, Department of Microbiology and Immunology, UCSF

jli@itsa.ucsf.edu

Phone: (415) 476-8782, 476-3841, 514-4081 (voice)
Box 2200, UCSF
San Francisco, CA 94143-2200

View on UCSF Profiles


Additional Websites


Education

University of Chicago, Chicago, IL, B.S., M.S., 1980, Chemistry
Johns Hopkins University School of Medicine, Baltimore, MD, M.D., Ph.D., 1988, Medicine/Molecular Biology


Professional Experience

  • 1980-1982, 1987-1988
    Medical Student, Johns Hopkins University School of Medicine, Baltimore, MD
  • 1982-1987
    Graduate Student (Thomas J. Kelly), Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD
  • 1988
    Postdoctoral Fellow,Yeast Genetics (Phil Hieter), Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD
  • 1989-1993
    Postdoctoral Fellow, Yeast Genetics/Molecular Biology (Ira Herskowitz), Department of Biochemistry and Biophysics, University of California-San Francisco, San Francisco, CA
  • 1993-2000
    Assistant Professor, Department of Microbiology and Immunology, University of California-San Francisco, San Francisco, CA
  • 2000-present
    Associate Professor, Department of Microbiology and Immunology, University of California-San Francisco, San Francisco, CA

Honors & Awards

  • 1977
    United States Presidential Scholar
  • 1979
    Phi Beta Kappa
  • 1979-1980
    National Science Foundation Graduate Fellow
  • 1987
    Michael A. Shanoff Research Award for Ph.D. Thesis, Johns Hopkins University School of Medicine
  • 1989-1990
    Squibb Fellow, Life Sciences Research Foundation
  • 1990-1997
    Markey Scholar Award
  • 1994-1999
    Rita Allen Scholar
  • 1995-1998
    Searle Scholar
  • 1998
    Distinction in Teaching Award, UCSF

Selected Publications

  1. Richardson CD, Li JJ. Regulatory Mechanisms That Prevent Re-initiation of DNA Replication Can Be Locally Modulated at Origins by Nearby Sequence Elements. PLoS Genet. 2014 Jun; 10(6):e1004358.
    View on PubMed
  2. Finn KJ, Li JJ. Single-stranded annealing induced by re-initiation of replication origins provides a novel and efficient mechanism for generating copy number expansion via non-allelic homologous recombination. PLoS Genet. 2013; 9(1):e1003192.
    View on PubMed
  3. Green BM, Finn KJ, Li JJ. Loss of DNA replication control is a potent inducer of gene amplification. Science. 2010 Aug 20; 329(5994):943-6.
    View on PubMed
  4. Moses AM, Liku ME, Li JJ, Durbin R. Regulatory evolution in proteins by turnover and lineage-specific changes of cyclin-dependent kinase consensus sites. Proc Natl Acad Sci U S A. 2007 Nov 6; 104(45):17713-8.
    View on PubMed
  5. Green BM, Morreale RJ, Ozaydin B, Derisi JL, Li JJ. Genome-wide mapping of DNA synthesis in Saccharomyces cerevisiae reveals that mechanisms preventing reinitiation of DNA replication are not redundant. Mol Biol Cell. 2006 May; 17(5):2401-14.
    View on PubMed
  6. Liku ME, Nguyen VQ, Rosales AW, Irie K, Li JJ. CDK phosphorylation of a novel NLS-NES module distributed between two subunits of the Mcm2-7 complex prevents chromosomal rereplication. Mol Biol Cell. 2005 Oct; 16(10):5026-39.
    View on PubMed
  7. Green BM, Li JJ. Loss of rereplication control in Saccharomyces cerevisiae results in extensive DNA damage. Mol Biol Cell. 2005 Jan; 16(1):421-32.
    View on PubMed

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