Long-Cheng Li, MD

Long-Cheng Li, MD

Associate Professor In Residence, Department of Urology, UCSF


Phone: (415) 476-3802 (voice)
Box 3110, UCSF
San Francisco, CA 94143-3110

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Cancer Center Membership

Program Member » Prostate Cancer

Additional Websites


Tongji Medical University, China, MD, 1979-1984, Medicine
Tongji Medical University, China, MChir, 1988-1991, Surgery
Palermo University, Italy, Postdoc, 1997-1998, Urology
University of California, San Francisco, Postdoc, 1999-2001, Molecular Biology

Professional Experience

  • 1983 - 1984
    Intern, Medicine, Tongji Medical University (China)
  • 1984-1988
    Resident, Surgery and Urology, Shashi Second Hospital, Hubei (China)
  • 1989-1991
    Chief Resident, Urology, Tongji Medical University (China)
  • 1991-1996
    Attending Urologist, Tongji Medical University (China)
  • 2000 - 2001
    Bioinformatics Scientist, DoubleTwist, Inc., Oakland, CA
  • 2001 - 2006
    Research Scientist, Urology, Northern California Institute for Research and Education (NCIRE), SF VAMC
  • 2006-2007
    Assistant Researcher, Dept. of Urology, University of California San Francisco, San Francisco, CA
  • 2007-2010
    Assistant Adjunct Professor, Dept. of Urology, University of California San Francisco, San Francisco, CA
  • 2010-2011
    Assistant Professor, Dept. of Urology, University of California San Francisco, San Francisco, CA
  • 2010-2011
    Associate Professor in Residence, Dept. of Urology, University of California San Francisco, San Francisco, CA

Honors & Awards

  • 1997
    Société Internationale d'Urologie Fellowship

Selected Publications

  1. Wang J, Place RF, Portnoy V, Huang V, Kang MR, Kosaka M, Ho MK, Li LC. Inducing gene expression by targeting promoter sequences using small activating RNAs. J Biol Methods. 2015 Mar 11; 2(1).
    View on PubMed
  2. Wang C, Chen Z, Ge Q, Hu J, Li F, Hu J, Xu H, Ye Z, Li LC. Up-regulation of p21(WAF1/CIP1) by miRNAs and its implications in bladder cancer cells. FEBS Lett. 2014 Dec 20; 588(24):4654-64.
    View on PubMed
  3. Wang J, Huang V, Ye L, Bárcena A, Lin G, Lue TF, Li LC. Identification of Small Activating RNAs that Enhance Endogenous OCT4 Expression in Human Mesenchymal Stem Cells. Stem Cells Dev. 2015 Feb 1; 24(3):345-53.
    View on PubMed
  4. Guo D, Barry L, Lin SS, Huang V, Li LC. RNAa in action: From the exception to the norm. RNA Biol. 2014 Oct 3; 11(10):1221-5.
    View on PubMed
  5. Li G, Pan T, Guo D, Li LC. Regulatory Variants and Disease: The E-Cadherin -160C/A SNP as an Example. Mol Biol Int. 2014; 2014:967565.
    View on PubMed
  6. Jiao L, Deng Z, Xu C, Yu Y, Li Y, Yang C, Chen J, Liu Z, Huang G, Li LC, Sun Y. miR-663 induces castration-resistant prostate cancer transformation and predicts clinical recurrence. J Cell Physiol. 2014 Jul; 229(7):834-44.
    View on PubMed
  7. Huang V, Li LC. Demystifying the nuclear function of Argonaute proteins. RNA Biol. 2014 Jan; 11(1):18-24.
    View on PubMed
  8. Li LC. Chromatin remodeling by the small RNA machinery in mammalian cells. Epigenetics. 2014 Jan; 9(1):45-52.
    View on PubMed
  9. Huang V, Zheng J, Qi Z, Wang J, Place RF, Yu J, Li H, Li LC. Ago1 Interacts with RNA polymerase II and binds to the promoters of actively transcribed genes in human cancer cells. PLoS Genet. 2013; 9(9):e1003821.
    View on PubMed
  10. Ren S, Kang MR, Wang J, Huang V, Place RF, Sun Y, Li LC. Targeted induction of endogenous NKX3-1 by small activating RNA inhibits prostate tumor growth. Prostate. 2013 Oct; 73(14):1591-601.
    View on PubMed
  11. Wang T, Li M, Yuan H, Zhan Y, Xu H, Wang S, Yang W, Liu J, Ye Z, Li LC. saRNA guided iNOS up-regulation improves erectile function of diabetic rats. J Urol. 2013 Aug; 190(2):790-8.
    View on PubMed
  12. Ahmed M, Li LC. Adaptation and clonal selection models of castration-resistant prostate cancer: current perspective. Int J Urol. 2013 Apr; 20(4):362-71.
    View on PubMed
  13. Kosaka M, Kang MR, Yang G, Li LC. Targeted p21WAF1/CIP1 activation by RNAa inhibits hepatocellular carcinoma cells. Nucleic Acid Ther. 2012 Oct; 22(5):335-43.
    View on PubMed
  14. Kang MR, Yang G, Place RF, Charisse K, Epstein-Barash H, Manoharan M, Li LC. Intravesical delivery of small activating RNA formulated into lipid nanoparticles inhibits orthotopic bladder tumor growth. Cancer Res. 2012 Oct 1; 72(19):5069-79.
    View on PubMed
  15. Kang MR, Yang G, Charisse K, Epstein-Barash H, Manoharan M, Li LC. An orthotopic bladder tumor model and the evaluation of intravesical saRNA treatment. J Vis Exp. 2012; (65).
    View on PubMed
  16. Wang X, Wang J, Huang V, Place RF, Li LC. Induction of NANOG expression by targeting promoter sequence with small activating RNA antagonizes retinoic acid-induced differentiation. Biochem J. 2012 May 1; 443(3):821-8.
    View on PubMed
  17. Place RF, Wang J, Noonan EJ, Meyers R, Manoharan M, Charisse K, Duncan R, Huang V, Wang X, Li LC. Formulation of Small Activating RNA Into Lipidoid Nanoparticles Inhibits Xenograft Prostate Tumor Growth by Inducing p21 Expression. Mol Ther Nucleic Acids. 2012; 1:e15.
    View on PubMed
  18. Huang V, Li LC. miRNA goes nuclear. RNA Biol. 2012 Mar; 9(3):269-73.
    View on PubMed
  19. Wang J, Li LC. Small RNA and its application in andrology and urology. Transl Androl Urol. 2012; 1(1):33-43.
    View on PubMed
  20. Huang V, Place RF, Portnoy V, Wang J, Qi Z, Jia Z, Yu A, Shuman M, Yu J, Li LC. Upregulation of Cyclin B1 by miRNA and its implications in cancer. Nucleic Acids Res. 2012 Feb; 40(4):1695-707.
    View on PubMed

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